Gene name: NOT3
Reference locus (S288C): YIL038C
Gene biotype: protein_coding
Description: General negative regulator of transcription subunit 3; Component of the CCR4-NOT core complex, involved in mRNA decapping; involved in transcription initiation and elongation and in mRNA degradation; conserved lysine in human homolog of Not3p and Not5p is mutated in cancers
Top 10 interactors (score): CCR4 (0.999); CDC39 (0.999); MOT2 (0.999); CAF40 (0.999); POP2 (0.999); CDC36 (0.999); NOT5 (0.999); CAF130 (0.987); CAF16 (0.97); DHH1 (0.933); BTT1 (0.917); PAT1 (0.895); CAF4 (0.888); XRN1 (0.865); NGL1 (0.828); PUF3 (0.804); WHI4 (0.795); PUF2 (0.751); EDC3 (0.72); DCS1 (0.675)
Homologues (species, bitscore): CNOT3 (Homo sapiens, 216.9); Cnot3 (Mus musculus, 216.9); cnot3a (Danio rerio, 196.8); cnot3 (Xenopus tropicalis, 192.2); Not3 (Drosophila melanogaster, 202.2); ntl-3 (Caenorhabditis elegans, 158.3); AT5G18230 (Arabidopsis thaliana, 161.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:276970-279480:- | gene-YIL038C_AKU4011 | rna-NM_001179388.3_AKU4011 | cds-NP_012226.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:138410-140920:- | gene-YIL038C_BG1 | rna-NM_001179388.3_BG1 | cds-NP_012226.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:283240-285750:- | gene-YIL038C_Bruggeman | rna-NM_001179388.3_Bruggeman | cds-NP_012226.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:271144-273654:- | gene-YIL038C_CAT1 | rna-NM_001179388.3_CAT1 | cds-NP_012226.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:276797-279307:- | gene-YIL038C_CBS1585 | rna-NM_001179388.3_CBS1585 | cds-NP_012226.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:272118-274628:- | gene-YIL038C_CBS436 | rna-NM_001179388.3_CBS436 | cds-NP_012226.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:273410-275920:- | gene-YIL038C_CBS6412 | rna-NM_001179388.3_CBS6412 | cds-NP_012226.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:268961-271471:- | gene-YIL038C_CBS6413 | rna-NM_001179388.3_CBS6413 | cds-NP_012226.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:272054-274564:- | gene-YIL038C_CENPK1137D | rna-NM_001179388.3_CENPK1137D | cds-NP_012226.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:260884-263394:- | gene-YIL038C_EthanolRed | rna-NM_001179388.3_EthanolRed | cds-NP_012226.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:278423-280933:- | gene-YIL038C_FaliES1 | rna-NM_001179388.3_FaliES1 | cds-NP_012226.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:17934-20444:+ | gene-YIL038C_JAY291 | rna-NM_001179388.3_JAY291 | cds-NP_012226.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:280090-282600:- | gene-YIL038C_MUCL30387 | rna-NM_001179388.3_MUCL30387 | cds-NP_012226.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:276693-279203:- | gene-YIL038C_MUCL30388 | rna-NM_001179388.3_MUCL30388 | cds-NP_012226.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:277638-280148:- | gene-YIL038C_MUCL39482 | rna-NM_001179388.3_MUCL39482 | cds-NP_012226.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:280783-283293:- | gene-YIL038C_MUCL42920 | rna-NM_001179388.3_MUCL42920 | cds-NP_012226.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:280142-282652:- | gene-YIL038C_NCIM3186 | rna-NM_001179388.3_NCIM3186 | cds-NP_012226.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:281911-284421:- | gene-YIL038C_NCYC1407 | rna-NM_001179388.3_NCYC1407 | cds-NP_012226.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:275173-277683:- | gene-YIL038C_PE2H3 | rna-NM_001179388.3_PE2H3 | cds-NP_012226.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:269879-272389:- | gene-YIL038C_PE2H4 | rna-NM_001179388.3_PE2H4 | cds-NP_012226.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:280142-282652:- | gene-YIL038C_S288C | rna-NM_001179388.3_S288C | cds-NP_012226.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:43505-46015:+ | gene-YIL038C_SA1 | rna-NM_001179388.3_SA1 | cds-NP_012226.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:277092-279602:- | gene-YIL038C_ThermosaccDry | rna-NM_001179388.3_ThermosaccDry | cds-NP_012226.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:274280-276790:- | gene-YIL038C_VR1 | rna-NM_001179388.3_VR1 | cds-NP_012226.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:250946-253456:- | gene-YIL038C_ZTW1 | rna-NM_001179388.3_ZTW1 | cds-NP_012226.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:273021-275537:- | gene-YIL038C_Sparadoxus | rna-NM_001179388.3_Sparadoxus | cds-NP_012226.3_Sparadoxus | 90.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |