Gene name: NOP53
Reference locus (S288C): YPL146C
Gene biotype: protein_coding
Description: Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p and with the nucleolar proteins Nop17p and Nip7p; null mutant is viable but growth is severely impaired; Belongs to the NOP53 family
Top 10 interactors (score): CIC1 (0.999); NOG1 (0.999); SPB1 (0.999); NOP15 (0.999); RPF2 (0.999); NSA2 (0.999); EBP2 (0.998); NOP7 (0.998); MTR4 (0.998); NOG2 (0.998); RLP24 (0.997); NOP58 (0.997); NOP4 (0.997); MAK5 (0.996); NOC2 (0.996); SAS10 (0.996); CGR1 (0.996); MAK16 (0.995); NOP2 (0.995); NIP7 (0.995)
Homologues (species, bitscore): GLTSCR2 (Homo sapiens, 79.0); Gltscr2 (Mus musculus, 73.2); gltscr2 (Danio rerio, 68.6); CG1785 (Drosophila melanogaster, 66.2); Y39B6A.33 (Caenorhabditis elegans, 52.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:253817-255184:- | gene-YPL146C_AKU4011 | rna-NM_001183960.1_AKU4011 | cds-NP_015179.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:459503-460870:- | gene-YPL146C_BG1 | rna-NM_001183960.1_BG1 | cds-NP_015179.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:279810-281180:- | gene-YPL146C_Bruggeman | rna-NM_001183960.1_Bruggeman | cds-NP_015179.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:276492-277859:- | gene-YPL146C_CAT1 | rna-NM_001183960.1_CAT1 | cds-NP_015179.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:257880-259250:- | gene-YPL146C_CBS1585 | rna-NM_001183960.1_CBS1585 | cds-NP_015179.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:272555-273925:- | gene-YPL146C_CBS436 | rna-NM_001183960.1_CBS436 | cds-NP_015179.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:262558-263925:- | gene-YPL146C_CBS6412 | rna-NM_001183960.1_CBS6412 | cds-NP_015179.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:254522-255889:- | gene-YPL146C_CBS6413 | rna-NM_001183960.1_CBS6413 | cds-NP_015179.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:276064-277431:- | gene-YPL146C_CENPK1137D | rna-NM_001183960.1_CENPK1137D | cds-NP_015179.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:252507-253874:- | gene-YPL146C_EthanolRed | rna-NM_001183960.1_EthanolRed | cds-NP_015179.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:260099-261466:- | gene-YPL146C_FaliES1 | rna-NM_001183960.1_FaliES1 | cds-NP_015179.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:104387-105754:+ | gene-YPL146C_JAY291 | rna-NM_001183960.1_JAY291 | cds-NP_015179.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:271053-272423:- | gene-YPL146C_MUCL30387 | rna-NM_001183960.1_MUCL30387 | cds-NP_015179.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:269070-270437:- | gene-YPL146C_MUCL30388 | rna-NM_001183960.1_MUCL30388 | cds-NP_015179.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:251209-252579:- | gene-YPL146C_MUCL39482 | rna-NM_001183960.1_MUCL39482 | cds-NP_015179.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:308450-309820:- | gene-YPL146C_MUCL42920 | rna-NM_001183960.1_MUCL42920 | cds-NP_015179.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:276145-277512:- | gene-YPL146C_NCIM3186 | rna-NM_001183960.1_NCIM3186 | cds-NP_015179.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:257672-259039:- | gene-YPL146C_NCYC1407 | rna-NM_001183960.1_NCYC1407 | cds-NP_015179.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:265119-266486:- | gene-YPL146C_PE2H3 | rna-NM_001183960.1_PE2H3 | cds-NP_015179.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:264748-266115:- | gene-YPL146C_PE2H4 | rna-NM_001183960.1_PE2H4 | cds-NP_015179.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:276162-277529:- | gene-YPL146C_S288C | rna-NM_001183960.1_S288C | cds-NP_015179.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:96158-97525:+ | gene-YPL146C_SA1 | rna-NM_001183960.1_SA1 | cds-NP_015179.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:259897-261264:- | gene-YPL146C_ThermosaccDry | rna-NM_001183960.1_ThermosaccDry | cds-NP_015179.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:274876-276243:- | gene-YPL146C_VR1 | rna-NM_001183960.1_VR1 | cds-NP_015179.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:259225-260595:- | gene-YPL146C_ZTW1 | rna-NM_001183960.1_ZTW1 | cds-NP_015179.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:260888-262243:- | gene-YPL146C_Sparadoxus | rna-NM_001183960.1_Sparadoxus | cds-NP_015179.1_Sparadoxus | 89.3 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |