NOP1 (YDL014W)


Gene profile

Gene name: NOP1
Reference locus (S288C): YDL014W
Gene biotype: protein_coding

Description: rRNA 2'-O-methyltransferase fibrillarin; Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; ortholog of mammalian fibrillarin; inviability of the null mutant is functionally complemented by human FBL

Top 10 interactors (score): UTP13 (0.999); SPB1 (0.999); IMP3 (0.999); PNO1 (0.999); NOP15 (0.999); NOP2 (0.999); UTP5 (0.999); RPS14A (0.999); RRP9 (0.999); DIP2 (0.999); UTP15 (0.999); NOP56 (0.999); NAN1 (0.999); ERB1 (0.999); PWP2 (0.999); NHP2 (0.999); NOP7 (0.999); UTP30 (0.999); NIP7 (0.999); YTM1 (0.999)

Homologues (species, bitscore): FBL (Homo sapiens, 426.4); Fbl (Mus musculus, 433.0); fbl (Danio rerio, 436.4); fbl (Xenopus tropicalis, 438.7); Fib (Drosophila melanogaster, 433.0); fib-1 (Caenorhabditis elegans, 441.0); FIB2 (Arabidopsis thaliana, 426.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:413450-414433:+ gene-YDL014W_AKU4011 rna-NM_001180073.1_AKU4011 cds-NP_010270.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:135452-136435:- gene-YDL014W_BG1 rna-NM_001180073.1_BG1 cds-NP_010270.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:434017-435000:+ gene-YDL014W_Bruggeman rna-NM_001180073.1_Bruggeman cds-NP_010270.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:426913-427896:+ gene-YDL014W_CAT1 rna-NM_001180073.1_CAT1 cds-NP_010270.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:409863-410846:+ gene-YDL014W_CBS1585 rna-NM_001180073.1_CBS1585 cds-NP_010270.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:427389-428372:+ gene-YDL014W_CBS436 rna-NM_001180073.1_CBS436 cds-NP_010270.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:407632-408561:+ gene-YDL014W_CBS6412 rna-NM_001180073.1_CBS6412 cds-NP_010270.1_CBS6412 94.4 94.5 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:429629-430612:+ gene-YDL014W_CBS6413 rna-NM_001180073.1_CBS6413 cds-NP_010270.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:426226-427209:+ gene-YDL014W_CENPK1137D rna-NM_001180073.1_CENPK1137D cds-NP_010270.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:422282-423265:+ gene-YDL014W_EthanolRed rna-NM_001180073.1_EthanolRed cds-NP_010270.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:428474-429457:+ gene-YDL014W_FaliES1 rna-NM_001180073.1_FaliES1 cds-NP_010270.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000370.1:42958-43941:+ gene-YDL014W_JAY291 rna-NM_001180073.1_JAY291 cds-NP_010270.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:427907-428890:+ gene-YDL014W_MUCL30387 rna-NM_001180073.1_MUCL30387 cds-NP_010270.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:418363-419346:+ gene-YDL014W_MUCL30388 rna-NM_001180073.1_MUCL30388 cds-NP_010270.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:411537-412520:+ gene-YDL014W_MUCL39482 rna-NM_001180073.1_MUCL39482 cds-NP_010270.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:333415-334398:+ gene-YDL014W_MUCL42920 rna-NM_001180073.1_MUCL42920 cds-NP_010270.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:427287-428270:+ gene-YDL014W_NCIM3186 rna-NM_001180073.1_NCIM3186 cds-NP_010270.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:410959-411942:+ gene-YDL014W_NCYC1407 rna-NM_001180073.1_NCYC1407 cds-NP_010270.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:418440-419423:+ gene-YDL014W_PE2H3 rna-NM_001180073.1_PE2H3 cds-NP_010270.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:417798-418781:+ gene-YDL014W_PE2H4 rna-NM_001180073.1_PE2H4 cds-NP_010270.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:427364-428347:+ gene-YDL014W_S288C rna-NM_001180073.1_S288C cds-NP_010270.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:6619-7602:- gene-YDL014W_SA1 rna-NM_001180073.1_SA1 cds-NP_010270.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:427934-428917:+ gene-YDL014W_ThermosaccDry rna-NM_001180073.1_ThermosaccDry cds-NP_010270.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:430945-431928:+ gene-YDL014W_VR1 rna-NM_001180073.1_VR1 cds-NP_010270.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:425833-426816:+ gene-YDL014W_ZTW1 rna-NM_001180073.1_ZTW1 cds-NP_010270.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:429980-430972:+ gene-YDL014W_Sparadoxus rna-NM_001180073.1_Sparadoxus cds-NP_010270.1_Sparadoxus 92.1 98.7 Verified 1 1 1 False True False False False

Additional files