Gene name: NOB1
Reference locus (S288C): YOR056C
Gene biotype: protein_coding
Description: 20S-pre-rRNA D-site endonuclease NOB1; Protein involved in proteasomal and 40S ribosomal subunit biogenesis; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA; cleavage is activated by Fun12p, a GTPase and translation initiation factor; relocalizes from nucleus to nucleolus upon DNA replication stress; Belongs to the NOB1 family
Top 10 interactors (score): NOP9 (0.999); LTV1 (0.999); TSR1 (0.999); ENP1 (0.999); RIO1 (0.999); PNO1 (0.999); RIO2 (0.999); NMD3 (0.994); RRP8 (0.994); NOC4 (0.992); NOP4 (0.992); RCL1 (0.991); IMP4 (0.991); BRX1 (0.991); FAP7 (0.991); BUD23 (0.99); PWP2 (0.99); NOP2 (0.99); BMS1 (0.99); RRP5 (0.989)
Homologues (species, bitscore): NOB1 (Homo sapiens, 114.8); Nob1 (Mus musculus, 115.2); nob1 (Danio rerio, 125.2); nob1 (Xenopus tropicalis, 120.9); CG2972 (Drosophila melanogaster, 106.3); Y54E10BR.4 (Caenorhabditis elegans, 124.8); AT5G41190 (Arabidopsis thaliana, 97.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:414583-415962:- | gene-YOR056C_AKU4011 | rna-NM_001183475.1_AKU4011 | cds-NP_014699.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000023.1:1256-2635:+ | gene-YOR056C_BG1 | rna-NM_001183475.1_BG1 | cds-NP_014699.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:417296-418675:- | gene-YOR056C_Bruggeman | rna-NM_001183475.1_Bruggeman | cds-NP_014699.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:415480-416859:- | gene-YOR056C_CAT1 | rna-NM_001183475.1_CAT1 | cds-NP_014699.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:409269-410648:- | gene-YOR056C_CBS1585 | rna-NM_001183475.1_CBS1585 | cds-NP_014699.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:413574-414953:- | gene-YOR056C_CBS436 | rna-NM_001183475.1_CBS436 | cds-NP_014699.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:408596-409975:- | gene-YOR056C_CBS6412 | rna-NM_001183475.1_CBS6412 | cds-NP_014699.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:415930-417259:- | gene-YOR056C_CBS6413 | rna-NM_001183475.1_CBS6413 | cds-NP_014699.1_CBS6413 | 96.0 | 96.3 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:430231-431610:- | gene-YOR056C_CENPK1137D | rna-NM_001183475.1_CENPK1137D | cds-NP_014699.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:411300-412679:- | gene-YOR056C_EthanolRed | rna-NM_001183475.1_EthanolRed | cds-NP_014699.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:414636-416015:- | gene-YOR056C_FaliES1 | rna-NM_001183475.1_FaliES1 | cds-NP_014699.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000195.1:6713-8092:+ | gene-YOR056C_JAY291 | rna-NM_001183475.1_JAY291 | cds-NP_014699.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:422076-423455:- | gene-YOR056C_MUCL30387 | rna-NM_001183475.1_MUCL30387 | cds-NP_014699.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:426486-427865:- | gene-YOR056C_MUCL30388 | rna-NM_001183475.1_MUCL30388 | cds-NP_014699.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:416754-418133:- | gene-YOR056C_MUCL39482 | rna-NM_001183475.1_MUCL39482 | cds-NP_014699.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:431563-432942:- | gene-YOR056C_MUCL42920 | rna-NM_001183475.1_MUCL42920 | cds-NP_014699.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:430136-431515:- | gene-YOR056C_NCIM3186 | rna-NM_001183475.1_NCIM3186 | cds-NP_014699.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:423423-424802:- | gene-YOR056C_NCYC1407 | rna-NM_001183475.1_NCYC1407 | cds-NP_014699.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:422278-423657:- | gene-YOR056C_PE2H3 | rna-NM_001183475.1_PE2H3 | cds-NP_014699.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:432659-434038:- | gene-YOR056C_PE2H4 | rna-NM_001183475.1_PE2H4 | cds-NP_014699.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:430247-431626:- | gene-YOR056C_S288C | rna-NM_001183475.1_S288C | cds-NP_014699.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:398173-399552:- | gene-YOR056C_SA1 | rna-NM_001183475.1_SA1 | cds-NP_014699.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:413177-414556:- | gene-YOR056C_ThermosaccDry | rna-NM_001183475.1_ThermosaccDry | cds-NP_014699.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:414593-415972:- | gene-YOR056C_VR1 | rna-NM_001183475.1_VR1 | cds-NP_014699.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:147789-149168:- | gene-YOR056C_ZTW1 | rna-NM_001183475.1_ZTW1 | cds-NP_014699.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:420661-422058:- | gene-YOR056C_Sparadoxus | rna-NM_001183475.1_Sparadoxus | cds-NP_014699.1_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |