NNR1 (YNL200C)


Gene profile

Gene name: NNR1
Reference locus (S288C): YNL200C
Gene biotype: protein_coding

Description: NADHX epimerase; catalyzes isomerization of (R)- and (S)-NADHX; homologous to AIBP in mammals and the N- terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the NnrE/AIBP family

Top 10 interactors (score): NNR2 (0.987); DCP2 (0.982); DCP1 (0.979); TFS1 (0.975); GAD1 (0.954); DCS2 (0.932); SOL4 (0.928); MSC1 (0.92); PGM2 (0.918); GLK1 (0.891); OM45 (0.887); GLC3 (0.885); DHH1 (0.882); STF2 (0.872); YJR096W (0.868); YKL091C (0.854); PNC1 (0.849); GSY2 (0.846); UIP4 (0.842); GOR1 (0.841)

Homologues (species, bitscore): APOA1BP (Homo sapiens, 171.0); Apoa1bp (Mus musculus, 177.2); apoa1bp (Danio rerio, 174.5); apoa1bp (Xenopus tropicalis, 170.2); CG2974 (Drosophila melanogaster, 179.1); Y18D10A.3 (Caenorhabditis elegans, 166.0); PDXH (Arabidopsis thaliana, 174.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:257489-258229:- gene-YNL200C_AKU4011 rna-NM_001183038.1_AKU4011 cds-NP_014199.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:161438-162178:- gene-YNL200C_BG1 rna-NM_001183038.1_BG1 cds-NP_014199.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:267537-268277:- gene-YNL200C_Bruggeman rna-NM_001183038.1_Bruggeman cds-NP_014199.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:309779-310519:- gene-YNL200C_CAT1 rna-NM_001183038.1_CAT1 cds-NP_014199.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:258134-258874:- gene-YNL200C_CBS1585 rna-NM_001183038.1_CBS1585 cds-NP_014199.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:326422-327162:- gene-YNL200C_CBS436 rna-NM_001183038.1_CBS436 cds-NP_014199.1_CBS436 99.4 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:253547-254287:- gene-YNL200C_CBS6412 rna-NM_001183038.1_CBS6412 cds-NP_014199.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:254568-255308:- gene-YNL200C_CBS6413 rna-NM_001183038.1_CBS6413 cds-NP_014199.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:257561-258301:- gene-YNL200C_CENPK1137D rna-NM_001183038.1_CENPK1137D cds-NP_014199.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:254457-255197:- gene-YNL200C_EthanolRed rna-NM_001183038.1_EthanolRed cds-NP_014199.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:250370-251110:- gene-YNL200C_FaliES1 rna-NM_001183038.1_FaliES1 cds-NP_014199.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000260.1:67257-67997:+ gene-YNL200C_JAY291 rna-NM_001183038.1_JAY291 cds-NP_014199.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:263324-264064:- gene-YNL200C_MUCL30387 rna-NM_001183038.1_MUCL30387 cds-NP_014199.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:297690-298430:- gene-YNL200C_MUCL30388 rna-NM_001183038.1_MUCL30388 cds-NP_014199.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:255373-256113:- gene-YNL200C_MUCL39482 rna-NM_001183038.1_MUCL39482 cds-NP_014199.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:257740-258480:- gene-YNL200C_MUCL42920 rna-NM_001183038.1_MUCL42920 cds-NP_014199.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:263682-264422:- gene-YNL200C_NCIM3186 rna-NM_001183038.1_NCIM3186 cds-NP_014199.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:257463-258203:- gene-YNL200C_NCYC1407 rna-NM_001183038.1_NCYC1407 cds-NP_014199.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:254375-255115:- gene-YNL200C_PE2H3 rna-NM_001183038.1_PE2H3 cds-NP_014199.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:253763-254503:- gene-YNL200C_PE2H4 rna-NM_001183038.1_PE2H4 cds-NP_014199.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:263713-264453:- gene-YNL200C_S288C rna-NM_001183038.1_S288C cds-NP_014199.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:149146-149886:+ gene-YNL200C_SA1 rna-NM_001183038.1_SA1 cds-NP_014199.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:251227-251967:- gene-YNL200C_ThermosaccDry rna-NM_001183038.1_ThermosaccDry cds-NP_014199.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:269729-270469:- gene-YNL200C_VR1 rna-NM_001183038.1_VR1 cds-NP_014199.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:161057-161797:- gene-YNL200C_ZTW1 rna-NM_001183038.1_ZTW1 cds-NP_014199.1_ZTW1 99.1 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:261578-262318:- gene-YNL200C_Sparadoxus rna-NM_001183038.1_Sparadoxus cds-NP_014199.1_Sparadoxus 92.7 100.0 Verified 1 1 1 False True False False False

Additional files