Gene name: NNK1
Reference locus (S288C): YKL171W
Gene biotype: protein_coding
Description: Nitrogen network kinase 1; Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm
Top 10 interactors (score): SDH8 (0.746); YDL199C (0.727); YDR220C (0.716); YCR087C-A (0.697); YOR331C (0.691); SNF3 (0.679); YLR149C (0.666); PDP3 (0.66); TOS3 (0.656); SEC4 (0.653); SAK1 (0.644); URE2 (0.644); FMP48 (0.633); YPL150W (0.621); ELM1 (0.619); OSW5 (0.612); SKY1 (0.599); SCY1 (0.565); TSR3 (0.562); VHS1 (0.543)
Homologues (species, bitscore): DCLK1 (Homo sapiens, 77.8); Dclk1 (Mus musculus, 78.2); dckl1b (Danio rerio, 80.9); dclk1 (Xenopus tropicalis, 80.9); Sik3 (Drosophila melanogaster, 78.6); mnk-1 (Caenorhabditis elegans, 84.0); MPK19 (Arabidopsis thaliana, 68.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:114336-117122:+ | gene-YKL171W_AKU4011 | rna-NM_001179737.1_AKU4011 | cds-NP_012750.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:90885-93671:+ | gene-YKL171W_BG1 | rna-NM_001179737.1_BG1 | cds-NP_012750.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:131738-134524:+ | gene-YKL171W_Bruggeman | rna-NM_001179737.1_Bruggeman | cds-NP_012750.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:126680-129466:+ | gene-YKL171W_CAT1 | rna-NM_001179737.1_CAT1 | cds-NP_012750.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:126320-129106:+ | gene-YKL171W_CBS1585 | rna-NM_001179737.1_CBS1585 | cds-NP_012750.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:125076-127862:+ | gene-YKL171W_CBS436 | rna-NM_001179737.1_CBS436 | cds-NP_012750.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:111910-114696:+ | gene-YKL171W_CBS6412 | rna-NM_001179737.1_CBS6412 | cds-NP_012750.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:127036-129822:+ | gene-YKL171W_CBS6413 | rna-NM_001179737.1_CBS6413 | cds-NP_012750.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:127301-130087:+ | gene-YKL171W_CENPK1137D | rna-NM_001179737.1_CENPK1137D | cds-NP_012750.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:125240-128026:+ | gene-YKL171W_EthanolRed | rna-NM_001179737.1_EthanolRed | cds-NP_012750.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:125941-128727:+ | gene-YKL171W_FaliES1 | rna-NM_001179737.1_FaliES1 | cds-NP_012750.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:124899-127685:+ | gene-YKL171W_JAY291 | rna-NM_001179737.1_JAY291 | cds-NP_012750.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:134026-136812:+ | gene-YKL171W_MUCL30387 | rna-NM_001179737.1_MUCL30387 | cds-NP_012750.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:128382-131168:+ | gene-YKL171W_MUCL30388 | rna-NM_001179737.1_MUCL30388 | cds-NP_012750.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:126375-129161:+ | gene-YKL171W_MUCL39482 | rna-NM_001179737.1_MUCL39482 | cds-NP_012750.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:130701-133487:+ | gene-YKL171W_MUCL42920 | rna-NM_001179737.1_MUCL42920 | cds-NP_012750.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:127464-130250:+ | gene-YKL171W_NCIM3186 | rna-NM_001179737.1_NCIM3186 | cds-NP_012750.1_NCIM3186 | 94.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:126399-129185:+ | gene-YKL171W_NCYC1407 | rna-NM_001179737.1_NCYC1407 | cds-NP_012750.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:133451-136237:+ | gene-YKL171W_PE2H3 | rna-NM_001179737.1_PE2H3 | cds-NP_012750.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:129745-132531:+ | gene-YKL171W_PE2H4 | rna-NM_001179737.1_PE2H4 | cds-NP_012750.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:127475-130261:+ | gene-YKL171W_S288C | rna-NM_001179737.1_S288C | cds-NP_012750.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:43675-46461:+ | gene-YKL171W_SA1 | rna-NM_001179737.1_SA1 | cds-NP_012750.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:126641-129427:+ | gene-YKL171W_ThermosaccDry | rna-NM_001179737.1_ThermosaccDry | cds-NP_012750.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:125156-127942:+ | gene-YKL171W_VR1 | rna-NM_001179737.1_VR1 | cds-NP_012750.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:125031-127817:+ | gene-YKL171W_ZTW1 | rna-NM_001179737.1_ZTW1 | cds-NP_012750.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:139546-142332:+ | gene-YKL171W_Sparadoxus | rna-NM_001179737.1_Sparadoxus | cds-NP_012750.1_Sparadoxus | 87.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |