Gene name: NMA111
Reference locus (S288C): YNL123W
Gene biotype: protein_coding
Description: Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases; Belongs to the peptidase S1C family
Top 10 interactors (score): MCA1 (0.969); NUC1 (0.962); BXI1 (0.96); BIR1 (0.912); AIF1 (0.898); FAA1 (0.883); KEX1 (0.862); NDI1 (0.829); YBL055C (0.777); FYV10 (0.761); YNL108C (0.754); ATP2 (0.685); FIS1 (0.684); SNO1 (0.657); CDC53 (0.645); CDC48 (0.636); CNE1 (0.632); NAF1 (0.593); YNL115C (0.585); GAL10 (0.573)
Homologues (species, bitscore): HTRA1 (Homo sapiens, 70.1); Htra1 (Mus musculus, 72.4); htra1a (Danio rerio, 78.2); htra4 (Xenopus tropicalis, 83.2); HtrA2 (Drosophila melanogaster, 68.6); DEG7 (Arabidopsis thaliana, 512.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:388369-391362:+ | gene-YNL123W_AKU4011 | rna-NM_001182961.1_AKU4011 | cds-NP_014276.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:292364-295357:+ | gene-YNL123W_BG1 | rna-NM_001182961.1_BG1 | cds-NP_014276.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:398834-401827:+ | gene-YNL123W_Bruggeman | rna-NM_001182961.1_Bruggeman | cds-NP_014276.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:442147-445140:+ | gene-YNL123W_CAT1 | rna-NM_001182961.1_CAT1 | cds-NP_014276.1_CAT1 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:388989-391982:+ | gene-YNL123W_CBS1585 | rna-NM_001182961.1_CBS1585 | cds-NP_014276.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:457380-460373:+ | gene-YNL123W_CBS436 | rna-NM_001182961.1_CBS436 | cds-NP_014276.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:384442-387435:+ | gene-YNL123W_CBS6412 | rna-NM_001182961.1_CBS6412 | cds-NP_014276.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:385407-388400:+ | gene-YNL123W_CBS6413 | rna-NM_001182961.1_CBS6413 | cds-NP_014276.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:388535-391528:+ | gene-YNL123W_CENPK1137D | rna-NM_001182961.1_CENPK1137D | cds-NP_014276.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:385359-388352:+ | gene-YNL123W_EthanolRed | rna-NM_001182961.1_EthanolRed | cds-NP_014276.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:381261-384254:+ | gene-YNL123W_FaliES1 | rna-NM_001182961.1_FaliES1 | cds-NP_014276.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:37640-40633:+ | gene-YNL123W_JAY291 | rna-NM_001182961.1_JAY291 | cds-NP_014276.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:394488-397481:+ | gene-YNL123W_MUCL30387 | rna-NM_001182961.1_MUCL30387 | cds-NP_014276.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:429942-432935:+ | gene-YNL123W_MUCL30388 | rna-NM_001182961.1_MUCL30388 | cds-NP_014276.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:386268-389261:+ | gene-YNL123W_MUCL39482 | rna-NM_001182961.1_MUCL39482 | cds-NP_014276.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:389258-392251:+ | gene-YNL123W_MUCL42920 | rna-NM_001182961.1_MUCL42920 | cds-NP_014276.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:394654-397647:+ | gene-YNL123W_NCIM3186 | rna-NM_001182961.1_NCIM3186 | cds-NP_014276.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:388400-391393:+ | gene-YNL123W_NCYC1407 | rna-NM_001182961.1_NCYC1407 | cds-NP_014276.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:387389-390382:+ | gene-YNL123W_PE2H3 | rna-NM_001182961.1_PE2H3 | cds-NP_014276.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:386777-389770:+ | gene-YNL123W_PE2H4 | rna-NM_001182961.1_PE2H4 | cds-NP_014276.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:394685-397678:+ | gene-YNL123W_S288C | rna-NM_001182961.1_S288C | cds-NP_014276.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:15834-18827:- | gene-YNL123W_SA1 | rna-NM_001182961.1_SA1 | cds-NP_014276.1_SA1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:382115-385108:+ | gene-YNL123W_ThermosaccDry | rna-NM_001182961.1_ThermosaccDry | cds-NP_014276.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:400775-403768:+ | gene-YNL123W_VR1 | rna-NM_001182961.1_VR1 | cds-NP_014276.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:291947-294940:+ | gene-YNL123W_ZTW1 | rna-NM_001182961.1_ZTW1 | cds-NP_014276.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:392925-395918:+ | gene-YNL123W_Sparadoxus | rna-NM_001182961.1_Sparadoxus | cds-NP_014276.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |