Gene name: NHP6B
Reference locus (S288C): YBR089C-A
Gene biotype: protein_coding
Description: Non-histone chromosomal protein 6B; High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication
Top 10 interactors (score): POB3 (0.96); SPT16 (0.923); ARP9 (0.908); ARP7 (0.891); RSC8 (0.874); HMO1 (0.855); BRF1 (0.851); STH1 (0.848); SFH1 (0.847); ISW1 (0.804); SNF2 (0.797); AFT2 (0.78); NHP6A (0.776); IOC3 (0.769); RSC58 (0.763); ITC1 (0.761); ABF2 (0.753); RPO31 (0.75); HMG1 (0.747); ISW2 (0.747)
Homologues (species, bitscore): TOX (Homo sapiens, 77.0); Tox (Mus musculus, 77.0); tox (Danio rerio, 78.2); tox4 (Xenopus tropicalis, 82.0); Dsp1 (Drosophila melanogaster, 73.9); hmg-1.2 (Caenorhabditis elegans, 75.9); HMG (Arabidopsis thaliana, 99.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:408558-408857:- | gene-YBR089C-A_AKU4011 | rna-NM_001180058.2_AKU4011 | cds-NP_009647.2_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:399595-399894:- | gene-YBR089C-A_BG1 | rna-NM_001180058.2_BG1 | cds-NP_009647.2_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:410133-410432:- | gene-YBR089C-A_Bruggeman | rna-NM_001180058.2_Bruggeman | cds-NP_009647.2_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:413106-413405:- | gene-YBR089C-A_CAT1 | rna-NM_001180058.2_CAT1 | cds-NP_009647.2_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:400843-401142:- | gene-YBR089C-A_CBS1585 | rna-NM_001180058.2_CBS1585 | cds-NP_009647.2_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:408964-409263:- | gene-YBR089C-A_CBS436 | rna-NM_001180058.2_CBS436 | cds-NP_009647.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:499072-499371:- | gene-YBR089C-A_CBS6412 | rna-NM_001180058.2_CBS6412 | cds-NP_009647.2_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:405983-406282:- | gene-YBR089C-A_CBS6413 | rna-NM_001180058.2_CBS6413 | cds-NP_009647.2_CBS6413 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:419942-420241:- | gene-YBR089C-A_CENPK1137D | rna-NM_001180058.2_CENPK1137D | cds-NP_009647.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:535350-535649:- | gene-YBR089C-A_EthanolRed | rna-NM_001180058.2_EthanolRed | cds-NP_009647.2_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:424633-424932:- | gene-YBR089C-A_FaliES1 | rna-NM_001180058.2_FaliES1 | cds-NP_009647.2_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000013.1:2249-2548:+ | gene-YBR089C-A_JAY291 | rna-NM_001180058.2_JAY291 | cds-NP_009647.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:412370-412669:- | gene-YBR089C-A_MUCL30387 | rna-NM_001180058.2_MUCL30387 | cds-NP_009647.2_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:411365-411664:- | gene-YBR089C-A_MUCL30388 | rna-NM_001180058.2_MUCL30388 | cds-NP_009647.2_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:400834-401133:- | gene-YBR089C-A_MUCL39482 | rna-NM_001180058.2_MUCL39482 | cds-NP_009647.2_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:408047-408346:- | gene-YBR089C-A_MUCL42920 | rna-NM_001180058.2_MUCL42920 | cds-NP_009647.2_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:425987-426286:- | gene-YBR089C-A_NCIM3186 | rna-NM_001180058.2_NCIM3186 | cds-NP_009647.2_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:401766-402065:- | gene-YBR089C-A_NCYC1407 | rna-NM_001180058.2_NCYC1407 | cds-NP_009647.2_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:414382-414681:- | gene-YBR089C-A_PE2H3 | rna-NM_001180058.2_PE2H3 | cds-NP_009647.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:412058-412357:- | gene-YBR089C-A_PE2H4 | rna-NM_001180058.2_PE2H4 | cds-NP_009647.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:426190-426489:- | gene-YBR089C-A_S288C | rna-NM_001180058.2_S288C | cds-NP_009647.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:51216-51515:+ | gene-YBR089C-A_SA1 | rna-NM_001180058.2_SA1 | cds-NP_009647.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:423640-423939:- | gene-YBR089C-A_ThermosaccDry | rna-NM_001180058.2_ThermosaccDry | cds-NP_009647.2_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:405644-405943:- | gene-YBR089C-A_VR1 | rna-NM_001180058.2_VR1 | cds-NP_009647.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:399305-399604:- | gene-YBR089C-A_ZTW1 | rna-NM_001180058.2_ZTW1 | cds-NP_009647.2_ZTW1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:436185-436484:- | gene-YBR089C-A_Sparadoxus | rna-NM_001180058.2_Sparadoxus | cds-NP_009647.2_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |