NGR1 (YBR212W)


Gene profile

Gene name: NGR1
Reference locus (S288C): YBR212W
Gene biotype: protein_coding

Description: RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase

Top 10 interactors (score): RPG1 (0.823); CDC33 (0.79); TIF4632 (0.774); DHH1 (0.761); PBP1 (0.755); RIE1 (0.749); EDC3 (0.731); PRP39 (0.702); WHI3 (0.7); TIF4631 (0.689); NRP1 (0.679); KNS1 (0.671); SCD6 (0.654); HEK2 (0.652); MPT5 (0.647); XRN1 (0.631); MRN1 (0.619); EST2 (0.616); TIF2 (0.602); SES1 (0.601)

Homologues (species, bitscore): TIAL1 (Homo sapiens, 107.1); Tial1 (Mus musculus, 105.1); tial1 (Danio rerio, 112.5); tial1 (Xenopus tropicalis, 102.8); CG15440 (Drosophila melanogaster, 90.5); tiar-1 (Caenorhabditis elegans, 95.5); RBP47A (Arabidopsis thaliana, 172.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:632173-634188:+ gene-YBR212W_AKU4011 rna-NM_001178560.3_AKU4011 cds-NP_009771.3_AKU4011 99.5 99.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:3110-5131:+ gene-YBR212W_BG1 rna-NM_001178560.3_BG1 cds-NP_009771.3_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:633356-635368:+ gene-YBR212W_Bruggeman rna-NM_001178560.3_Bruggeman cds-NP_009771.3_Bruggeman 99.3 99.7 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:636560-638572:+ gene-YBR212W_CAT1 rna-NM_001178560.3_CAT1 cds-NP_009771.3_CAT1 99.3 99.7 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:623705-625720:+ gene-YBR212W_CBS1585 rna-NM_001178560.3_CBS1585 cds-NP_009771.3_CBS1585 99.5 99.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:630159-632171:+ gene-YBR212W_CBS436 rna-NM_001178560.3_CBS436 cds-NP_009771.3_CBS436 99.4 99.7 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:718682-720697:+ gene-YBR212W_CBS6412 rna-NM_001178560.3_CBS6412 cds-NP_009771.3_CBS6412 99.5 99.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:629744-631759:+ gene-YBR212W_CBS6413 rna-NM_001178560.3_CBS6413 cds-NP_009771.3_CBS6413 99.5 99.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:641642-643654:+ gene-YBR212W_CENPK1137D rna-NM_001178560.3_CENPK1137D cds-NP_009771.3_CENPK1137D 99.2 99.7 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:755429-757444:+ gene-YBR212W_EthanolRed rna-NM_001178560.3_EthanolRed cds-NP_009771.3_EthanolRed 99.5 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:648536-650551:+ gene-YBR212W_FaliES1 rna-NM_001178560.3_FaliES1 cds-NP_009771.3_FaliES1 99.5 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000326.1:2914-4935:+ gene-YBR212W_JAY291 rna-NM_001178560.3_JAY291 cds-NP_009771.3_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:635369-637381:+ gene-YBR212W_MUCL30387 rna-NM_001178560.3_MUCL30387 cds-NP_009771.3_MUCL30387 99.3 99.7 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:652447-654459:+ gene-YBR212W_MUCL30388 rna-NM_001178560.3_MUCL30388 cds-NP_009771.3_MUCL30388 99.3 99.7 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:622057-624072:+ gene-YBR212W_MUCL39482 rna-NM_001178560.3_MUCL39482 cds-NP_009771.3_MUCL39482 99.5 99.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:631562-633577:+ gene-YBR212W_MUCL42920 rna-NM_001178560.3_MUCL42920 cds-NP_009771.3_MUCL42920 99.4 99.8 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:647683-649701:+ gene-YBR212W_NCIM3186 rna-NM_001178560.3_NCIM3186 cds-NP_009771.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:623919-625934:+ gene-YBR212W_NCYC1407 rna-NM_001178560.3_NCYC1407 cds-NP_009771.3_NCYC1407 99.5 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:647052-649073:+ gene-YBR212W_PE2H3 rna-NM_001178560.3_PE2H3 cds-NP_009771.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:644728-646749:+ gene-YBR212W_PE2H4 rna-NM_001178560.3_PE2H4 cds-NP_009771.3_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:647886-649904:+ gene-YBR212W_S288C rna-NM_001178560.3_S288C cds-NP_009771.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:3007-5028:+ gene-YBR212W_SA1 rna-NM_001178560.3_SA1 cds-NP_009771.3_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:647546-649561:+ gene-YBR212W_ThermosaccDry rna-NM_001178560.3_ThermosaccDry cds-NP_009771.3_ThermosaccDry 99.5 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:627732-629744:+ gene-YBR212W_VR1 rna-NM_001178560.3_VR1 cds-NP_009771.3_VR1 99.4 99.7 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:620412-622427:+ gene-YBR212W_ZTW1 rna-NM_001178560.3_ZTW1 cds-NP_009771.3_ZTW1 99.4 99.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:664353-666392:+ gene-YBR212W_Sparadoxus rna-NM_001178560.3_Sparadoxus cds-NP_009771.3_Sparadoxus 87.3 99.4 Verified 1 1 1 False True False False False

Additional files