Gene name: NGL3
Reference locus (S288C): YML118W
Gene biotype: protein_coding
Description: 3'-5' exonuclease specific for poly-A RNAs; has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p; NGL3 has a paralog, NGL2, that arose from the whole genome duplication
Top 10 interactors (score): NGL1 (0.934); CCR4 (0.829); RNH70 (0.821); POP2 (0.783); REX2 (0.753); PPT1 (0.697); CDC39 (0.633); GCN3 (0.58); RRP45 (0.567); CDC36 (0.558); RRP40 (0.54); ADY2 (0.499); PAN3 (0.488); CAF40 (0.47); CDC73 (0.459); MOT2 (0.405)
Homologues (species, bitscore): PDE12 (Homo sapiens, 88.2); Pde12 (Mus musculus, 82.0); LOC569547 (Danio rerio, 79.0); pde12 (Xenopus tropicalis, 66.2); angel (Drosophila melanogaster, 70.5); ccr-4 (Caenorhabditis elegans, 60.5); AT1G31500 (Arabidopsis thaliana, 72.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:26034-27550:+ | gene-YML118W_AKU4011 | rna-NM_001182481.1_AKU4011 | cds-NP_013588.1_AKU4011 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:448619-450139:- | gene-YML118W_BG1 | rna-NM_001182481.1_BG1 | cds-NP_013588.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:32246-33765:+ | gene-YML118W_Bruggeman | rna-NM_001182481.1_Bruggeman | cds-NP_013588.1_Bruggeman | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:33852-35371:+ | gene-YML118W_CAT1 | rna-NM_001182481.1_CAT1 | cds-NP_013588.1_CAT1 | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:26033-27549:+ | gene-YML118W_CBS1585 | rna-NM_001182481.1_CBS1585 | cds-NP_013588.1_CBS1585 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:32002-33522:+ | gene-YML118W_CBS436 | rna-NM_001182481.1_CBS436 | cds-NP_013588.1_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:26796-28312:+ | gene-YML118W_CBS6412 | rna-NM_001182481.1_CBS6412 | cds-NP_013588.1_CBS6412 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:25260-26776:+ | gene-YML118W_CBS6413 | rna-NM_001182481.1_CBS6413 | cds-NP_013588.1_CBS6413 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:26849-28366:+ | gene-YML118W_CENPK1137D | rna-NM_001182481.1_CENPK1137D | cds-NP_013588.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:26549-28066:+ | gene-YML118W_EthanolRed | rna-NM_001182481.1_EthanolRed | cds-NP_013588.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:26826-28343:+ | gene-YML118W_FaliES1 | rna-NM_001182481.1_FaliES1 | cds-NP_013588.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:61889-63409:- | gene-YML118W_JAY291 | rna-NM_001182481.1_JAY291 | cds-NP_013588.1_JAY291 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:30269-31788:+ | gene-YML118W_MUCL30387 | rna-NM_001182481.1_MUCL30387 | cds-NP_013588.1_MUCL30387 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:33940-35459:+ | gene-YML118W_MUCL30388 | rna-NM_001182481.1_MUCL30388 | cds-NP_013588.1_MUCL30388 | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:26048-27564:+ | gene-YML118W_MUCL39482 | rna-NM_001182481.1_MUCL39482 | cds-NP_013588.1_MUCL39482 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:29712-31231:+ | gene-YML118W_MUCL42920 | rna-NM_001182481.1_MUCL42920 | cds-NP_013588.1_MUCL42920 | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:32288-33805:+ | gene-YML118W_NCIM3186 | rna-NM_001182481.1_NCIM3186 | cds-NP_013588.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:26843-28359:+ | gene-YML118W_NCYC1407 | rna-NM_001182481.1_NCYC1407 | cds-NP_013588.1_NCYC1407 | 99.6 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:32232-33752:+ | gene-YML118W_PE2H3 | rna-NM_001182481.1_PE2H3 | cds-NP_013588.1_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:32170-33690:+ | gene-YML118W_PE2H4 | rna-NM_001182481.1_PE2H4 | cds-NP_013588.1_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:32334-33851:+ | gene-YML118W_S288C | rna-NM_001182481.1_S288C | cds-NP_013588.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:24277-25796:+ | gene-YML118W_SA1 | rna-NM_001182481.1_SA1 | cds-NP_013588.1_SA1 | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:26124-27641:+ | gene-YML118W_ThermosaccDry | rna-NM_001182481.1_ThermosaccDry | cds-NP_013588.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:30521-32041:+ | gene-YML118W_VR1 | rna-NM_001182481.1_VR1 | cds-NP_013588.1_VR1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:5607-7123:+ | gene-YML118W_ZTW1 | rna-NM_001182481.1_ZTW1 | cds-NP_013588.1_ZTW1 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:37144-38656:+ | gene-YML118W_Sparadoxus | rna-NM_001182481.1_Sparadoxus | cds-NP_013588.1_Sparadoxus | 86.6 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |