NGL2 (YMR285C)


Gene profile

Gene name: NGL2
Reference locus (S288C): YMR285C
Gene biotype: protein_coding

Description: RNA exonuclease NGL2; Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p; NGL2 has a paralog, NGL3, that arose from the whole genome duplication

Top 10 interactors (score): REX3 (0.926); REX2 (0.922); NGL1 (0.815); RNH70 (0.807); POP2 (0.783); RRP6 (0.739); MPP6 (0.693); CDC39 (0.633); RAT1 (0.616); MTR4 (0.607); GRC3 (0.577); NOP19 (0.572); CDC36 (0.558); NOB1 (0.543); XRN1 (0.52); RNT1 (0.504); RRP45 (0.49); CAF40 (0.47); RRP40 (0.47); CDC73 (0.459)

Homologues (species, bitscore): ANGEL1 (Homo sapiens, 79.3); Angel1 (Mus musculus, 79.3); LOC569547 (Danio rerio, 89.4); cnot6l (Xenopus tropicalis, 81.6); twin (Drosophila melanogaster, 76.6); ccr-4 (Caenorhabditis elegans, 71.6); AT1G31500 (Arabidopsis thaliana, 89.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:879196-880743:- gene-YMR285C_AKU4011 rna-NM_001182792.1_AKU4011 cds-NP_014012.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:72930-74477:+ gene-YMR285C_BG1 rna-NM_001182792.1_BG1 cds-NP_014012.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:824405-825952:- gene-YMR285C_Bruggeman rna-NM_001182792.1_Bruggeman cds-NP_014012.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:827691-829238:- gene-YMR285C_CAT1 rna-NM_001182792.1_CAT1 cds-NP_014012.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:811446-812993:- gene-YMR285C_CBS1585 rna-NM_001182792.1_CBS1585 cds-NP_014012.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:833761-835308:- gene-YMR285C_CBS436 rna-NM_001182792.1_CBS436 cds-NP_014012.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:923020-924567:- gene-YMR285C_CBS6412 rna-NM_001182792.1_CBS6412 cds-NP_014012.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:810567-812114:- gene-YMR285C_CBS6413 rna-NM_001182792.1_CBS6413 cds-NP_014012.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:834690-836237:- gene-YMR285C_CENPK1137D rna-NM_001182792.1_CENPK1137D cds-NP_014012.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:871886-873433:- gene-YMR285C_EthanolRed rna-NM_001182792.1_EthanolRed cds-NP_014012.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:817913-819460:- gene-YMR285C_FaliES1 rna-NM_001182792.1_FaliES1 cds-NP_014012.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000262.1:32273-33820:+ gene-YMR285C_JAY291 rna-NM_001182792.1_JAY291 cds-NP_014012.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:818230-819777:- gene-YMR285C_MUCL30387 rna-NM_001182792.1_MUCL30387 cds-NP_014012.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:827627-829174:- gene-YMR285C_MUCL30388 rna-NM_001182792.1_MUCL30388 cds-NP_014012.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:812534-814081:- gene-YMR285C_MUCL39482 rna-NM_001182792.1_MUCL39482 cds-NP_014012.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:821338-822885:- gene-YMR285C_MUCL42920 rna-NM_001182792.1_MUCL42920 cds-NP_014012.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:840098-841645:- gene-YMR285C_NCIM3186 rna-NM_001182792.1_NCIM3186 cds-NP_014012.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:812177-813724:- gene-YMR285C_NCYC1407 rna-NM_001182792.1_NCYC1407 cds-NP_014012.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:827982-829529:- gene-YMR285C_PE2H3 rna-NM_001182792.1_PE2H3 cds-NP_014012.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:823956-825503:- gene-YMR285C_PE2H4 rna-NM_001182792.1_PE2H4 cds-NP_014012.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:840144-841691:- gene-YMR285C_S288C rna-NM_001182792.1_S288C cds-NP_014012.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000036.1:17912-19459:- gene-YMR285C_SA1 rna-NM_001182792.1_SA1 cds-NP_014012.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:814082-815629:- gene-YMR285C_ThermosaccDry rna-NM_001182792.1_ThermosaccDry cds-NP_014012.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:827827-829374:- gene-YMR285C_VR1 rna-NM_001182792.1_VR1 cds-NP_014012.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:229316-230863:- gene-YMR285C_ZTW1 rna-NM_001182792.1_ZTW1 cds-NP_014012.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:832690-834237:- gene-YMR285C_Sparadoxus rna-NM_001182792.1_Sparadoxus cds-NP_014012.1_Sparadoxus 89.5 100.0 Verified 1 1 1 False True False False False

Additional files