NFS1 (YCL017C)


Gene profile

Gene name: NFS1
Reference locus (S288C): YCL017C
Gene biotype: protein_coding

Description: Cysteine desulfurase, mitochondrial; Cysteine desulfurase; involved in iron-sulfur cluster (Fe/S) biogenesis and in thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria

Top 10 interactors (score): UBA4 (0.999); ISD11 (0.999); ISU2 (0.999); TUM1 (0.999); YFH1 (0.999); ISU1 (0.999); YAH1 (0.999); NFU1 (0.997); JAC1 (0.997); NCS6 (0.985); ISA1 (0.984); NCS2 (0.98); GRX5 (0.98); ACP1 (0.979); ATM1 (0.977); ISA2 (0.975); IBA57 (0.973); NBP35 (0.966); ARH1 (0.96); URM1 (0.959)

Homologues (species, bitscore): NFS1 (Homo sapiens, 585.1); Nfs1 (Mus musculus, 577.4); nfs1 (Danio rerio, 582.0); nfs1 (Xenopus tropicalis, 565.1); CG12264 (Drosophila melanogaster, 565.1); B0205.6 (Caenorhabditis elegans, 550.1); NFS1 (Arabidopsis thaliana, 540.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:87485-88978:- gene-YCL017C_AKU4011 rna-NM_001178664.1_AKU4011 cds-NP_009912.2_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000178.1:57062-58555:+ gene-YCL017C_BG1 rna-NM_001178664.1_BG1 cds-NP_009912.2_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:82076-83569:- gene-YCL017C_Bruggeman rna-NM_001178664.1_Bruggeman cds-NP_009912.2_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:87289-88782:- gene-YCL017C_CAT1 rna-NM_001178664.1_CAT1 cds-NP_009912.2_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:88134-89627:- gene-YCL017C_CBS1585 rna-NM_001178664.1_CBS1585 cds-NP_009912.2_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:93055-94548:- gene-YCL017C_CBS436 rna-NM_001178664.1_CBS436 cds-NP_009912.2_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:75592-77085:- gene-YCL017C_CBS6412 rna-NM_001178664.1_CBS6412 cds-NP_009912.2_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:87441-88934:- gene-YCL017C_CBS6413 rna-NM_001178664.1_CBS6413 cds-NP_009912.2_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:92244-93747:- gene-YCL017C_CENPK1137D rna-NM_001178664.1_CENPK1137D cds-NP_009912.2_CENPK1137D 99.3 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:85503-86996:- gene-YCL017C_EthanolRed rna-NM_001178664.1_EthanolRed cds-NP_009912.2_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:87793-89286:- gene-YCL017C_FaliES1 rna-NM_001178664.1_FaliES1 cds-NP_009912.2_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000126.1:1970-3463:- gene-YCL017C_JAY291 rna-NM_001178664.1_JAY291 cds-NP_009912.2_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:80512-82005:- gene-YCL017C_MUCL30387 rna-NM_001178664.1_MUCL30387 cds-NP_009912.2_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:80066-81559:- gene-YCL017C_MUCL30388 rna-NM_001178664.1_MUCL30388 cds-NP_009912.2_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:88550-90043:- gene-YCL017C_MUCL39482 rna-NM_001178664.1_MUCL39482 cds-NP_009912.2_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:83787-85280:- gene-YCL017C_MUCL42920 rna-NM_001178664.1_MUCL42920 cds-NP_009912.2_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:92409-93902:- gene-YCL017C_NCIM3186 rna-NM_001178664.1_NCIM3186 cds-NP_009912.2_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:89033-90526:- gene-YCL017C_NCYC1407 rna-NM_001178664.1_NCYC1407 cds-NP_009912.2_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:93207-94700:- gene-YCL017C_PE2H3 rna-NM_001178664.1_PE2H3 cds-NP_009912.2_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:93164-94657:- gene-YCL017C_PE2H4 rna-NM_001178664.1_PE2H4 cds-NP_009912.2_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:92777-94270:- gene-YCL017C_S288C rna-NM_001178664.1_S288C cds-NP_009912.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000073.1:57069-58562:+ gene-YCL017C_SA1 rna-NM_001178664.1_SA1 cds-NP_009912.2_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:88367-89860:- gene-YCL017C_ThermosaccDry rna-NM_001178664.1_ThermosaccDry cds-NP_009912.2_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:99011-100504:- gene-YCL017C_VR1 rna-NM_001178664.1_VR1 cds-NP_009912.2_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:87309-88802:- gene-YCL017C_ZTW1 rna-NM_001178664.1_ZTW1 cds-NP_009912.2_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:117589-119082:- gene-YCL017C_Sparadoxus rna-NM_001178664.1_Sparadoxus cds-NP_009912.2_Sparadoxus 92.5 100.0 Verified 1 1 1 False True False False False

Additional files