NEO1 (YIL048W)


Gene profile

Gene name: NEO1
Reference locus (S288C): YIL048W
Gene biotype: protein_coding

Description: Probable phospholipid-transporting ATPase NEO1; Phospholipid translocase (flippase), role in phospholipid asymmetry of plasma membrane; involved in endocytosis, vacuolar biogenesis and Golgi to ER vesicle-mediated transport; localizes to endosomes and the Golgi apparatus

Top 10 interactors (score): CDC50 (0.97); MON2 (0.965); LEM3 (0.953); DOP1 (0.947); ANY1 (0.942); CWC22 (0.882); YNR048W (0.876); DRS2 (0.874); ARL1 (0.771); DNF2 (0.723); FPK1 (0.712); DNF1 (0.71); SPC3 (0.7); YOR072W (0.699); SEC7 (0.691); CHO1 (0.682); KIN82 (0.671); AIM19 (0.646); VIP1 (0.644); CCR4 (0.644)

Homologues (species, bitscore): ATP9B (Homo sapiens, 1011.9); Atp9b (Mus musculus, 1015.8); atp9b (Danio rerio, 1009.2); atp9a (Xenopus tropicalis, 980.3); CG31729 (Drosophila melanogaster, 963.4); tat-5 (Caenorhabditis elegans, 983.4); ALA3 (Arabidopsis thaliana, 450.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:258270-261725:+ gene-YIL048W_AKU4011 rna-NM_001179398.1_AKU4011 cds-NP_012216.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:119701-123156:+ gene-YIL048W_BG1 rna-NM_001179398.1_BG1 cds-NP_012216.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:264525-267980:+ gene-YIL048W_Bruggeman rna-NM_001179398.1_Bruggeman cds-NP_012216.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:252436-255891:+ gene-YIL048W_CAT1 rna-NM_001179398.1_CAT1 cds-NP_012216.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:258095-261550:+ gene-YIL048W_CBS1585 rna-NM_001179398.1_CBS1585 cds-NP_012216.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:253399-256854:+ gene-YIL048W_CBS436 rna-NM_001179398.1_CBS436 cds-NP_012216.1_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:254710-258165:+ gene-YIL048W_CBS6412 rna-NM_001179398.1_CBS6412 cds-NP_012216.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:250261-253716:+ gene-YIL048W_CBS6413 rna-NM_001179398.1_CBS6413 cds-NP_012216.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:253150-256605:+ gene-YIL048W_CENPK1137D rna-NM_001179398.1_CENPK1137D cds-NP_012216.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:242184-245639:+ gene-YIL048W_EthanolRed rna-NM_001179398.1_EthanolRed cds-NP_012216.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:259723-263178:+ gene-YIL048W_FaliES1 rna-NM_001179398.1_FaliES1 cds-NP_012216.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000365.1:35697-39152:- gene-YIL048W_JAY291 rna-NM_001179398.1_JAY291 cds-NP_012216.1_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:261413-264868:+ gene-YIL048W_MUCL30387 rna-NM_001179398.1_MUCL30387 cds-NP_012216.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:258016-261471:+ gene-YIL048W_MUCL30388 rna-NM_001179398.1_MUCL30388 cds-NP_012216.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:258938-262393:+ gene-YIL048W_MUCL39482 rna-NM_001179398.1_MUCL39482 cds-NP_012216.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:262069-265524:+ gene-YIL048W_MUCL42920 rna-NM_001179398.1_MUCL42920 cds-NP_012216.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:261437-264892:+ gene-YIL048W_NCIM3186 rna-NM_001179398.1_NCIM3186 cds-NP_012216.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:263211-266666:+ gene-YIL048W_NCYC1407 rna-NM_001179398.1_NCYC1407 cds-NP_012216.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:256449-259904:+ gene-YIL048W_PE2H3 rna-NM_001179398.1_PE2H3 cds-NP_012216.1_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:251169-254624:+ gene-YIL048W_PE2H4 rna-NM_001179398.1_PE2H4 cds-NP_012216.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:261437-264892:+ gene-YIL048W_S288C rna-NM_001179398.1_S288C cds-NP_012216.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000031.1:61280-64735:- gene-YIL048W_SA1 rna-NM_001179398.1_SA1 cds-NP_012216.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:258392-261847:+ gene-YIL048W_ThermosaccDry rna-NM_001179398.1_ThermosaccDry cds-NP_012216.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:255565-259020:+ gene-YIL048W_VR1 rna-NM_001179398.1_VR1 cds-NP_012216.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:232235-235690:+ gene-YIL048W_ZTW1 rna-NM_001179398.1_ZTW1 cds-NP_012216.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:254351-257806:+ gene-YIL048W_Sparadoxus rna-NM_001179398.1_Sparadoxus cds-NP_012216.1_Sparadoxus 92.3 99.9 Verified 1 1 1 False True False False False

Additional files