NEM1 (YHR004C)


Gene profile

Gene name: NEM1
Reference locus (S288C): YHR004C
Gene biotype: protein_coding

Description: Nuclear envelope morphology protein 1; Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard; Belongs to the Dullard family

Top 10 interactors (score): SPO7 (0.999); PAH1 (0.993); DGK1 (0.849); ICE2 (0.772); PPH21 (0.759); LPP1 (0.75); DPP1 (0.748); RRD2 (0.748); CDC55 (0.746); GLC7 (0.735); PPH3 (0.734); SDS22 (0.731); TPD3 (0.73); CMP2 (0.728); CNA1 (0.728); CNB1 (0.727); SIT4 (0.725); REG1 (0.721); GIP2 (0.721); REG2 (0.72)

Homologues (species, bitscore): CTDNEP1 (Homo sapiens, 157.1); Ctdnep1 (Mus musculus, 156.8); ctdnep1b (Danio rerio, 158.3); ctdsp2 (Xenopus tropicalis, 128.6); Dd (Drosophila melanogaster, 147.1); scpl-2 (Caenorhabditis elegans, 140.6); SSP4 (Arabidopsis thaliana, 114.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:100357-101697:- gene-YHR004C_AKU4011 rna-NM_001179134.1_AKU4011 cds-NP_011867.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:20073-21413:- gene-YHR004C_BG1 rna-NM_001179134.1_BG1 cds-NP_011867.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:107215-108555:- gene-YHR004C_Bruggeman rna-NM_001179134.1_Bruggeman cds-NP_011867.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:101199-102539:- gene-YHR004C_CAT1 rna-NM_001179134.1_CAT1 cds-NP_011867.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:100944-102284:- gene-YHR004C_CBS1585 rna-NM_001179134.1_CBS1585 cds-NP_011867.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:93446-94786:- gene-YHR004C_CBS436 rna-NM_001179134.1_CBS436 cds-NP_011867.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:100543-101883:- gene-YHR004C_CBS6412 rna-NM_001179134.1_CBS6412 cds-NP_011867.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:100271-101611:- gene-YHR004C_CBS6413 rna-NM_001179134.1_CBS6413 cds-NP_011867.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:104902-106242:- gene-YHR004C_CENPK1137D rna-NM_001179134.1_CENPK1137D cds-NP_011867.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:100353-101693:- gene-YHR004C_EthanolRed rna-NM_001179134.1_EthanolRed cds-NP_011867.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:100882-102222:- gene-YHR004C_FaliES1 rna-NM_001179134.1_FaliES1 cds-NP_011867.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000064.1:19738-21078:+ gene-YHR004C_JAY291 rna-NM_001179134.1_JAY291 cds-NP_011867.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:103955-105295:- gene-YHR004C_MUCL30387 rna-NM_001179134.1_MUCL30387 cds-NP_011867.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:105166-106506:- gene-YHR004C_MUCL30388 rna-NM_001179134.1_MUCL30388 cds-NP_011867.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:99970-101310:- gene-YHR004C_MUCL39482 rna-NM_001179134.1_MUCL39482 cds-NP_011867.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:103875-105215:- gene-YHR004C_MUCL42920 rna-NM_001179134.1_MUCL42920 cds-NP_011867.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:111636-112976:- gene-YHR004C_NCIM3186 rna-NM_001179134.1_NCIM3186 cds-NP_011867.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:99388-100728:- gene-YHR004C_NCYC1407 rna-NM_001179134.1_NCYC1407 cds-NP_011867.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:101592-102932:- gene-YHR004C_PE2H3 rna-NM_001179134.1_PE2H3 cds-NP_011867.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:109033-110373:- gene-YHR004C_PE2H4 rna-NM_001179134.1_PE2H4 cds-NP_011867.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:111754-113094:- gene-YHR004C_S288C rna-NM_001179134.1_S288C cds-NP_011867.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000075.1:33458-34798:+ gene-YHR004C_SA1 rna-NM_001179134.1_SA1 cds-NP_011867.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:101972-103312:- gene-YHR004C_ThermosaccDry rna-NM_001179134.1_ThermosaccDry cds-NP_011867.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:107519-108859:- gene-YHR004C_VR1 rna-NM_001179134.1_VR1 cds-NP_011867.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:93137-94477:- gene-YHR004C_ZTW1 rna-NM_001179134.1_ZTW1 cds-NP_011867.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:99732-101075:- gene-YHR004C_Sparadoxus rna-NM_001179134.1_Sparadoxus cds-NP_011867.1_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files