Gene name: NDC80
Reference locus (S288C): YIL144W
Gene biotype: protein_coding
Description: Component of the kinetochore-associated Ndc80 complex; conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, and kinetochore assembly and clustering; evolutionarily conserved; complex members include Ndc80p, Nuf2p, Scp24p, and Spc25p; modified by sumoylation
Top 10 interactors (score): STU2 (0.999); SPC25 (0.999); SMC1 (0.999); IPL1 (0.999); BUB3 (0.999); NUF2 (0.999); BUB1 (0.998); KIP2 (0.997); SPC24 (0.997); CDC5 (0.996); MPS1 (0.993); MAD3 (0.992); MAD2 (0.991); SMC3 (0.989); SMC2 (0.987); ESP1 (0.986); SPC105 (0.985); SMC4 (0.983); BIM1 (0.982); MTW1 (0.981)
Homologues (species, bitscore): NDC80 (Homo sapiens, 102.4); Ndc80 (Mus musculus, 95.9); ndc80 (Danio rerio, 86.3); ENSXETP00000045005 (Xenopus tropicalis, 67.0); ndc-80 (Caenorhabditis elegans, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:79293-81368:+ | gene-YIL144W_AKU4011 | rna-NM_001179492.3_AKU4011 | cds-NP_012122.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:55995-58070:- | gene-YIL144W_BG1 | rna-NM_001179492.3_BG1 | cds-NP_012122.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:82050-84125:+ | gene-YIL144W_Bruggeman | rna-NM_001179492.3_Bruggeman | cds-NP_012122.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:75862-77937:+ | gene-YIL144W_CAT1 | rna-NM_001179492.3_CAT1 | cds-NP_012122.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:79496-81571:+ | gene-YIL144W_CBS1585 | rna-NM_001179492.3_CBS1585 | cds-NP_012122.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:70636-72711:+ | gene-YIL144W_CBS436 | rna-NM_001179492.3_CBS436 | cds-NP_012122.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:77026-79101:+ | gene-YIL144W_CBS6412 | rna-NM_001179492.3_CBS6412 | cds-NP_012122.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:71181-73256:+ | gene-YIL144W_CBS6413 | rna-NM_001179492.3_CBS6413 | cds-NP_012122.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:69777-71852:+ | gene-YIL144W_CENPK1137D | rna-NM_001179492.3_CENPK1137D | cds-NP_012122.3_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:64829-66904:+ | gene-YIL144W_EthanolRed | rna-NM_001179492.3_EthanolRed | cds-NP_012122.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:80632-82707:+ | gene-YIL144W_FaliES1 | rna-NM_001179492.3_FaliES1 | cds-NP_012122.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000319.1:25647-27722:- | gene-YIL144W_JAY291 | rna-NM_001179492.3_JAY291 | cds-NP_012122.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:79811-81886:+ | gene-YIL144W_MUCL30387 | rna-NM_001179492.3_MUCL30387 | cds-NP_012122.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:79059-81134:+ | gene-YIL144W_MUCL30388 | rna-NM_001179492.3_MUCL30388 | cds-NP_012122.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:80422-82497:+ | gene-YIL144W_MUCL39482 | rna-NM_001179492.3_MUCL39482 | cds-NP_012122.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:83623-85698:+ | gene-YIL144W_MUCL42920 | rna-NM_001179492.3_MUCL42920 | cds-NP_012122.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:78074-80149:+ | gene-YIL144W_NCIM3186 | rna-NM_001179492.3_NCIM3186 | cds-NP_012122.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:84387-86462:+ | gene-YIL144W_NCYC1407 | rna-NM_001179492.3_NCYC1407 | cds-NP_012122.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:79010-81085:+ | gene-YIL144W_PE2H3 | rna-NM_001179492.3_PE2H3 | cds-NP_012122.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:72972-75047:+ | gene-YIL144W_PE2H4 | rna-NM_001179492.3_PE2H4 | cds-NP_012122.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:78074-80149:+ | gene-YIL144W_S288C | rna-NM_001179492.3_S288C | cds-NP_012122.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000050.1:56649-58724:+ | gene-YIL144W_SA1 | rna-NM_001179492.3_SA1 | cds-NP_012122.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:79242-81317:+ | gene-YIL144W_ThermosaccDry | rna-NM_001179492.3_ThermosaccDry | cds-NP_012122.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:76399-78474:+ | gene-YIL144W_VR1 | rna-NM_001179492.3_VR1 | cds-NP_012122.3_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:54223-56298:+ | gene-YIL144W_ZTW1 | rna-NM_001179492.3_ZTW1 | cds-NP_012122.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:72014-74089:+ | gene-YIL144W_Sparadoxus | rna-NM_001179492.3_Sparadoxus | cds-NP_012122.3_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |