Gene name: NCS6
Reference locus (S288C): YGL211W
Gene biotype: protein_coding
Description: Cytoplasmic tRNA 2-thiolation protein 1; Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs; required for the thiolation of uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae
Top 10 interactors (score): NCS2 (0.999); UBA4 (0.997); URM1 (0.996); TUM1 (0.992); ELP3 (0.989); MCM5 (0.988); IKI3 (0.987); NFS1 (0.985); TRM9 (0.984); ELP2 (0.983); TRM112 (0.944); KTI12 (0.935); ELP4 (0.928); ELP6 (0.913); SLM3 (0.873); KTI11 (0.834); ATS1 (0.831); IKI1 (0.815); SIT4 (0.775); AHP1 (0.765)
Homologues (species, bitscore): CTU1 (Homo sapiens, 335.1); Ctu1 (Mus musculus, 317.8); ctu1 (Danio rerio, 409.1); ctu1 (Xenopus tropicalis, 412.1); CG8078 (Drosophila melanogaster, 392.9); tut-1 (Caenorhabditis elegans, 368.2); ROL5 (Arabidopsis thaliana, 378.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:93858-94937:+ | gene-YGL211W_AKU4011 | rna-NM_001181076.1_AKU4011 | cds-NP_011304.2_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:86921-88000:+ | gene-YGL211W_BG1 | rna-NM_001181076.1_BG1 | cds-NP_011304.2_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:94367-95446:+ | gene-YGL211W_Bruggeman | rna-NM_001181076.1_Bruggeman | cds-NP_011304.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:93033-94112:+ | gene-YGL211W_CAT1 | rna-NM_001181076.1_CAT1 | cds-NP_011304.2_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:98163-99242:+ | gene-YGL211W_CBS1585 | rna-NM_001181076.1_CBS1585 | cds-NP_011304.2_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:93728-94807:+ | gene-YGL211W_CBS436 | rna-NM_001181076.1_CBS436 | cds-NP_011304.2_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:85294-86373:+ | gene-YGL211W_CBS6412 | rna-NM_001181076.1_CBS6412 | cds-NP_011304.2_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:91998-93077:+ | gene-YGL211W_CBS6413 | rna-NM_001181076.1_CBS6413 | cds-NP_011304.2_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:92542-93621:+ | gene-YGL211W_CENPK1137D | rna-NM_001181076.1_CENPK1137D | cds-NP_011304.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:84659-85738:+ | gene-YGL211W_EthanolRed | rna-NM_001181076.1_EthanolRed | cds-NP_011304.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:85502-86581:+ | gene-YGL211W_FaliES1 | rna-NM_001181076.1_FaliES1 | cds-NP_011304.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:11910-12990:+ | gene-YGL211W_JAY291 | rna-NM_001181076.1_JAY291 | cds-NP_011304.2_JAY291 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:94282-95361:+ | gene-YGL211W_MUCL30387 | rna-NM_001181076.1_MUCL30387 | cds-NP_011304.2_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:96460-97539:+ | gene-YGL211W_MUCL30388 | rna-NM_001181076.1_MUCL30388 | cds-NP_011304.2_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:94676-95755:+ | gene-YGL211W_MUCL39482 | rna-NM_001181076.1_MUCL39482 | cds-NP_011304.2_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:97780-98859:+ | gene-YGL211W_MUCL42920 | rna-NM_001181076.1_MUCL42920 | cds-NP_011304.2_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:92512-93591:+ | gene-YGL211W_NCIM3186 | rna-NM_001181076.1_NCIM3186 | cds-NP_011304.2_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:86398-87477:+ | gene-YGL211W_NCYC1407 | rna-NM_001181076.1_NCYC1407 | cds-NP_011304.2_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:89226-90305:+ | gene-YGL211W_PE2H3 | rna-NM_001181076.1_PE2H3 | cds-NP_011304.2_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:88774-89853:+ | gene-YGL211W_PE2H4 | rna-NM_001181076.1_PE2H4 | cds-NP_011304.2_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:92512-93591:+ | gene-YGL211W_S288C | rna-NM_001181076.1_S288C | cds-NP_011304.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:281690-282769:- | gene-YGL211W_SA1 | rna-NM_001181076.1_SA1 | cds-NP_011304.2_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:85763-86842:+ | gene-YGL211W_ThermosaccDry | rna-NM_001181076.1_ThermosaccDry | cds-NP_011304.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:93640-94719:+ | gene-YGL211W_VR1 | rna-NM_001181076.1_VR1 | cds-NP_011304.2_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:84803-85882:+ | gene-YGL211W_ZTW1 | rna-NM_001181076.1_ZTW1 | cds-NP_011304.2_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:91945-93024:+ | gene-YGL211W_Sparadoxus | rna-NM_001181076.1_Sparadoxus | cds-NP_011304.2_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |