Gene name: NCS2
Reference locus (S288C): YNL119W
Gene biotype: protein_coding
Description: Cytoplasmic tRNA 2-thiolation protein 2; Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs; required for the thiolation of uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae; Belongs to the CTU2/NCS2 family
Top 10 interactors (score): NCS6 (0.999); URM1 (0.998); UBA4 (0.998); TUM1 (0.991); NFS1 (0.98); IKI3 (0.961); TRM9 (0.961); ELP2 (0.957); ELP3 (0.953); MCM5 (0.953); TRM112 (0.919); ELP6 (0.917); ATS1 (0.856); KTI12 (0.855); ELP4 (0.851); KTI11 (0.815); ACL4 (0.799); SAP185 (0.78); AHP1 (0.777); IMP4 (0.772)
Homologues (species, bitscore): CTU2 (Homo sapiens, 56.6); ctu2 (Danio rerio, 59.3); ctu2 (Xenopus tropicalis, 53.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:394722-396203:+ | gene-YNL119W_AKU4011 | rna-NM_001182957.3_AKU4011 | cds-NP_014280.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:298719-300200:+ | gene-YNL119W_BG1 | rna-NM_001182957.3_BG1 | cds-NP_014280.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:405188-406669:+ | gene-YNL119W_Bruggeman | rna-NM_001182957.3_Bruggeman | cds-NP_014280.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:448488-449969:+ | gene-YNL119W_CAT1 | rna-NM_001182957.3_CAT1 | cds-NP_014280.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:395342-396823:+ | gene-YNL119W_CBS1585 | rna-NM_001182957.3_CBS1585 | cds-NP_014280.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:463754-465235:+ | gene-YNL119W_CBS436 | rna-NM_001182957.3_CBS436 | cds-NP_014280.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:390795-392276:+ | gene-YNL119W_CBS6412 | rna-NM_001182957.3_CBS6412 | cds-NP_014280.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:391760-393241:+ | gene-YNL119W_CBS6413 | rna-NM_001182957.3_CBS6413 | cds-NP_014280.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:394890-396371:+ | gene-YNL119W_CENPK1137D | rna-NM_001182957.3_CENPK1137D | cds-NP_014280.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:391712-393193:+ | gene-YNL119W_EthanolRed | rna-NM_001182957.3_EthanolRed | cds-NP_014280.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:387614-389095:+ | gene-YNL119W_FaliES1 | rna-NM_001182957.3_FaliES1 | cds-NP_014280.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:43996-45477:+ | gene-YNL119W_JAY291 | rna-NM_001182957.3_JAY291 | cds-NP_014280.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:401607-403088:+ | gene-YNL119W_MUCL30387 | rna-NM_001182957.3_MUCL30387 | cds-NP_014280.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:436786-438267:+ | gene-YNL119W_MUCL30388 | rna-NM_001182957.3_MUCL30388 | cds-NP_014280.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:392621-394102:+ | gene-YNL119W_MUCL39482 | rna-NM_001182957.3_MUCL39482 | cds-NP_014280.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:395861-397342:+ | gene-YNL119W_MUCL42920 | rna-NM_001182957.3_MUCL42920 | cds-NP_014280.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:401009-402490:+ | gene-YNL119W_NCIM3186 | rna-NM_001182957.3_NCIM3186 | cds-NP_014280.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:394753-396234:+ | gene-YNL119W_NCYC1407 | rna-NM_001182957.3_NCYC1407 | cds-NP_014280.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:393745-395226:+ | gene-YNL119W_PE2H3 | rna-NM_001182957.3_PE2H3 | cds-NP_014280.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:393151-394632:+ | gene-YNL119W_PE2H4 | rna-NM_001182957.3_PE2H4 | cds-NP_014280.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:401040-402521:+ | gene-YNL119W_S288C | rna-NM_001182957.3_S288C | cds-NP_014280.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:11005-12486:- | gene-YNL119W_SA1 | rna-NM_001182957.3_SA1 | cds-NP_014280.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:388468-389949:+ | gene-YNL119W_ThermosaccDry | rna-NM_001182957.3_ThermosaccDry | cds-NP_014280.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:407134-408615:+ | gene-YNL119W_VR1 | rna-NM_001182957.3_VR1 | cds-NP_014280.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:298301-299782:+ | gene-YNL119W_ZTW1 | rna-NM_001182957.3_ZTW1 | cds-NP_014280.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:399283-400764:+ | gene-YNL119W_Sparadoxus | rna-NM_001182957.3_Sparadoxus | cds-NP_014280.3_Sparadoxus | 88.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |