Gene name: NAT1
Reference locus (S288C): YDL040C
Gene biotype: protein_coding
Description: Subunit of protein N-terminal acetyltransferase NatA; NatA comprised of Nat1p, Ard1p, and Nat5p; N-terminally acetylates many proteins to influence multiple processes such as cell cycle progression, heat-shock resistance, mating, sporulation, telomeric silencing and early stages of mitophagy; orthologous to human NAA15; expression of both human NAA10 and NAA15 functionally complements ard1 nat1 double mutant although single mutations are not complemented by their orthologs
Top 10 interactors (score): NAT5 (0.999); NAT3 (0.999); ARD1 (0.999); MAK3 (0.999); MAK10 (0.994); MDM20 (0.993); MAP2 (0.987); TAF1 (0.96); MAP1 (0.928); MAK31 (0.925); SIR1 (0.871); RPL4A (0.853); RPL16A (0.851); RPL25 (0.845); RPL39 (0.83); RPL31A (0.829); RPL42B (0.818); RPL42A (0.818); RPL15A (0.817); RPL22A (0.815)
Homologues (species, bitscore): NAA15 (Homo sapiens, 323.9); Naa15 (Mus musculus, 328.9); naa15b (Danio rerio, 312.8); naa15 (Xenopus tropicalis, 313.9); Nat1 (Drosophila melanogaster, 322.4); hpo-29 (Caenorhabditis elegans, 278.5); EMB2753 (Arabidopsis thaliana, 345.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:363498-366062:- | gene-YDL040C_AKU4011 | rna-NM_001180099.1_AKU4011 | cds-NP_010244.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:183643-186207:+ | gene-YDL040C_BG1 | rna-NM_001180099.1_BG1 | cds-NP_010244.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:381978-384542:- | gene-YDL040C_Bruggeman | rna-NM_001180099.1_Bruggeman | cds-NP_010244.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:378196-380760:- | gene-YDL040C_CAT1 | rna-NM_001180099.1_CAT1 | cds-NP_010244.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:361748-364312:- | gene-YDL040C_CBS1585 | rna-NM_001180099.1_CBS1585 | cds-NP_010244.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:378415-380979:- | gene-YDL040C_CBS436 | rna-NM_001180099.1_CBS436 | cds-NP_010244.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:359455-362019:- | gene-YDL040C_CBS6412 | rna-NM_001180099.1_CBS6412 | cds-NP_010244.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:379787-382351:- | gene-YDL040C_CBS6413 | rna-NM_001180099.1_CBS6413 | cds-NP_010244.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:377734-380298:- | gene-YDL040C_CENPK1137D | rna-NM_001180099.1_CENPK1137D | cds-NP_010244.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:374281-376845:- | gene-YDL040C_EthanolRed | rna-NM_001180099.1_EthanolRed | cds-NP_010244.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:380509-383073:- | gene-YDL040C_FaliES1 | rna-NM_001180099.1_FaliES1 | cds-NP_010244.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000097.1:2717-5281:+ | gene-YDL040C_JAY291 | rna-NM_001180099.1_JAY291 | cds-NP_010244.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:378645-381209:- | gene-YDL040C_MUCL30387 | rna-NM_001180099.1_MUCL30387 | cds-NP_010244.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:369763-372327:- | gene-YDL040C_MUCL30388 | rna-NM_001180099.1_MUCL30388 | cds-NP_010244.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:362952-365516:- | gene-YDL040C_MUCL39482 | rna-NM_001180099.1_MUCL39482 | cds-NP_010244.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:284868-287432:- | gene-YDL040C_MUCL42920 | rna-NM_001180099.1_MUCL42920 | cds-NP_010244.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:378797-381361:- | gene-YDL040C_NCIM3186 | rna-NM_001180099.1_NCIM3186 | cds-NP_010244.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:362833-365397:- | gene-YDL040C_NCYC1407 | rna-NM_001180099.1_NCYC1407 | cds-NP_010244.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:370006-372570:- | gene-YDL040C_PE2H3 | rna-NM_001180099.1_PE2H3 | cds-NP_010244.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:370008-372572:- | gene-YDL040C_PE2H4 | rna-NM_001180099.1_PE2H4 | cds-NP_010244.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:378874-381438:- | gene-YDL040C_S288C | rna-NM_001180099.1_S288C | cds-NP_010244.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:53490-56054:+ | gene-YDL040C_SA1 | rna-NM_001180099.1_SA1 | cds-NP_010244.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:379971-382535:- | gene-YDL040C_ThermosaccDry | rna-NM_001180099.1_ThermosaccDry | cds-NP_010244.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:382895-385459:- | gene-YDL040C_VR1 | rna-NM_001180099.1_VR1 | cds-NP_010244.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:377912-380476:- | gene-YDL040C_ZTW1 | rna-NM_001180099.1_ZTW1 | cds-NP_010244.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:380340-382910:- | gene-YDL040C_Sparadoxus | rna-NM_001180099.1_Sparadoxus | cds-NP_010244.1_Sparadoxus | 89.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |