NAS6 (YGR232W)


Gene profile

Gene name: NAS6
Reference locus (S288C): YGR232W
Gene biotype: protein_coding

Description: Probable 26S proteasome regulatory subunit p28; Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6

Top 10 interactors (score): RPT1 (0.999); RPT6 (0.999); RPT3 (0.999); RPT4 (0.999); RPT2 (0.999); RPN14 (0.999); RPT5 (0.999); RPN9 (0.999); RPN10 (0.999); RPN11 (0.999); RPN1 (0.999); RPN3 (0.998); RPN8 (0.997); RPN5 (0.997); RPN6 (0.997); NAS2 (0.996); HSM3 (0.993); RPN7 (0.992); RPN13 (0.983); RPN2 (0.98)

Homologues (species, bitscore): PSMD10 (Homo sapiens, 114.8); Psmd10 (Mus musculus, 112.8); psmd10 (Danio rerio, 128.6); psmd10 (Xenopus tropicalis, 108.2); Tnks (Drosophila melanogaster, 86.7); F40G9.17 (Caenorhabditis elegans, 94.7); AT2G03430 (Arabidopsis thaliana, 122.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:919362-920048:+ gene-YGR232W_AKU4011 rna-NM_001181361.3_AKU4011 cds-NP_011748.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:199477-200166:+ gene-YGR232W_BG1 rna-NM_001181361.3_BG1 cds-NP_011748.3_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:926958-927647:+ gene-YGR232W_Bruggeman rna-NM_001181361.3_Bruggeman cds-NP_011748.3_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:925657-926343:+ gene-YGR232W_CAT1 rna-NM_001181361.3_CAT1 cds-NP_011748.3_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:922226-922912:+ gene-YGR232W_CBS1585 rna-NM_001181361.3_CBS1585 cds-NP_011748.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:925884-926573:+ gene-YGR232W_CBS436 rna-NM_001181361.3_CBS436 cds-NP_011748.3_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:913096-913782:+ gene-YGR232W_CBS6412 rna-NM_001181361.3_CBS6412 cds-NP_011748.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:919155-919841:+ gene-YGR232W_CBS6413 rna-NM_001181361.3_CBS6413 cds-NP_011748.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:953607-954293:+ gene-YGR232W_CENPK1137D rna-NM_001181361.3_CENPK1137D cds-NP_011748.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:907365-908051:+ gene-YGR232W_EthanolRed rna-NM_001181361.3_EthanolRed cds-NP_011748.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:912000-912686:+ gene-YGR232W_FaliES1 rna-NM_001181361.3_FaliES1 cds-NP_011748.3_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:117589-118275:- gene-YGR232W_JAY291 rna-NM_001181361.3_JAY291 cds-NP_011748.3_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:924874-925563:+ gene-YGR232W_MUCL30387 rna-NM_001181361.3_MUCL30387 cds-NP_011748.3_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:924128-924817:+ gene-YGR232W_MUCL30388 rna-NM_001181361.3_MUCL30388 cds-NP_011748.3_MUCL30388 98.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:917301-917987:+ gene-YGR232W_MUCL39482 rna-NM_001181361.3_MUCL39482 cds-NP_011748.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:935852-936538:+ gene-YGR232W_MUCL42920 rna-NM_001181361.3_MUCL42920 cds-NP_011748.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:953960-954646:+ gene-YGR232W_NCIM3186 rna-NM_001181361.3_NCIM3186 cds-NP_011748.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:912958-913644:+ gene-YGR232W_NCYC1407 rna-NM_001181361.3_NCYC1407 cds-NP_011748.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:938155-938844:+ gene-YGR232W_PE2H3 rna-NM_001181361.3_PE2H3 cds-NP_011748.3_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:942994-943683:+ gene-YGR232W_PE2H4 rna-NM_001181361.3_PE2H4 cds-NP_011748.3_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:953960-954646:+ gene-YGR232W_S288C rna-NM_001181361.3_S288C cds-NP_011748.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:46842-47531:- gene-YGR232W_SA1 rna-NM_001181361.3_SA1 cds-NP_011748.3_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:932511-933197:+ gene-YGR232W_ThermosaccDry rna-NM_001181361.3_ThermosaccDry cds-NP_011748.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1037300-1037986:+ gene-YGR232W_VR1 rna-NM_001181361.3_VR1 cds-NP_011748.3_VR1 98.9 100.0 Verified 1 1 0 False False True False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:233943-234629:+ gene-YGR232W_ZTW1 rna-NM_001181361.3_ZTW1 cds-NP_011748.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:924708-925394:+ gene-YGR232W_Sparadoxus rna-NM_001181361.3_Sparadoxus cds-NP_011748.3_Sparadoxus 91.9 100.0 Verified 1 1 1 False True False False False

Additional files