NAS2 (YIL007C)


Gene profile

Gene name: NAS2
Reference locus (S288C): YIL007C
Gene biotype: protein_coding

Description: Probable 26S proteasome regulatory subunit p27; Evolutionarily conserved 19S regulatory particle assembly-chaperone; involved in assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); non-essential gene; interacts with Rpn4p; protein abundance increases in response to DNA replication stress; ortholog of human p27; Belongs to the proteasome subunit p27 family

Top 10 interactors (score): RPT1 (0.999); RPT4 (0.999); RPT5 (0.999); RPT6 (0.998); RPT3 (0.998); NAS6 (0.996); RPT2 (0.996); RPN2 (0.995); HSM3 (0.993); RPN1 (0.988); RPN5 (0.988); RPN14 (0.986); RPN10 (0.983); RPN6 (0.977); PRE1 (0.974); RPN3 (0.97); RPN11 (0.966); PRE10 (0.966); PRE7 (0.963); PRE9 (0.962)

Homologues (species, bitscore): PSMD9 (Homo sapiens, 127.1); Psmd9 (Mus musculus, 125.9); psmd9 (Danio rerio, 127.1); psmd9 (Xenopus tropicalis, 127.5); CG9588 (Drosophila melanogaster, 77.8); psmd-9 (Caenorhabditis elegans, 92.0); AT5G57950 (Arabidopsis thaliana, 71.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:342323-342985:- gene-YIL007C_AKU4011 rna-NM_001179357.3_AKU4011 cds-NP_012259.3_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000072.1:83555-84217:+ gene-YIL007C_BG1 rna-NM_001179357.3_BG1 cds-NP_012259.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:346848-347510:- gene-YIL007C_Bruggeman rna-NM_001179357.3_Bruggeman cds-NP_012259.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:333491-334153:- gene-YIL007C_CAT1 rna-NM_001179357.3_CAT1 cds-NP_012259.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:342396-343058:- gene-YIL007C_CBS1585 rna-NM_001179357.3_CBS1585 cds-NP_012259.3_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:335124-335786:- gene-YIL007C_CBS436 rna-NM_001179357.3_CBS436 cds-NP_012259.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:337802-338464:- gene-YIL007C_CBS6412 rna-NM_001179357.3_CBS6412 cds-NP_012259.3_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:334483-335145:- gene-YIL007C_CBS6413 rna-NM_001179357.3_CBS6413 cds-NP_012259.3_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:335055-335717:- gene-YIL007C_CENPK1137D rna-NM_001179357.3_CENPK1137D cds-NP_012259.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:325436-326098:- gene-YIL007C_EthanolRed rna-NM_001179357.3_EthanolRed cds-NP_012259.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:343682-344344:- gene-YIL007C_FaliES1 rna-NM_001179357.3_FaliES1 cds-NP_012259.3_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000009.1:47137-47799:+ gene-YIL007C_JAY291 rna-NM_001179357.3_JAY291 cds-NP_012259.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:344020-344682:- gene-YIL007C_MUCL30387 rna-NM_001179357.3_MUCL30387 cds-NP_012259.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:340768-341430:- gene-YIL007C_MUCL30388 rna-NM_001179357.3_MUCL30388 cds-NP_012259.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:343012-343674:- gene-YIL007C_MUCL39482 rna-NM_001179357.3_MUCL39482 cds-NP_012259.3_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:346650-347312:- gene-YIL007C_MUCL42920 rna-NM_001179357.3_MUCL42920 cds-NP_012259.3_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:342994-343656:- gene-YIL007C_NCIM3186 rna-NM_001179357.3_NCIM3186 cds-NP_012259.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:347280-347942:- gene-YIL007C_NCYC1407 rna-NM_001179357.3_NCYC1407 cds-NP_012259.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:337069-337731:- gene-YIL007C_PE2H3 rna-NM_001179357.3_PE2H3 cds-NP_012259.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:331775-332437:- gene-YIL007C_PE2H4 rna-NM_001179357.3_PE2H4 cds-NP_012259.3_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:342994-343656:- gene-YIL007C_S288C rna-NM_001179357.3_S288C cds-NP_012259.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000066.1:17820-18482:- gene-YIL007C_SA1 rna-NM_001179357.3_SA1 cds-NP_012259.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:341787-342449:- gene-YIL007C_ThermosaccDry rna-NM_001179357.3_ThermosaccDry cds-NP_012259.3_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:337630-338292:- gene-YIL007C_VR1 rna-NM_001179357.3_VR1 cds-NP_012259.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:315790-316452:- gene-YIL007C_ZTW1 rna-NM_001179357.3_ZTW1 cds-NP_012259.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:337162-337824:- gene-YIL007C_Sparadoxus rna-NM_001179357.3_Sparadoxus cds-NP_012259.3_Sparadoxus 88.6 100.0 Verified 1 1 1 False True False False False

Additional files