NAP1 (YKR048C)


Gene profile

Gene name: NAP1
Reference locus (S288C): YKR048C
Gene biotype: protein_coding

Description: Nucleosome assembly protein; Histone chaperone; involved in histone exchange by removing and replacing histone H2A-H2B dimers or histone variant dimers from assembled nucleosomes; involved in the transport of H2A and H2B histones to the nucleus; required for the regulation of microtubule dynamics during mitosis; interacts with mitotic cyclin Clb2p; controls bud morphogenesis; phosphorylated by CK2; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): HTA1 (0.999); HTA2 (0.999); HTZ1 (0.999); VPS75 (0.997); HTB2 (0.997); HTB1 (0.995); KAP114 (0.995); ASF1 (0.979); CKA2 (0.977); UTP5 (0.973); CLB2 (0.971); CKA1 (0.966); TIF11 (0.965); CKB2 (0.964); KCC4 (0.961); NIS1 (0.958); GIN4 (0.943); NBA1 (0.942); SDA1 (0.939); CHZ1 (0.925)

Homologues (species, bitscore): NAP1L1 (Homo sapiens, 203.4); Nap1l1 (Mus musculus, 204.1); nap1l1 (Danio rerio, 212.6); nap1l1 (Xenopus tropicalis, 209.9); Nap1 (Drosophila melanogaster, 172.2); nap-1 (Caenorhabditis elegans, 156.4); NAP1;1 (Arabidopsis thaliana, 194.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:510682-511935:- gene-YKR048C_AKU4011 rna-NM_001179838.1_AKU4011 cds-NP_012974.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:131589-132842:+ gene-YKR048C_BG1 rna-NM_001179838.1_BG1 cds-NP_012974.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:532861-534114:- gene-YKR048C_Bruggeman rna-NM_001179838.1_Bruggeman cds-NP_012974.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:529283-530536:- gene-YKR048C_CAT1 rna-NM_001179838.1_CAT1 cds-NP_012974.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:523423-524676:- gene-YKR048C_CBS1585 rna-NM_001179838.1_CBS1585 cds-NP_012974.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:522256-523509:- gene-YKR048C_CBS436 rna-NM_001179838.1_CBS436 cds-NP_012974.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:507600-508853:- gene-YKR048C_CBS6412 rna-NM_001179838.1_CBS6412 cds-NP_012974.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:523242-524495:- gene-YKR048C_CBS6413 rna-NM_001179838.1_CBS6413 cds-NP_012974.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:525043-526296:- gene-YKR048C_CENPK1137D rna-NM_001179838.1_CENPK1137D cds-NP_012974.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:521003-522256:- gene-YKR048C_EthanolRed rna-NM_001179838.1_EthanolRed cds-NP_012974.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:524140-525393:- gene-YKR048C_FaliES1 rna-NM_001179838.1_FaliES1 cds-NP_012974.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000077.1:28406-29659:+ gene-YKR048C_JAY291 rna-NM_001179838.1_JAY291 cds-NP_012974.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:533259-534512:- gene-YKR048C_MUCL30387 rna-NM_001179838.1_MUCL30387 cds-NP_012974.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:527622-528875:- gene-YKR048C_MUCL30388 rna-NM_001179838.1_MUCL30388 cds-NP_012974.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:522750-524003:- gene-YKR048C_MUCL39482 rna-NM_001179838.1_MUCL39482 cds-NP_012974.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:528775-530028:- gene-YKR048C_MUCL42920 rna-NM_001179838.1_MUCL42920 cds-NP_012974.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:525376-526629:- gene-YKR048C_NCIM3186 rna-NM_001179838.1_NCIM3186 cds-NP_012974.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:522964-524217:- gene-YKR048C_NCYC1407 rna-NM_001179838.1_NCYC1407 cds-NP_012974.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:548329-549582:- gene-YKR048C_PE2H3 rna-NM_001179838.1_PE2H3 cds-NP_012974.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:532727-533980:- gene-YKR048C_PE2H4 rna-NM_001179838.1_PE2H4 cds-NP_012974.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:525387-526640:- gene-YKR048C_S288C rna-NM_001179838.1_S288C cds-NP_012974.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000093.1:8488-9741:- gene-YKR048C_SA1 rna-NM_001179838.1_SA1 cds-NP_012974.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:523379-524632:- gene-YKR048C_ThermosaccDry rna-NM_001179838.1_ThermosaccDry cds-NP_012974.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:523398-524651:- gene-YKR048C_VR1 rna-NM_001179838.1_VR1 cds-NP_012974.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:521400-522653:- gene-YKR048C_ZTW1 rna-NM_001179838.1_ZTW1 cds-NP_012974.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:546810-548063:- gene-YKR048C_Sparadoxus rna-NM_001179838.1_Sparadoxus cds-NP_012974.1_Sparadoxus 91.6 100.0 Verified 1 1 1 False True False False False

Additional files