NAM8 (YHR086W)


Gene profile

Gene name: NAM8
Reference locus (S288C): YHR086W
Gene biotype: protein_coding

Description: RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function

Top 10 interactors (score): SNU66 (0.999); PRP39 (0.999); MUD1 (0.999); SNU71 (0.999); LEA1 (0.999); YHC1 (0.999); LUC7 (0.999); SNU56 (0.999); PRP42 (0.999); SNP1 (0.999); PRP40 (0.999); SMD3 (0.999); SMD1 (0.998); RSE1 (0.998); CBC2 (0.998); MUD2 (0.998); SMD2 (0.998); SMB1 (0.998); HSH155 (0.998); SME1 (0.997)

Homologues (species, bitscore): TIA1 (Homo sapiens, 119.0); Tia1 (Mus musculus, 122.5); tia1l (Danio rerio, 119.0); tia1 (Xenopus tropicalis, 116.7); CG15440 (Drosophila melanogaster, 99.0); tiar-1 (Caenorhabditis elegans, 98.2); RBP45B (Arabidopsis thaliana, 182.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:264562-266133:+ gene-YHR086W_AKU4011 rna-NM_001179216.1_AKU4011 cds-NP_011954.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:184910-186481:+ gene-YHR086W_BG1 rna-NM_001179216.1_BG1 cds-NP_011954.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:272389-273960:+ gene-YHR086W_Bruggeman rna-NM_001179216.1_Bruggeman cds-NP_011954.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:267530-269101:+ gene-YHR086W_CAT1 rna-NM_001179216.1_CAT1 cds-NP_011954.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:263604-265175:+ gene-YHR086W_CBS1585 rna-NM_001179216.1_CBS1585 cds-NP_011954.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:261468-263039:+ gene-YHR086W_CBS436 rna-NM_001179216.1_CBS436 cds-NP_011954.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:266952-268523:+ gene-YHR086W_CBS6412 rna-NM_001179216.1_CBS6412 cds-NP_011954.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:264643-266214:+ gene-YHR086W_CBS6413 rna-NM_001179216.1_CBS6413 cds-NP_011954.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:271320-272891:+ gene-YHR086W_CENPK1137D rna-NM_001179216.1_CENPK1137D cds-NP_011954.1_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:324168-325739:+ gene-YHR086W_EthanolRed rna-NM_001179216.1_EthanolRed cds-NP_011954.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:264972-266543:+ gene-YHR086W_FaliES1 rna-NM_001179216.1_FaliES1 cds-NP_011954.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000394.1:47697-49268:+ gene-YHR086W_JAY291 rna-NM_001179216.1_JAY291 cds-NP_011954.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:271910-273481:+ gene-YHR086W_MUCL30387 rna-NM_001179216.1_MUCL30387 cds-NP_011954.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:271772-273343:+ gene-YHR086W_MUCL30388 rna-NM_001179216.1_MUCL30388 cds-NP_011954.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:263927-265498:+ gene-YHR086W_MUCL39482 rna-NM_001179216.1_MUCL39482 cds-NP_011954.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:270675-272246:+ gene-YHR086W_MUCL42920 rna-NM_001179216.1_MUCL42920 cds-NP_011954.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:278035-279606:+ gene-YHR086W_NCIM3186 rna-NM_001179216.1_NCIM3186 cds-NP_011954.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:266392-267963:+ gene-YHR086W_NCYC1407 rna-NM_001179216.1_NCYC1407 cds-NP_011954.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:266062-267633:+ gene-YHR086W_PE2H3 rna-NM_001179216.1_PE2H3 cds-NP_011954.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:273509-275080:+ gene-YHR086W_PE2H4 rna-NM_001179216.1_PE2H4 cds-NP_011954.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:278153-279724:+ gene-YHR086W_S288C rna-NM_001179216.1_S288C cds-NP_011954.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:79264-80835:- gene-YHR086W_SA1 rna-NM_001179216.1_SA1 cds-NP_011954.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:266063-267634:+ gene-YHR086W_ThermosaccDry rna-NM_001179216.1_ThermosaccDry cds-NP_011954.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:273937-275508:+ gene-YHR086W_VR1 rna-NM_001179216.1_VR1 cds-NP_011954.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:257616-259188:+ gene-YHR086W_ZTW1 rna-NM_001179216.1_ZTW1 cds-NP_011954.1_ZTW1 99.4 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:263376-264947:+ gene-YHR086W_Sparadoxus rna-NM_001179216.1_Sparadoxus cds-NP_011954.1_Sparadoxus 89.4 99.8 Verified 1 1 1 False True False False False

Additional files