Gene name: NAM7
Reference locus (S288C): YMR080C
Gene biotype: protein_coding
Description: ATP-dependent RNA helicase of the SFI superfamily; involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; binds to the small ribosomal subunit via an interaction with Rps26; forms cytoplasmic foci upon DNA replication stress
Top 10 interactors (score): SUP35 (0.999); NMD2 (0.999); XRN1 (0.999); UPF3 (0.999); FAL1 (0.998); SUP45 (0.998); STO1 (0.996); DCP2 (0.996); PAB1 (0.996); EBS1 (0.992); SKI7 (0.987); EST1 (0.978); EDC3 (0.974); LSM1 (0.973); DHH1 (0.97); CBC2 (0.965); DCP1 (0.955); RRP6 (0.954); CDC33 (0.947); NMD3 (0.916)
Homologues (species, bitscore): UPF1 (Homo sapiens, 965.7); Upf1 (Mus musculus, 966.5); upf1 (Danio rerio, 970.7); upf1 (Xenopus tropicalis, 750.4); Upf1 (Drosophila melanogaster, 931.0); smg-2 (Caenorhabditis elegans, 808.5); LBA1 (Arabidopsis thaliana, 959.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:464660-467575:- | gene-YMR080C_AKU4011 | rna-NM_001182579.1_AKU4011 | cds-NP_013797.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:75451-78366:+ | gene-YMR080C_BG1 | rna-NM_001182579.1_BG1 | cds-NP_013797.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:406837-409752:- | gene-YMR080C_Bruggeman | rna-NM_001182579.1_Bruggeman | cds-NP_013797.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:407152-410067:- | gene-YMR080C_CAT1 | rna-NM_001182579.1_CAT1 | cds-NP_013797.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:397600-400515:- | gene-YMR080C_CBS1585 | rna-NM_001182579.1_CBS1585 | cds-NP_013797.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:402913-405828:- | gene-YMR080C_CBS436 | rna-NM_001182579.1_CBS436 | cds-NP_013797.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:510674-513589:- | gene-YMR080C_CBS6412 | rna-NM_001182579.1_CBS6412 | cds-NP_013797.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:396858-399773:- | gene-YMR080C_CBS6413 | rna-NM_001182579.1_CBS6413 | cds-NP_013797.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:420816-423731:- | gene-YMR080C_CENPK1137D | rna-NM_001182579.1_CENPK1137D | cds-NP_013797.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:397491-400406:- | gene-YMR080C_EthanolRed | rna-NM_001182579.1_EthanolRed | cds-NP_013797.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:400657-403572:- | gene-YMR080C_FaliES1 | rna-NM_001182579.1_FaliES1 | cds-NP_013797.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:33652-36567:+ | gene-YMR080C_JAY291 | rna-NM_001182579.1_JAY291 | cds-NP_013797.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:402571-405486:- | gene-YMR080C_MUCL30387 | rna-NM_001182579.1_MUCL30387 | cds-NP_013797.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:407257-410172:- | gene-YMR080C_MUCL30388 | rna-NM_001182579.1_MUCL30388 | cds-NP_013797.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:397888-400803:- | gene-YMR080C_MUCL39482 | rna-NM_001182579.1_MUCL39482 | cds-NP_013797.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:404574-407489:- | gene-YMR080C_MUCL42920 | rna-NM_001182579.1_MUCL42920 | cds-NP_013797.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:426666-429581:- | gene-YMR080C_NCIM3186 | rna-NM_001182579.1_NCIM3186 | cds-NP_013797.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:397803-400718:- | gene-YMR080C_NCYC1407 | rna-NM_001182579.1_NCYC1407 | cds-NP_013797.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:403512-406427:- | gene-YMR080C_PE2H3 | rna-NM_001182579.1_PE2H3 | cds-NP_013797.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:409607-412522:- | gene-YMR080C_PE2H4 | rna-NM_001182579.1_PE2H4 | cds-NP_013797.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:426712-429627:- | gene-YMR080C_S288C | rna-NM_001182579.1_S288C | cds-NP_013797.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:120540-123455:+ | gene-YMR080C_SA1 | rna-NM_001182579.1_SA1 | cds-NP_013797.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:398460-401375:- | gene-YMR080C_ThermosaccDry | rna-NM_001182579.1_ThermosaccDry | cds-NP_013797.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:410096-413011:- | gene-YMR080C_VR1 | rna-NM_001182579.1_VR1 | cds-NP_013797.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:374735-377650:- | gene-YMR080C_ZTW1 | rna-NM_001182579.1_ZTW1 | cds-NP_013797.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:411132-414047:- | gene-YMR080C_Sparadoxus | rna-NM_001182579.1_Sparadoxus | cds-NP_013797.1_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |