Gene name: NAB2
Reference locus (S288C): YGL122C
Gene biotype: protein_coding
Description: Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family
Top 10 interactors (score): GFD1 (0.999); YRA1 (0.997); MEX67 (0.996); KAP104 (0.996); GLE1 (0.987); MLP1 (0.985); NPL3 (0.983); RRP6 (0.97); SUB2 (0.956); PAB1 (0.955); HRP1 (0.953); CBC2 (0.951); DBP5 (0.945); MUD2 (0.928); PCF11 (0.928); NUP42 (0.926); THO2 (0.882); MLP2 (0.878); SGN1 (0.87); NUP159 (0.868)
Homologues (species, bitscore): ZC3H14 (Homo sapiens, 66.6); Zc3h14 (Mus musculus, 57.0); zc3h14 (Danio rerio, 55.5); ZC3H14 (Xenopus tropicalis, 56.2); NFAT (Drosophila melanogaster, 54.3); sut-2 (Caenorhabditis elegans, 57.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:281759-283273:- | gene-YGL122C_AKU4011 | rna-NM_001180987.3_AKU4011 | cds-NP_011393.3_AKU4011 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:121889-123397:+ | gene-YGL122C_BG1 | rna-NM_001180987.3_BG1 | cds-NP_011393.3_BG1 | 95.1 | 95.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:284465-286018:- | gene-YGL122C_Bruggeman | rna-NM_001180987.3_Bruggeman | cds-NP_011393.3_Bruggeman | 98.4 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:280043-281536:- | gene-YGL122C_CAT1 | rna-NM_001180987.3_CAT1 | cds-NP_011393.3_CAT1 | 94.5 | 94.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:285085-286599:- | gene-YGL122C_CBS1585 | rna-NM_001180987.3_CBS1585 | cds-NP_011393.3_CBS1585 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:279996-281489:- | gene-YGL122C_CBS436 | rna-NM_001180987.3_CBS436 | cds-NP_011393.3_CBS436 | 94.6 | 94.6 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:270362-271876:- | gene-YGL122C_CBS6412 | rna-NM_001180987.3_CBS6412 | cds-NP_011393.3_CBS6412 | 95.2 | 95.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:279962-281476:- | gene-YGL122C_CBS6413 | rna-NM_001180987.3_CBS6413 | cds-NP_011393.3_CBS6413 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:279205-280710:- | gene-YGL122C_CENPK1137D | rna-NM_001180987.3_CENPK1137D | cds-NP_011393.3_CENPK1137D | 95.4 | 95.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:271283-272797:- | gene-YGL122C_EthanolRed | rna-NM_001180987.3_EthanolRed | cds-NP_011393.3_EthanolRed | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:273464-274978:- | gene-YGL122C_FaliES1 | rna-NM_001180987.3_FaliES1 | cds-NP_011393.3_FaliES1 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000046.1:26660-28168:+ | gene-YGL122C_JAY291 | rna-NM_001180987.3_JAY291 | cds-NP_011393.3_JAY291 | 95.1 | 95.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:281435-282988:- | gene-YGL122C_MUCL30387 | rna-NM_001180987.3_MUCL30387 | cds-NP_011393.3_MUCL30387 | 98.4 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:284551-286080:- | gene-YGL122C_MUCL30388 | rna-NM_001180987.3_MUCL30388 | cds-NP_011393.3_MUCL30388 | 96.8 | 96.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:282182-283696:- | gene-YGL122C_MUCL39482 | rna-NM_001180987.3_MUCL39482 | cds-NP_011393.3_MUCL39482 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:285427-286980:- | gene-YGL122C_MUCL42920 | rna-NM_001180987.3_MUCL42920 | cds-NP_011393.3_MUCL42920 | 98.4 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:278946-280523:- | gene-YGL122C_NCIM3186 | rna-NM_001180987.3_NCIM3186 | cds-NP_011393.3_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:273672-275186:- | gene-YGL122C_NCYC1407 | rna-NM_001180987.3_NCYC1407 | cds-NP_011393.3_NCYC1407 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:275062-276570:- | gene-YGL122C_PE2H3 | rna-NM_001180987.3_PE2H3 | cds-NP_011393.3_PE2H3 | 95.1 | 95.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:280060-281568:- | gene-YGL122C_PE2H4 | rna-NM_001180987.3_PE2H4 | cds-NP_011393.3_PE2H4 | 95.1 | 95.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:278946-280523:- | gene-YGL122C_S288C | rna-NM_001180987.3_S288C | cds-NP_011393.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000064.1:23828-25321:- | gene-YGL122C_SA1 | rna-NM_001180987.3_SA1 | cds-NP_011393.3_SA1 | 94.6 | 94.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:273676-275190:- | gene-YGL122C_ThermosaccDry | rna-NM_001180987.3_ThermosaccDry | cds-NP_011393.3_ThermosaccDry | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:383789-385297:- | gene-YGL122C_VR1 | rna-NM_001180987.3_VR1 | cds-NP_011393.3_VR1 | 95.1 | 95.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:271244-272758:- | gene-YGL122C_ZTW1 | rna-NM_001180987.3_ZTW1 | cds-NP_011393.3_ZTW1 | 95.2 | 95.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:277260-278756:- | gene-YGL122C_Sparadoxus | rna-NM_001180987.3_Sparadoxus | cds-NP_011393.3_Sparadoxus | 81.9 | 93.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |