MYO3 (YKL129C)


Gene profile

Gene name: MYO3
Reference locus (S288C): YKL129C
Gene biotype: protein_coding

Description: Myosin-3; One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO3 has a paralog, MYO5, that arose from the whole genome duplication; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family

Top 10 interactors (score): LAS17 (0.999); VRP1 (0.997); CMD1 (0.995); BBC1 (0.988); ARP2 (0.986); BZZ1 (0.979); SHE4 (0.978); ACT1 (0.962); ABP1 (0.949); PAN1 (0.943); MYO5 (0.922); RVS167 (0.913); SAC6 (0.912); END3 (0.9); SLA2 (0.887); YSC84 (0.875); HOF1 (0.86); BNR1 (0.851); CLC1 (0.845); CRN1 (0.844)

Homologues (species, bitscore): MYO1F (Homo sapiens, 761.1); Myo1e (Mus musculus, 765.4); myo1f (Danio rerio, 770.0); myo1f (Xenopus tropicalis, 722.6); Myo61F (Drosophila melanogaster, 581.3); hum-1 (Caenorhabditis elegans, 704.5); XID (Arabidopsis thaliana, 475.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:183248-187060:- gene-YKL129C_AKU4011 rna-NM_001179695.2_AKU4011 cds-NP_012793.2_AKU4011 99.2 99.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:160403-164215:- gene-YKL129C_BG1 rna-NM_001179695.2_BG1 cds-NP_012793.2_BG1 99.5 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:200910-204722:- gene-YKL129C_Bruggeman rna-NM_001179695.2_Bruggeman cds-NP_012793.2_Bruggeman 99.2 99.8 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:196229-200041:- gene-YKL129C_CAT1 rna-NM_001179695.2_CAT1 cds-NP_012793.2_CAT1 99.3 99.8 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:195496-199308:- gene-YKL129C_CBS1585 rna-NM_001179695.2_CBS1585 cds-NP_012793.2_CBS1585 99.3 99.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:194081-197893:- gene-YKL129C_CBS436 rna-NM_001179695.2_CBS436 cds-NP_012793.2_CBS436 99.5 99.8 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:180121-183933:- gene-YKL129C_CBS6412 rna-NM_001179695.2_CBS6412 cds-NP_012793.2_CBS6412 99.3 99.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:195944-199756:- gene-YKL129C_CBS6413 rna-NM_001179695.2_CBS6413 cds-NP_012793.2_CBS6413 99.3 99.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:195990-199808:- gene-YKL129C_CENPK1137D rna-NM_001179695.2_CENPK1137D cds-NP_012793.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:193980-197792:- gene-YKL129C_EthanolRed rna-NM_001179695.2_EthanolRed cds-NP_012793.2_EthanolRed 99.3 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:194793-198605:- gene-YKL129C_FaliES1 rna-NM_001179695.2_FaliES1 cds-NP_012793.2_FaliES1 99.3 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:17115-20927:- gene-YKL129C_JAY291 rna-NM_001179695.2_JAY291 cds-NP_012793.2_JAY291 99.6 99.8 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:203003-206815:- gene-YKL129C_MUCL30387 rna-NM_001179695.2_MUCL30387 cds-NP_012793.2_MUCL30387 99.3 99.8 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:197360-201172:- gene-YKL129C_MUCL30388 rna-NM_001179695.2_MUCL30388 cds-NP_012793.2_MUCL30388 99.3 99.8 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:195274-199086:- gene-YKL129C_MUCL39482 rna-NM_001179695.2_MUCL39482 cds-NP_012793.2_MUCL39482 99.3 99.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:199662-203474:- gene-YKL129C_MUCL42920 rna-NM_001179695.2_MUCL42920 cds-NP_012793.2_MUCL42920 99.5 99.8 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:196338-200156:- gene-YKL129C_NCIM3186 rna-NM_001179695.2_NCIM3186 cds-NP_012793.2_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:195467-199279:- gene-YKL129C_NCYC1407 rna-NM_001179695.2_NCYC1407 cds-NP_012793.2_NCYC1407 99.3 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:202583-206395:- gene-YKL129C_PE2H3 rna-NM_001179695.2_PE2H3 cds-NP_012793.2_PE2H3 99.5 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:198871-202683:- gene-YKL129C_PE2H4 rna-NM_001179695.2_PE2H4 cds-NP_012793.2_PE2H4 99.6 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:196349-200167:- gene-YKL129C_S288C rna-NM_001179695.2_S288C cds-NP_012793.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:112810-116622:- gene-YKL129C_SA1 rna-NM_001179695.2_SA1 cds-NP_012793.2_SA1 99.6 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:195493-199305:- gene-YKL129C_ThermosaccDry rna-NM_001179695.2_ThermosaccDry cds-NP_012793.2_ThermosaccDry 99.3 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:194840-198652:- gene-YKL129C_VR1 rna-NM_001179695.2_VR1 cds-NP_012793.2_VR1 99.5 99.8 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:194025-197837:- gene-YKL129C_ZTW1 rna-NM_001179695.2_ZTW1 cds-NP_012793.2_ZTW1 99.3 99.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:210723-214532:- gene-YKL129C_Sparadoxus rna-NM_001179695.2_Sparadoxus cds-NP_012793.2_Sparadoxus 89.7 99.6 Verified 1 1 1 False True False False False

Additional files