MXR1 (YER042W)


Gene profile

Gene name: MXR1
Reference locus (S288C): YER042W
Gene biotype: protein_coding

Description: Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease

Top 10 interactors (score): MXR2 (0.999); TRX2 (0.979); YNK1 (0.979); YKL069W (0.971); UGA1 (0.97); AIM45 (0.967); FUM1 (0.963); MET14 (0.867); AAT1 (0.846); HYR1 (0.827); MSY1 (0.826); YHR112C (0.824); TSA2 (0.813); TSA1 (0.792); YOL118C (0.747); TRX1 (0.735); FMP40 (0.734); CTA1 (0.721); ADR1 (0.72); YEL008W (0.718)

Homologues (species, bitscore): MSRA (Homo sapiens, 107.1); Msra (Mus musculus, 108.2); im:7149628 (Danio rerio, 107.5); msra.1 (Xenopus tropicalis, 105.5); Eip71CD (Drosophila melanogaster, 69.3); msra-1 (Caenorhabditis elegans, 65.9); PMSR1 (Arabidopsis thaliana, 109.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:228993-229547:+ gene-YER042W_AKU4011 rna-NM_001178933.1_AKU4011 cds-NP_010960.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:196164-196718:- gene-YER042W_BG1 rna-NM_001178933.1_BG1 cds-NP_010960.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:237851-238405:+ gene-YER042W_Bruggeman rna-NM_001178933.1_Bruggeman cds-NP_010960.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:231964-232518:+ gene-YER042W_CAT1 rna-NM_001178933.1_CAT1 cds-NP_010960.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:228902-229456:+ gene-YER042W_CBS1585 rna-NM_001178933.1_CBS1585 cds-NP_010960.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:230851-231405:+ gene-YER042W_CBS436 rna-NM_001178933.1_CBS436 cds-NP_010960.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:228763-229317:+ gene-YER042W_CBS6412 rna-NM_001178933.1_CBS6412 cds-NP_010960.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:234373-234927:+ gene-YER042W_CBS6413 rna-NM_001178933.1_CBS6413 cds-NP_010960.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:233129-233683:+ gene-YER042W_CENPK1137D rna-NM_001178933.1_CENPK1137D cds-NP_010960.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:229597-230151:+ gene-YER042W_EthanolRed rna-NM_001178933.1_EthanolRed cds-NP_010960.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:229860-230414:+ gene-YER042W_FaliES1 rna-NM_001178933.1_FaliES1 cds-NP_010960.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000192.1:27628-28182:+ gene-YER042W_JAY291 rna-NM_001178933.1_JAY291 cds-NP_010960.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:233302-233856:+ gene-YER042W_MUCL30387 rna-NM_001178933.1_MUCL30387 cds-NP_010960.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:229518-230072:+ gene-YER042W_MUCL30388 rna-NM_001178933.1_MUCL30388 cds-NP_010960.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:227944-228498:+ gene-YER042W_MUCL39482 rna-NM_001178933.1_MUCL39482 cds-NP_010960.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:235020-235574:+ gene-YER042W_MUCL42920 rna-NM_001178933.1_MUCL42920 cds-NP_010960.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:234936-235490:+ gene-YER042W_NCIM3186 rna-NM_001178933.1_NCIM3186 cds-NP_010960.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:233006-233560:+ gene-YER042W_NCYC1407 rna-NM_001178933.1_NCYC1407 cds-NP_010960.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:243640-244194:+ gene-YER042W_PE2H3 rna-NM_001178933.1_PE2H3 cds-NP_010960.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:233581-234135:+ gene-YER042W_PE2H4 rna-NM_001178933.1_PE2H4 cds-NP_010960.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:234937-235491:+ gene-YER042W_S288C rna-NM_001178933.1_S288C cds-NP_010960.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:8198-8752:- gene-YER042W_SA1 rna-NM_001178933.1_SA1 cds-NP_010960.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:230632-231186:+ gene-YER042W_ThermosaccDry rna-NM_001178933.1_ThermosaccDry cds-NP_010960.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:229736-230290:+ gene-YER042W_VR1 rna-NM_001178933.1_VR1 cds-NP_010960.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:227842-228396:+ gene-YER042W_ZTW1 rna-NM_001178933.1_ZTW1 cds-NP_010960.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:231666-232220:+ gene-YER042W_Sparadoxus rna-NM_001178933.1_Sparadoxus cds-NP_010960.1_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files