Gene name: MVP1
Reference locus (S288C): YMR004W
Gene biotype: protein_coding
Description: Sorting nexin MVP1; Protein required for sorting proteins to the vacuole; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): VPS35 (0.987); VPS29 (0.951); SNX3 (0.945); VPS17 (0.927); VPS5 (0.906); PEP8 (0.899); VPS1 (0.891); MRL1 (0.834); PEP1 (0.769); TMN2 (0.768); YPT35 (0.748); SNX41 (0.721); MSH3 (0.706); ARL1 (0.647); VPS36 (0.645); VMA6 (0.639); VMA4 (0.629); ATG20 (0.623); SNF8 (0.623); SYS1 (0.62)
Homologues (species, bitscore): SNX8 (Homo sapiens, 99.8); Snx8 (Mus musculus, 105.5); snx8a (Danio rerio, 102.1); snx4 (Xenopus tropicalis, 65.9); SH3PX1 (Drosophila melanogaster, 57.8); lst-4 (Caenorhabditis elegans, 54.7); SNX1 (Arabidopsis thaliana, 58.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:323633-325168:+ | gene-YMR004W_AKU4011 | rna-NM_001182500.1_AKU4011 | cds-NP_013717.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:217701-219236:- | gene-YMR004W_BG1 | rna-NM_001182500.1_BG1 | cds-NP_013717.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:263574-265109:+ | gene-YMR004W_Bruggeman | rna-NM_001182500.1_Bruggeman | cds-NP_013717.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:266070-267605:+ | gene-YMR004W_CAT1 | rna-NM_001182500.1_CAT1 | cds-NP_013717.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:256574-258109:+ | gene-YMR004W_CBS1585 | rna-NM_001182500.1_CBS1585 | cds-NP_013717.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:262113-263648:+ | gene-YMR004W_CBS436 | rna-NM_001182500.1_CBS436 | cds-NP_013717.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:369978-371513:+ | gene-YMR004W_CBS6412 | rna-NM_001182500.1_CBS6412 | cds-NP_013717.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:255830-257365:+ | gene-YMR004W_CBS6413 | rna-NM_001182500.1_CBS6413 | cds-NP_013717.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:268748-270283:+ | gene-YMR004W_CENPK1137D | rna-NM_001182500.1_CENPK1137D | cds-NP_013717.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:256381-257916:+ | gene-YMR004W_EthanolRed | rna-NM_001182500.1_EthanolRed | cds-NP_013717.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:259567-261102:+ | gene-YMR004W_FaliES1 | rna-NM_001182500.1_FaliES1 | cds-NP_013717.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:175834-177369:- | gene-YMR004W_JAY291 | rna-NM_001182500.1_JAY291 | cds-NP_013717.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:261301-262836:+ | gene-YMR004W_MUCL30387 | rna-NM_001182500.1_MUCL30387 | cds-NP_013717.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:265964-267499:+ | gene-YMR004W_MUCL30388 | rna-NM_001182500.1_MUCL30388 | cds-NP_013717.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:256859-258394:+ | gene-YMR004W_MUCL39482 | rna-NM_001182500.1_MUCL39482 | cds-NP_013717.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:262417-263952:+ | gene-YMR004W_MUCL42920 | rna-NM_001182500.1_MUCL42920 | cds-NP_013717.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:273971-275506:+ | gene-YMR004W_NCIM3186 | rna-NM_001182500.1_NCIM3186 | cds-NP_013717.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:256776-258311:+ | gene-YMR004W_NCYC1407 | rna-NM_001182500.1_NCYC1407 | cds-NP_013717.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:262704-264239:+ | gene-YMR004W_PE2H3 | rna-NM_001182500.1_PE2H3 | cds-NP_013717.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:268799-270334:+ | gene-YMR004W_PE2H4 | rna-NM_001182500.1_PE2H4 | cds-NP_013717.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:274017-275552:+ | gene-YMR004W_S288C | rna-NM_001182500.1_S288C | cds-NP_013717.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:262721-264256:- | gene-YMR004W_SA1 | rna-NM_001182500.1_SA1 | cds-NP_013717.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:256632-258167:+ | gene-YMR004W_ThermosaccDry | rna-NM_001182500.1_ThermosaccDry | cds-NP_013717.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:260591-262126:+ | gene-YMR004W_VR1 | rna-NM_001182500.1_VR1 | cds-NP_013717.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:235690-237225:+ | gene-YMR004W_ZTW1 | rna-NM_001182500.1_ZTW1 | cds-NP_013717.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:268145-269680:+ | gene-YMR004W_Sparadoxus | rna-NM_001182500.1_Sparadoxus | cds-NP_013717.1_Sparadoxus | 90.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |