MVD1 (YNR043W)


Gene profile

Gene name: MVD1
Reference locus (S288C): YNR043W
Gene biotype: protein_coding

Description: Mevalonate pyrophosphate decarboxylase; essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer; Belongs to the diphosphomevalonate decarboxylase family

Top 10 interactors (score): ERG20 (0.999); ERG8 (0.999); ERG13 (0.999); ERG12 (0.999); IDI1 (0.999); ERG7 (0.994); ERG10 (0.994); ERG9 (0.993); BTS1 (0.992); ERG11 (0.988); UBX3 (0.962); ERG25 (0.959); HMG1 (0.941); ERG1 (0.939); HMG2 (0.938); ERG6 (0.92); COQ1 (0.885); ERG4 (0.856); ERG3 (0.853); ERG27 (0.837)

Homologues (species, bitscore): MVD (Homo sapiens, 348.6); Mvd (Mus musculus, 357.5); mvda (Danio rerio, 335.5); mvd (Xenopus tropicalis, 350.9); CG8239 (Drosophila melanogaster, 332.4); Y48B6A.13 (Caenorhabditis elegans, 255.0); MVD1 (Arabidopsis thaliana, 335.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:685542-686732:+ gene-YNR043W_AKU4011 rna-NM_001183220.1_AKU4011 cds-NP_014441.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:593456-594646:+ gene-YNR043W_BG1 rna-NM_001183220.1_BG1 cds-NP_014441.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:702992-704182:+ gene-YNR043W_Bruggeman rna-NM_001183220.1_Bruggeman cds-NP_014441.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:737257-738447:+ gene-YNR043W_CAT1 rna-NM_001183220.1_CAT1 cds-NP_014441.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:691315-692505:+ gene-YNR043W_CBS1585 rna-NM_001183220.1_CBS1585 cds-NP_014441.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:752958-754148:+ gene-YNR043W_CBS436 rna-NM_001183220.1_CBS436 cds-NP_014441.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:680482-681672:+ gene-YNR043W_CBS6412 rna-NM_001183220.1_CBS6412 cds-NP_014441.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:682188-683378:+ gene-YNR043W_CBS6413 rna-NM_001183220.1_CBS6413 cds-NP_014441.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:695644-696834:+ gene-YNR043W_CENPK1137D rna-NM_001183220.1_CENPK1137D cds-NP_014441.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:687209-688399:+ gene-YNR043W_EthanolRed rna-NM_001183220.1_EthanolRed cds-NP_014441.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:678412-679602:+ gene-YNR043W_FaliES1 rna-NM_001183220.1_FaliES1 cds-NP_014441.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000037.1:23147-24337:- gene-YNR043W_JAY291 rna-NM_001183220.1_JAY291 cds-NP_014441.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:700751-701941:+ gene-YNR043W_MUCL30387 rna-NM_001183220.1_MUCL30387 cds-NP_014441.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:741570-742760:+ gene-YNR043W_MUCL30388 rna-NM_001183220.1_MUCL30388 cds-NP_014441.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:682784-683974:+ gene-YNR043W_MUCL39482 rna-NM_001183220.1_MUCL39482 cds-NP_014441.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:686955-688145:+ gene-YNR043W_MUCL42920 rna-NM_001183220.1_MUCL42920 cds-NP_014441.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:701864-703054:+ gene-YNR043W_NCIM3186 rna-NM_001183220.1_NCIM3186 cds-NP_014441.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:685302-686492:+ gene-YNR043W_NCYC1407 rna-NM_001183220.1_NCYC1407 cds-NP_014441.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:686392-687582:+ gene-YNR043W_PE2H3 rna-NM_001183220.1_PE2H3 cds-NP_014441.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:687710-688900:+ gene-YNR043W_PE2H4 rna-NM_001183220.1_PE2H4 cds-NP_014441.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:701895-703085:+ gene-YNR043W_S288C rna-NM_001183220.1_S288C cds-NP_014441.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000074.1:23295-24485:- gene-YNR043W_SA1 rna-NM_001183220.1_SA1 cds-NP_014441.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:678749-679939:+ gene-YNR043W_ThermosaccDry rna-NM_001183220.1_ThermosaccDry cds-NP_014441.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:720768-721958:+ gene-YNR043W_VR1 rna-NM_001183220.1_VR1 cds-NP_014441.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:588151-589341:+ gene-YNR043W_ZTW1 rna-NM_001183220.1_ZTW1 cds-NP_014441.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:692828-694018:+ gene-YNR043W_Sparadoxus rna-NM_001183220.1_Sparadoxus cds-NP_014441.1_Sparadoxus 91.7 100.0 Unannotated 1 1 0 False False False False True

Additional files