Gene name: MUK1
Reference locus (S288C): YPL070W
Gene biotype: protein_coding
Description: Protein MUK1; Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain
Top 10 interactors (score): YPT52 (0.988); VPS9 (0.978); GDI1 (0.9); YPT10 (0.9); MRS6 (0.9); VPS21 (0.882); YML003W (0.813); ADY3 (0.804); ILV1 (0.794); GCD7 (0.778); YIP3 (0.777); YHL018W (0.77); YPT53 (0.769); VPS5 (0.765); YJL218W (0.756); VPS35 (0.749); YML002W (0.748); YNR014W (0.748); SFH1 (0.745); CDD1 (0.743)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:398669-400507:+ | gene-YPL070W_AKU4011 | rna-NM_001183884.1_AKU4011 | cds-NP_015255.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:604350-606188:+ | gene-YPL070W_BG1 | rna-NM_001183884.1_BG1 | cds-NP_015255.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:474997-476835:+ | gene-YPL070W_Bruggeman | rna-NM_001183884.1_Bruggeman | cds-NP_015255.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:515357-517195:+ | gene-YPL070W_CAT1 | rna-NM_001183884.1_CAT1 | cds-NP_015255.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:402742-404580:+ | gene-YPL070W_CBS1585 | rna-NM_001183884.1_CBS1585 | cds-NP_015255.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:417301-419139:+ | gene-YPL070W_CBS436 | rna-NM_001183884.1_CBS436 | cds-NP_015255.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:406931-408769:+ | gene-YPL070W_CBS6412 | rna-NM_001183884.1_CBS6412 | cds-NP_015255.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:399294-401132:+ | gene-YPL070W_CBS6413 | rna-NM_001183884.1_CBS6413 | cds-NP_015255.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:420917-422755:+ | gene-YPL070W_CENPK1137D | rna-NM_001183884.1_CENPK1137D | cds-NP_015255.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:397035-398873:+ | gene-YPL070W_EthanolRed | rna-NM_001183884.1_EthanolRed | cds-NP_015255.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:404865-406703:+ | gene-YPL070W_FaliES1 | rna-NM_001183884.1_FaliES1 | cds-NP_015255.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:13469-15307:+ | gene-YPL070W_JAY291 | rna-NM_001183884.1_JAY291 | cds-NP_015255.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:415827-417665:+ | gene-YPL070W_MUCL30387 | rna-NM_001183884.1_MUCL30387 | cds-NP_015255.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:414914-416752:+ | gene-YPL070W_MUCL30388 | rna-NM_001183884.1_MUCL30388 | cds-NP_015255.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:396071-397909:+ | gene-YPL070W_MUCL39482 | rna-NM_001183884.1_MUCL39482 | cds-NP_015255.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:453935-455773:+ | gene-YPL070W_MUCL42920 | rna-NM_001183884.1_MUCL42920 | cds-NP_015255.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:420931-422769:+ | gene-YPL070W_NCIM3186 | rna-NM_001183884.1_NCIM3186 | cds-NP_015255.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:403355-405193:+ | gene-YPL070W_NCYC1407 | rna-NM_001183884.1_NCYC1407 | cds-NP_015255.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:409961-411799:+ | gene-YPL070W_PE2H3 | rna-NM_001183884.1_PE2H3 | cds-NP_015255.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:409584-411422:+ | gene-YPL070W_PE2H4 | rna-NM_001183884.1_PE2H4 | cds-NP_015255.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:420948-422786:+ | gene-YPL070W_S288C | rna-NM_001183884.1_S288C | cds-NP_015255.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000057.1:43059-44897:+ | gene-YPL070W_SA1 | rna-NM_001183884.1_SA1 | cds-NP_015255.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:404665-406503:+ | gene-YPL070W_ThermosaccDry | rna-NM_001183884.1_ThermosaccDry | cds-NP_015255.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:419670-421508:+ | gene-YPL070W_VR1 | rna-NM_001183884.1_VR1 | cds-NP_015255.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:403976-405815:+ | gene-YPL070W_ZTW1 | rna-NM_001183884.1_ZTW1 | cds-NP_015255.1_ZTW1 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:405685-407523:+ | gene-YPL070W_Sparadoxus | rna-NM_001183884.1_Sparadoxus | cds-NP_015255.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |