Gene name: MTO1
Reference locus (S288C): YGL236C
Gene biotype: protein_coding
Description: Mitochondrial protein; forms heterodimer complex with Mss1p that performs 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants; human homolog MTO1 can complement yeast null mutant; Belongs to the MnmG family
Top 10 interactors (score): SLM3 (0.999); MSS1 (0.998); TUF1 (0.837); PUS1 (0.836); SPC97 (0.8); ATP6 (0.794); COB (0.769); OLI1 (0.769); PUF3 (0.764); AIM45 (0.722); MTG2 (0.709); VPS45 (0.707); FMT1 (0.701); MSS18 (0.699); GUF1 (0.698); NCL1 (0.697); YNR040W (0.692); QRI7 (0.661); AI5_ALPHA (0.652); RIB2 (0.618)
Homologues (species, bitscore): MTO1 (Homo sapiens, 557.4); Mto1 (Mus musculus, 581.3); mto1 (Danio rerio, 558.5); CG4610 (Drosophila melanogaster, 550.1); F52H3.2 (Caenorhabditis elegans, 497.7); AT2G13440 (Arabidopsis thaliana, 451.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:55320-57329:- | gene-YGL236C_AKU4011 | rna-NM_001181102.1_AKU4011 | cds-NP_011278.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:47355-49364:- | gene-YGL236C_BG1 | rna-NM_001181102.1_BG1 | cds-NP_011278.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:55676-57685:- | gene-YGL236C_Bruggeman | rna-NM_001181102.1_Bruggeman | cds-NP_011278.2_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:53742-55751:- | gene-YGL236C_CAT1 | rna-NM_001181102.1_CAT1 | cds-NP_011278.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:59608-61617:- | gene-YGL236C_CBS1585 | rna-NM_001181102.1_CBS1585 | cds-NP_011278.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:54326-56335:- | gene-YGL236C_CBS436 | rna-NM_001181102.1_CBS436 | cds-NP_011278.2_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:47177-49186:- | gene-YGL236C_CBS6412 | rna-NM_001181102.1_CBS6412 | cds-NP_011278.2_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:53468-55477:- | gene-YGL236C_CBS6413 | rna-NM_001181102.1_CBS6413 | cds-NP_011278.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:53464-55473:- | gene-YGL236C_CENPK1137D | rna-NM_001181102.1_CENPK1137D | cds-NP_011278.2_CENPK1137D | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:46408-48417:- | gene-YGL236C_EthanolRed | rna-NM_001181102.1_EthanolRed | cds-NP_011278.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:46993-49002:- | gene-YGL236C_FaliES1 | rna-NM_001181102.1_FaliES1 | cds-NP_011278.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:18124-20133:+ | gene-YGL236C_JAY291 | rna-NM_001181102.1_JAY291 | cds-NP_011278.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:55603-57612:- | gene-YGL236C_MUCL30387 | rna-NM_001181102.1_MUCL30387 | cds-NP_011278.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:57766-59775:- | gene-YGL236C_MUCL30388 | rna-NM_001181102.1_MUCL30388 | cds-NP_011278.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:56205-58214:- | gene-YGL236C_MUCL39482 | rna-NM_001181102.1_MUCL39482 | cds-NP_011278.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:59087-61096:- | gene-YGL236C_MUCL42920 | rna-NM_001181102.1_MUCL42920 | cds-NP_011278.2_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:53787-55796:- | gene-YGL236C_NCIM3186 | rna-NM_001181102.1_NCIM3186 | cds-NP_011278.2_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:47965-49974:- | gene-YGL236C_NCYC1407 | rna-NM_001181102.1_NCYC1407 | cds-NP_011278.2_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:49821-51830:- | gene-YGL236C_PE2H3 | rna-NM_001181102.1_PE2H3 | cds-NP_011278.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:49369-51378:- | gene-YGL236C_PE2H4 | rna-NM_001181102.1_PE2H4 | cds-NP_011278.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:53787-55796:- | gene-YGL236C_S288C | rna-NM_001181102.1_S288C | cds-NP_011278.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:319534-321543:+ | gene-YGL236C_SA1 | rna-NM_001181102.1_SA1 | cds-NP_011278.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:47299-49308:- | gene-YGL236C_ThermosaccDry | rna-NM_001181102.1_ThermosaccDry | cds-NP_011278.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:54257-56266:- | gene-YGL236C_VR1 | rna-NM_001181102.1_VR1 | cds-NP_011278.2_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:46344-48353:- | gene-YGL236C_ZTW1 | rna-NM_001181102.1_ZTW1 | cds-NP_011278.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:54991-57000:- | gene-YGL236C_Sparadoxus | rna-NM_001181102.1_Sparadoxus | cds-NP_011278.2_Sparadoxus | 89.1 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |