MTM1 (YGR257C)


Gene profile

Gene name: MTM1
Reference locus (S288C): YGR257C
Gene biotype: protein_coding

Description: Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5'-phosphate (PLP) transporter, important for delivery of PLP cofactor to mitochondrial enzymes; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential manganese cofactor

Top 10 interactors (score): SMF2 (0.93); SOD2 (0.902); YGR237C (0.894); YMR1 (0.85); HEM1 (0.812); ATM1 (0.777); ISA1 (0.764); GRX5 (0.749); GGC1 (0.746); PUF3 (0.673); HEM4 (0.664); YJR085C (0.656); YFR045W (0.656); HEM12 (0.654); YAH1 (0.634); ISA2 (0.628); YHR045W (0.619); HEM3 (0.608); HEM2 (0.602); YMC2 (0.6)

Homologues (species, bitscore): SLC25A39 (Homo sapiens, 178.3); Slc25a39 (Mus musculus, 183.3); slc25a39 (Danio rerio, 208.8); slc25a40 (Xenopus tropicalis, 189.1); Shawn (Drosophila melanogaster, 180.6); C16C10.1 (Caenorhabditis elegans, 171.0); AT2G46320 (Arabidopsis thaliana, 159.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:971643-972743:- gene-YGR257C_AKU4011 rna-NM_001181386.3_AKU4011 cds-NP_011773.3_AKU4011 98.9 99.9 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:251805-252905:- gene-YGR257C_BG1 rna-NM_001181386.3_BG1 cds-NP_011773.3_BG1 99.4 99.9 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:980155-981255:- gene-YGR257C_Bruggeman rna-NM_001181386.3_Bruggeman cds-NP_011773.3_Bruggeman 99.3 99.9 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:979098-980198:- gene-YGR257C_CAT1 rna-NM_001181386.3_CAT1 cds-NP_011773.3_CAT1 99.0 99.9 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:974513-975613:- gene-YGR257C_CBS1585 rna-NM_001181386.3_CBS1585 cds-NP_011773.3_CBS1585 98.9 99.9 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:978135-979235:- gene-YGR257C_CBS436 rna-NM_001181386.3_CBS436 cds-NP_011773.3_CBS436 99.3 99.9 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:965403-966503:- gene-YGR257C_CBS6412 rna-NM_001181386.3_CBS6412 cds-NP_011773.3_CBS6412 98.9 99.9 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:971458-972558:- gene-YGR257C_CBS6413 rna-NM_001181386.3_CBS6413 cds-NP_011773.3_CBS6413 98.9 99.9 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:1005886-1006986:- gene-YGR257C_CENPK1137D rna-NM_001181386.3_CENPK1137D cds-NP_011773.3_CENPK1137D 99.7 99.9 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:959486-960586:- gene-YGR257C_EthanolRed rna-NM_001181386.3_EthanolRed cds-NP_011773.3_EthanolRed 99.0 99.9 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:964292-965392:- gene-YGR257C_FaliES1 rna-NM_001181386.3_FaliES1 cds-NP_011773.3_FaliES1 99.0 99.9 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:64919-66019:+ gene-YGR257C_JAY291 rna-NM_001181386.3_JAY291 cds-NP_011773.3_JAY291 99.3 99.9 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:977896-978996:- gene-YGR257C_MUCL30387 rna-NM_001181386.3_MUCL30387 cds-NP_011773.3_MUCL30387 99.3 99.9 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:976030-977130:- gene-YGR257C_MUCL30388 rna-NM_001181386.3_MUCL30388 cds-NP_011773.3_MUCL30388 99.3 99.9 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:969619-970719:- gene-YGR257C_MUCL39482 rna-NM_001181386.3_MUCL39482 cds-NP_011773.3_MUCL39482 98.9 99.9 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:987484-988584:- gene-YGR257C_MUCL42920 rna-NM_001181386.3_MUCL42920 cds-NP_011773.3_MUCL42920 99.1 99.9 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:1006205-1007305:- gene-YGR257C_NCIM3186 rna-NM_001181386.3_NCIM3186 cds-NP_011773.3_NCIM3186 98.5 99.9 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:965248-966348:- gene-YGR257C_NCYC1407 rna-NM_001181386.3_NCYC1407 cds-NP_011773.3_NCYC1407 98.9 99.9 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:990428-991528:- gene-YGR257C_PE2H3 rna-NM_001181386.3_PE2H3 cds-NP_011773.3_PE2H3 99.2 99.9 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:995267-996367:- gene-YGR257C_PE2H4 rna-NM_001181386.3_PE2H4 cds-NP_011773.3_PE2H4 99.2 99.9 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:1006205-1007305:- gene-YGR257C_S288C rna-NM_001181386.3_S288C cds-NP_011773.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000063.1:4425-5525:- gene-YGR257C_SA1 rna-NM_001181386.3_SA1 cds-NP_011773.3_SA1 99.3 99.9 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:984812-985912:- gene-YGR257C_ThermosaccDry rna-NM_001181386.3_ThermosaccDry cds-NP_011773.3_ThermosaccDry 99.0 99.9 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1090591-1091691:- gene-YGR257C_VR1 rna-NM_001181386.3_VR1 cds-NP_011773.3_VR1 99.3 99.9 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:286232-287332:- gene-YGR257C_ZTW1 rna-NM_001181386.3_ZTW1 cds-NP_011773.3_ZTW1 99.0 99.9 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:976787-977887:- gene-YGR257C_Sparadoxus rna-NM_001181386.3_Sparadoxus cds-NP_011773.3_Sparadoxus 91.3 99.8 Verified 1 1 1 False True False False False

Additional files