MTL1 (YGR023W)


Gene profile

Gene name: MTL1
Reference locus (S288C): YGR023W
Gene biotype: protein_coding

Description: Protein MTL1; Putative plasma membrane sensor; involved in cell integrity signaling and stress response during glucose starvation and oxidative stress; has structural and functional similarity to Mid2p; MTL1 has a paralog, MID2, that arose from the whole genome duplication

Top 10 interactors (score): ROM2 (0.978); SLG1 (0.952); ROM1 (0.941); MID2 (0.939); WSC3 (0.913); WSC2 (0.892); RHO1 (0.888); BCK1 (0.813); PKC1 (0.779); MKK1 (0.766); SLT2 (0.76); RLM1 (0.747); TOR1 (0.718); MKK2 (0.712); RAS2 (0.683); SWI4 (0.654); HEK2 (0.63); KDX1 (0.611); WSC4 (0.569); SWI6 (0.561)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:531107-532810:+ gene-YGR023W_AKU4011 rna-NM_001181152.1_AKU4011 cds-NP_011537.1_AKU4011 95.8 99.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000060.1:43079-44803:- gene-YGR023W_BG1 rna-NM_001181152.1_BG1 cds-NP_011537.1_BG1 95.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:532289-534274:+ gene-YGR023W_Bruggeman rna-NM_001181152.1_Bruggeman cds-NP_011537.1_Bruggeman 82.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:531068-533101:+ gene-YGR023W_CAT1 rna-NM_001181152.1_CAT1 cds-NP_011537.1_CAT1 80.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:532426-534135:+ gene-YGR023W_CBS1585 rna-NM_001181152.1_CBS1585 cds-NP_011537.1_CBS1585 95.6 99.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:527172-528896:+ gene-YGR023W_CBS436 rna-NM_001181152.1_CBS436 cds-NP_011537.1_CBS436 95.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:525196-526899:+ gene-YGR023W_CBS6412 rna-NM_001181152.1_CBS6412 cds-NP_011537.1_CBS6412 95.8 99.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:529276-530985:+ gene-YGR023W_CBS6413 rna-NM_001181152.1_CBS6413 cds-NP_011537.1_CBS6413 95.5 99.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:529079-530818:+ gene-YGR023W_CENPK1137D rna-NM_001181152.1_CENPK1137D cds-NP_011537.1_CENPK1137D 95.1 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:519299-521020:+ gene-YGR023W_EthanolRed rna-NM_001181152.1_EthanolRed cds-NP_011537.1_EthanolRed 94.7 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:522548-524506:+ gene-YGR023W_FaliES1 rna-NM_001181152.1_FaliES1 cds-NP_011537.1_FaliES1 83.3 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000020.1:61455-63188:+ gene-YGR023W_JAY291 rna-NM_001181152.1_JAY291 cds-NP_011537.1_JAY291 94.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:529516-531185:+ gene-YGR023W_MUCL30387 rna-NM_001181152.1_MUCL30387 cds-NP_011537.1_MUCL30387 93.1 99.9 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:532059-533798:+ gene-YGR023W_MUCL30388 rna-NM_001181152.1_MUCL30388 cds-NP_011537.1_MUCL30388 94.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:528254-529963:+ gene-YGR023W_MUCL39482 rna-NM_001181152.1_MUCL39482 cds-NP_011537.1_MUCL39482 95.6 99.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:537999-539723:+ gene-YGR023W_MUCL42920 rna-NM_001181152.1_MUCL42920 cds-NP_011537.1_MUCL42920 95.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:529264-530919:+ gene-YGR023W_NCIM3186 rna-NM_001181152.1_NCIM3186 cds-NP_011537.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:522437-524146:+ gene-YGR023W_NCYC1407 rna-NM_001181152.1_NCYC1407 cds-NP_011537.1_NCYC1407 95.3 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:525329-527005:+ gene-YGR023W_PE2H3 rna-NM_001181152.1_PE2H3 cds-NP_011537.1_PE2H3 97.3 99.6 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:530379-532112:+ gene-YGR023W_PE2H4 rna-NM_001181152.1_PE2H4 cds-NP_011537.1_PE2H4 94.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:529264-530919:+ gene-YGR023W_S288C rna-NM_001181152.1_S288C cds-NP_011537.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000021.1:24712-26436:- gene-YGR023W_SA1 rna-NM_001181152.1_SA1 cds-NP_011537.1_SA1 95.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:541875-543845:+ gene-YGR023W_ThermosaccDry rna-NM_001181152.1_ThermosaccDry cds-NP_011537.1_ThermosaccDry 82.9 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:632547-634271:+ gene-YGR023W_VR1 rna-NM_001181152.1_VR1 cds-NP_011537.1_VR1 95.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:520801-522516:+ gene-YGR023W_ZTW1 rna-NM_001181152.1_ZTW1 cds-NP_011537.1_ZTW1 95.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:530203-531915:+ gene-YGR023W_Sparadoxus rna-NM_001181152.1_Sparadoxus cds-NP_011537.1_Sparadoxus 80.1 97.8 Verified 1 1 1 False True False False False

Additional files