MSP1 (YGR028W)


Gene profile

Gene name: MSP1
Reference locus (S288C): YGR028W
Gene biotype: protein_coding

Description: Protein MSP1; Highly-conserved N-terminally anchored AAA-ATPase; distributed in the mitochondrial outer membrane and peroxisomes; involved in mitochondrial protein sorting; functions as an extraction engine in local organelle surveillance to remove and initiate degradation of mistargeted proteins, ensuring fidelity of organelle-specific localization of tail-anchored proteins; contains an N-terminal transmembrane domain and C-terminal cytoplasmic ATPase domain

Top 10 interactors (score): PEX14 (0.918); PEX11 (0.917); PEX12 (0.914); PEX13 (0.914); PXA2 (0.912); PXA1 (0.91); SYM1 (0.906); FIS1 (0.906); HFD1 (0.9); GET3 (0.833); PEX3 (0.712); YBL039W-B (0.707); PEX15 (0.695); PEX19 (0.692); NDC1 (0.691); MGR1 (0.674); SEN1 (0.66); BNA3 (0.657); SRB8 (0.656); CDC33 (0.653)

Homologues (species, bitscore): ATAD1 (Homo sapiens, 293.9); Atad1 (Mus musculus, 293.9); atad1a (Danio rerio, 292.0); atad1 (Xenopus tropicalis, 284.6); nmd (Drosophila melanogaster, 272.3); mspn-1 (Caenorhabditis elegans, 254.2); AT4G27680 (Arabidopsis thaliana, 260.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:537811-538899:+ gene-YGR028W_AKU4011 rna-NM_001181157.3_AKU4011 cds-NP_011542.3_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000060.1:36939-38027:- gene-YGR028W_BG1 rna-NM_001181157.3_BG1 cds-NP_011542.3_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:540075-541163:+ gene-YGR028W_Bruggeman rna-NM_001181157.3_Bruggeman cds-NP_011542.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:538140-539228:+ gene-YGR028W_CAT1 rna-NM_001181157.3_CAT1 cds-NP_011542.3_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:539141-540229:+ gene-YGR028W_CBS1585 rna-NM_001181157.3_CBS1585 cds-NP_011542.3_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:533914-535002:+ gene-YGR028W_CBS436 rna-NM_001181157.3_CBS436 cds-NP_011542.3_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:531899-532987:+ gene-YGR028W_CBS6412 rna-NM_001181157.3_CBS6412 cds-NP_011542.3_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:535985-537073:+ gene-YGR028W_CBS6413 rna-NM_001181157.3_CBS6413 cds-NP_011542.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:542044-543132:+ gene-YGR028W_CENPK1137D rna-NM_001181157.3_CENPK1137D cds-NP_011542.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:526025-527113:+ gene-YGR028W_EthanolRed rna-NM_001181157.3_EthanolRed cds-NP_011542.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:529513-530601:+ gene-YGR028W_FaliES1 rna-NM_001181157.3_FaliES1 cds-NP_011542.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000020.1:68201-69289:+ gene-YGR028W_JAY291 rna-NM_001181157.3_JAY291 cds-NP_011542.3_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:536709-537797:+ gene-YGR028W_MUCL30387 rna-NM_001181157.3_MUCL30387 cds-NP_011542.3_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:539328-540416:+ gene-YGR028W_MUCL30388 rna-NM_001181157.3_MUCL30388 cds-NP_011542.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:534963-536051:+ gene-YGR028W_MUCL39482 rna-NM_001181157.3_MUCL39482 cds-NP_011542.3_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:544743-545831:+ gene-YGR028W_MUCL42920 rna-NM_001181157.3_MUCL42920 cds-NP_011542.3_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:542203-543291:+ gene-YGR028W_NCIM3186 rna-NM_001181157.3_NCIM3186 cds-NP_011542.3_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:529146-530234:+ gene-YGR028W_NCYC1407 rna-NM_001181157.3_NCYC1407 cds-NP_011542.3_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:532023-533111:+ gene-YGR028W_PE2H3 rna-NM_001181157.3_PE2H3 cds-NP_011542.3_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:537130-538218:+ gene-YGR028W_PE2H4 rna-NM_001181157.3_PE2H4 cds-NP_011542.3_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:542203-543291:+ gene-YGR028W_S288C rna-NM_001181157.3_S288C cds-NP_011542.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000021.1:18623-19711:- gene-YGR028W_SA1 rna-NM_001181157.3_SA1 cds-NP_011542.3_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:548850-549938:+ gene-YGR028W_ThermosaccDry rna-NM_001181157.3_ThermosaccDry cds-NP_011542.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:639293-640381:+ gene-YGR028W_VR1 rna-NM_001181157.3_VR1 cds-NP_011542.3_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000015.1:4331-5419:+ gene-YGR028W_ZTW1 rna-NM_001181157.3_ZTW1 cds-NP_011542.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:537400-538488:+ gene-YGR028W_Sparadoxus rna-NM_001181157.3_Sparadoxus cds-NP_011542.3_Sparadoxus 91.8 100.0 Verified 1 1 1 False True False False False

Additional files