Gene name: MSL5
Reference locus (S288C): YLR116W
Gene biotype: protein_coding
Description: Branchpoint-bridging protein; Component of commitment complex; which defines first step in splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): CEF1 (0.999); MUD2 (0.999); PRP40 (0.998); SNP1 (0.992); CDC40 (0.992); PRP39 (0.989); CBC2 (0.987); NAM8 (0.984); YHC1 (0.983); HSH155 (0.971); SMY2 (0.97); PRP42 (0.963); SNU114 (0.958); SNU56 (0.954); MUD1 (0.951); PRP5 (0.95); JIP5 (0.946); SUB2 (0.945); STO1 (0.933); NPL3 (0.933)
Homologues (species, bitscore): SF1 (Homo sapiens, 242.3); Sf1 (Mus musculus, 243.8); sf1 (Danio rerio, 223.4); sf1 (Xenopus tropicalis, 231.1); SF1 (Drosophila melanogaster, 241.5); sfa-1 (Caenorhabditis elegans, 212.6); AT5G51300 (Arabidopsis thaliana, 179.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:363305-364735:+ | gene-YLR116W_AKU4011 | rna-NM_001182003.1_AKU4011 | cds-NP_013217.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:327083-328513:+ | gene-YLR116W_BG1 | rna-NM_001182003.1_BG1 | cds-NP_013217.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:374429-375859:+ | gene-YLR116W_Bruggeman | rna-NM_001182003.1_Bruggeman | cds-NP_013217.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:374346-375776:+ | gene-YLR116W_CAT1 | rna-NM_001182003.1_CAT1 | cds-NP_013217.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:370448-371878:+ | gene-YLR116W_CBS1585 | rna-NM_001182003.1_CBS1585 | cds-NP_013217.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:360688-362118:+ | gene-YLR116W_CBS436 | rna-NM_001182003.1_CBS436 | cds-NP_013217.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:368866-370296:+ | gene-YLR116W_CBS6412 | rna-NM_001182003.1_CBS6412 | cds-NP_013217.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:370713-372143:+ | gene-YLR116W_CBS6413 | rna-NM_001182003.1_CBS6413 | cds-NP_013217.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:365844-367274:+ | gene-YLR116W_CENPK1137D | rna-NM_001182003.1_CENPK1137D | cds-NP_013217.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:363505-364935:+ | gene-YLR116W_EthanolRed | rna-NM_001182003.1_EthanolRed | cds-NP_013217.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:363016-364446:+ | gene-YLR116W_FaliES1 | rna-NM_001182003.1_FaliES1 | cds-NP_013217.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000117.1:28749-30179:- | gene-YLR116W_JAY291 | rna-NM_001182003.1_JAY291 | cds-NP_013217.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:370721-372151:+ | gene-YLR116W_MUCL30387 | rna-NM_001182003.1_MUCL30387 | cds-NP_013217.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:379503-380933:+ | gene-YLR116W_MUCL30388 | rna-NM_001182003.1_MUCL30388 | cds-NP_013217.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:370957-372387:+ | gene-YLR116W_MUCL39482 | rna-NM_001182003.1_MUCL39482 | cds-NP_013217.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:371083-372513:+ | gene-YLR116W_MUCL42920 | rna-NM_001182003.1_MUCL42920 | cds-NP_013217.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:380796-382226:+ | gene-YLR116W_NCIM3186 | rna-NM_001182003.1_NCIM3186 | cds-NP_013217.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:363230-364660:+ | gene-YLR116W_NCYC1407 | rna-NM_001182003.1_NCYC1407 | cds-NP_013217.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:368793-370223:+ | gene-YLR116W_PE2H3 | rna-NM_001182003.1_PE2H3 | cds-NP_013217.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:368534-369964:+ | gene-YLR116W_PE2H4 | rna-NM_001182003.1_PE2H4 | cds-NP_013217.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:380822-382252:+ | gene-YLR116W_S288C | rna-NM_001182003.1_S288C | cds-NP_013217.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:6697-8127:+ | gene-YLR116W_SA1 | rna-NM_001182003.1_SA1 | cds-NP_013217.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:364226-365656:+ | gene-YLR116W_ThermosaccDry | rna-NM_001182003.1_ThermosaccDry | cds-NP_013217.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:376688-378118:+ | gene-YLR116W_VR1 | rna-NM_001182003.1_VR1 | cds-NP_013217.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:362023-363453:+ | gene-YLR116W_ZTW1 | rna-NM_001182003.1_ZTW1 | cds-NP_013217.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:371858-373288:+ | gene-YLR116W_Sparadoxus | rna-NM_001182003.1_Sparadoxus | cds-NP_013217.1_Sparadoxus | 88.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |