MSK1 (YNL073W)


Gene profile

Gene name: MSK1
Reference locus (S288C): YNL073W
Gene biotype: protein_coding

Description: Lysine--tRNA ligase, mitochondrial; Mitochondrial lysine-tRNA synthetase; required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria and for aminoacylation of mitochondrially encoded tRNA(Lys)

Top 10 interactors (score): GUS1 (0.99); GLN4 (0.988); HTS1 (0.985); YHR020W (0.979); CDC60 (0.974); MES1 (0.967); ILS1 (0.961); WRS1 (0.961); TYS1 (0.959); MSW1 (0.956); MSY1 (0.942); MSF1 (0.942); NAM2 (0.937); AIM10 (0.935); ALA1 (0.933); GRS1 (0.922); ARC1 (0.917); CCT5 (0.9); FRS1 (0.889); TEF4 (0.882)

Homologues (species, bitscore): KARS (Homo sapiens, 229.9); Kars (Mus musculus, 233.8); kars (Danio rerio, 229.6); kars (Xenopus tropicalis, 229.9); Aats-lys (Drosophila melanogaster, 245.4); kars-1 (Caenorhabditis elegans, 243.4); ATKRS-1 (Arabidopsis thaliana, 235.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:482054-483784:+ gene-YNL073W_AKU4011 rna-NM_001182911.1_AKU4011 cds-NP_014326.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:386075-387805:+ gene-YNL073W_BG1 rna-NM_001182911.1_BG1 cds-NP_014326.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:492782-494512:+ gene-YNL073W_Bruggeman rna-NM_001182911.1_Bruggeman cds-NP_014326.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:535782-537512:+ gene-YNL073W_CAT1 rna-NM_001182911.1_CAT1 cds-NP_014326.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:482722-484452:+ gene-YNL073W_CBS1585 rna-NM_001182911.1_CBS1585 cds-NP_014326.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:551139-552869:+ gene-YNL073W_CBS436 rna-NM_001182911.1_CBS436 cds-NP_014326.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:477816-479546:+ gene-YNL073W_CBS6412 rna-NM_001182911.1_CBS6412 cds-NP_014326.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:479132-480862:+ gene-YNL073W_CBS6413 rna-NM_001182911.1_CBS6413 cds-NP_014326.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:482210-483940:+ gene-YNL073W_CENPK1137D rna-NM_001182911.1_CENPK1137D cds-NP_014326.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:484875-486605:+ gene-YNL073W_EthanolRed rna-NM_001182911.1_EthanolRed cds-NP_014326.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:475400-477130:+ gene-YNL073W_FaliES1 rna-NM_001182911.1_FaliES1 cds-NP_014326.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000001.1:1837-3567:+ gene-YNL073W_JAY291 rna-NM_001182911.1_JAY291 cds-NP_014326.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:488945-490675:+ gene-YNL073W_MUCL30387 rna-NM_001182911.1_MUCL30387 cds-NP_014326.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:524344-526074:+ gene-YNL073W_MUCL30388 rna-NM_001182911.1_MUCL30388 cds-NP_014326.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:480125-481855:+ gene-YNL073W_MUCL39482 rna-NM_001182911.1_MUCL39482 cds-NP_014326.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:484054-485784:+ gene-YNL073W_MUCL42920 rna-NM_001182911.1_MUCL42920 cds-NP_014326.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:488355-490085:+ gene-YNL073W_NCIM3186 rna-NM_001182911.1_NCIM3186 cds-NP_014326.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:482176-483906:+ gene-YNL073W_NCYC1407 rna-NM_001182911.1_NCYC1407 cds-NP_014326.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:485414-487144:+ gene-YNL073W_PE2H3 rna-NM_001182911.1_PE2H3 cds-NP_014326.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:480489-482219:+ gene-YNL073W_PE2H4 rna-NM_001182911.1_PE2H4 cds-NP_014326.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:488386-490116:+ gene-YNL073W_S288C rna-NM_001182911.1_S288C cds-NP_014326.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:73341-75071:+ gene-YNL073W_SA1 rna-NM_001182911.1_SA1 cds-NP_014326.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:476275-478005:+ gene-YNL073W_ThermosaccDry rna-NM_001182911.1_ThermosaccDry cds-NP_014326.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:495393-497123:+ gene-YNL073W_VR1 rna-NM_001182911.1_VR1 cds-NP_014326.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:385626-387356:+ gene-YNL073W_ZTW1 rna-NM_001182911.1_ZTW1 cds-NP_014326.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:491836-493563:+ gene-YNL073W_Sparadoxus rna-NM_001182911.1_Sparadoxus cds-NP_014326.1_Sparadoxus 86.4 99.7 Verified 1 1 1 False True False False False

Additional files