Gene name: MSI1
Reference locus (S288C): YBR195C
Gene biotype: protein_coding
Description: Subunit of chromatin assembly factor I (CAF-1); chromatin assembly by CAF-1 affects multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure; deactivation of DNA damage checkpoint after DNA repair; chromatin dynamics during transcription; and repression of divergent noncoding transcription; Msi1p localizes to nucleus and cytoplasm and independently regulates the RAS/cAMP pathway via sequestration of Npr1p kinase
Top 10 interactors (score): CAC2 (0.999); RLF2 (0.999); ASF1 (0.988); EAF3 (0.982); HIR2 (0.975); SIN3 (0.973); BAS1 (0.97); HHF1 (0.963); POL30 (0.963); RTT106 (0.961); POB3 (0.959); HHT1 (0.952); HIF1 (0.951); RPD3 (0.943); HAT1 (0.941); HIR1 (0.941); HOS1 (0.923); HHT2 (0.922); HOS2 (0.919); BUB3 (0.903)
Homologues (species, bitscore): RBBP4 (Homo sapiens, 181.8); Rbbp4 (Mus musculus, 181.8); rbb4 (Danio rerio, 182.2); rbbp4 (Xenopus tropicalis, 179.9); Caf1 (Drosophila melanogaster, 175.3); lin-53 (Caenorhabditis elegans, 174.1); MSI2 (Arabidopsis thaliana, 162.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:593984-595252:- | gene-YBR195C_AKU4011 | rna-NM_001178543.1_AKU4011 | cds-NP_009754.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:583987-585255:- | gene-YBR195C_BG1 | rna-NM_001178543.1_BG1 | cds-NP_009754.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:399842-401110:- | gene-YBR195C_Bruggeman | rna-NM_001178543.1_Bruggeman | cds-NP_009754.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:599248-600516:- | gene-YBR195C_CAT1 | rna-NM_001178543.1_CAT1 | cds-NP_009754.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:585765-587033:- | gene-YBR195C_CBS1585 | rna-NM_001178543.1_CBS1585 | cds-NP_009754.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:593313-594581:- | gene-YBR195C_CBS436 | rna-NM_001178543.1_CBS436 | cds-NP_009754.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:682374-683642:- | gene-YBR195C_CBS6412 | rna-NM_001178543.1_CBS6412 | cds-NP_009754.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:591571-592839:- | gene-YBR195C_CBS6413 | rna-NM_001178543.1_CBS6413 | cds-NP_009754.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:604388-605656:- | gene-YBR195C_CENPK1137D | rna-NM_001178543.1_CENPK1137D | cds-NP_009754.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:719140-720408:- | gene-YBR195C_EthanolRed | rna-NM_001178543.1_EthanolRed | cds-NP_009754.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:610051-611319:- | gene-YBR195C_FaliES1 | rna-NM_001178543.1_FaliES1 | cds-NP_009754.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000023.1:3655-4923:- | gene-YBR195C_JAY291 | rna-NM_001178543.1_JAY291 | cds-NP_009754.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:598521-599789:- | gene-YBR195C_MUCL30387 | rna-NM_001178543.1_MUCL30387 | cds-NP_009754.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:615598-616866:- | gene-YBR195C_MUCL30388 | rna-NM_001178543.1_MUCL30388 | cds-NP_009754.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:584138-585406:- | gene-YBR195C_MUCL39482 | rna-NM_001178543.1_MUCL39482 | cds-NP_009754.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:593559-594827:- | gene-YBR195C_MUCL42920 | rna-NM_001178543.1_MUCL42920 | cds-NP_009754.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:610411-611679:- | gene-YBR195C_NCIM3186 | rna-NM_001178543.1_NCIM3186 | cds-NP_009754.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:586246-587514:- | gene-YBR195C_NCYC1407 | rna-NM_001178543.1_NCYC1407 | cds-NP_009754.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:598859-600127:- | gene-YBR195C_PE2H3 | rna-NM_001178543.1_PE2H3 | cds-NP_009754.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:596535-597803:- | gene-YBR195C_PE2H4 | rna-NM_001178543.1_PE2H4 | cds-NP_009754.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:610614-611882:- | gene-YBR195C_S288C | rna-NM_001178543.1_S288C | cds-NP_009754.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000080.1:18309-19577:- | gene-YBR195C_SA1 | rna-NM_001178543.1_SA1 | cds-NP_009754.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:609061-610329:- | gene-YBR195C_ThermosaccDry | rna-NM_001178543.1_ThermosaccDry | cds-NP_009754.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:590234-591502:- | gene-YBR195C_VR1 | rna-NM_001178543.1_VR1 | cds-NP_009754.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:583677-584945:- | gene-YBR195C_ZTW1 | rna-NM_001178543.1_ZTW1 | cds-NP_009754.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:625585-626853:- | gene-YBR195C_Sparadoxus | rna-NM_001178543.1_Sparadoxus | cds-NP_009754.1_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |