Gene name: MSH6
Reference locus (S288C): YDR097C
Gene biotype: protein_coding
Description: Protein required for mismatch repair in mitosis and meiosis; forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; also involved in interstrand cross-link repair; potentially phosphorylated by Cdc28p
Top 10 interactors (score): RAD27 (0.999); PMS1 (0.999); MSH2 (0.999); POL3 (0.999); POL30 (0.999); MLH1 (0.999); RAD1 (0.998); POL2 (0.998); MLH3 (0.998); MSH3 (0.994); EXO1 (0.992); SGS1 (0.992); POL1 (0.988); RAD10 (0.987); RFA1 (0.986); SMC3 (0.985); OGG1 (0.98); RAD52 (0.979); CDC9 (0.977); MUS81 (0.975)
Homologues (species, bitscore): MSH6 (Homo sapiens, 530.0); Msh6 (Mus musculus, 535.8); msh6 (Danio rerio, 544.3); msh6 (Xenopus tropicalis, 536.2); Msh6 (Drosophila melanogaster, 415.6); msh-6 (Caenorhabditis elegans, 443.4); MSH6 (Arabidopsis thaliana, 505.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:617664-621392:- | gene-YDR097C_AKU4011 | rna-NM_001180405.3_AKU4011 | cds-NP_010382.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:503885-507613:+ | gene-YDR097C_BG1 | rna-NM_001180405.3_BG1 | cds-NP_010382.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:649755-653483:- | gene-YDR097C_Bruggeman | rna-NM_001180405.3_Bruggeman | cds-NP_010382.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:634559-638287:- | gene-YDR097C_CAT1 | rna-NM_001180405.3_CAT1 | cds-NP_010382.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:608684-612412:- | gene-YDR097C_CBS1585 | rna-NM_001180405.3_CBS1585 | cds-NP_010382.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:633564-637292:- | gene-YDR097C_CBS436 | rna-NM_001180405.3_CBS436 | cds-NP_010382.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:605098-608826:- | gene-YDR097C_CBS6412 | rna-NM_001180405.3_CBS6412 | cds-NP_010382.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:633629-637357:- | gene-YDR097C_CBS6413 | rna-NM_001180405.3_CBS6413 | cds-NP_010382.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:639115-642843:- | gene-YDR097C_CENPK1137D | rna-NM_001180405.3_CENPK1137D | cds-NP_010382.3_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:619453-623180:- | gene-YDR097C_EthanolRed | rna-NM_001180405.3_EthanolRed | cds-NP_010382.3_EthanolRed | 99.1 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:626246-629974:- | gene-YDR097C_FaliES1 | rna-NM_001180405.3_FaliES1 | cds-NP_010382.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000358.1:1429-5157:+ | gene-YDR097C_JAY291 | rna-NM_001180405.3_JAY291 | cds-NP_010382.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:634374-638649:- | gene-YDR097C_MUCL30387 | rna-NM_001180405.3_MUCL30387 | cds-NP_010382.3_MUCL30387 | 86.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:624684-628412:- | gene-YDR097C_MUCL30388 | rna-NM_001180405.3_MUCL30388 | cds-NP_010382.3_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:610054-613782:- | gene-YDR097C_MUCL39482 | rna-NM_001180405.3_MUCL39482 | cds-NP_010382.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:541731-545459:- | gene-YDR097C_MUCL42920 | rna-NM_001180405.3_MUCL42920 | cds-NP_010382.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:640032-643760:- | gene-YDR097C_NCIM3186 | rna-NM_001180405.3_NCIM3186 | cds-NP_010382.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:608963-612691:- | gene-YDR097C_NCYC1407 | rna-NM_001180405.3_NCYC1407 | cds-NP_010382.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:628430-632158:- | gene-YDR097C_PE2H3 | rna-NM_001180405.3_PE2H3 | cds-NP_010382.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:627735-631463:- | gene-YDR097C_PE2H4 | rna-NM_001180405.3_PE2H4 | cds-NP_010382.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:640109-643837:- | gene-YDR097C_S288C | rna-NM_001180405.3_S288C | cds-NP_010382.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:1501-5229:+ | gene-YDR097C_SA1 | rna-NM_001180405.3_SA1 | cds-NP_010382.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:625776-629503:- | gene-YDR097C_ThermosaccDry | rna-NM_001180405.3_ThermosaccDry | cds-NP_010382.3_ThermosaccDry | 99.1 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:638328-642056:- | gene-YDR097C_VR1 | rna-NM_001180405.3_VR1 | cds-NP_010382.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:623358-627086:- | gene-YDR097C_ZTW1 | rna-NM_001180405.3_ZTW1 | cds-NP_010382.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:627922-631653:- | gene-YDR097C_Sparadoxus | rna-NM_001180405.3_Sparadoxus | cds-NP_010382.3_Sparadoxus | 89.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |