Gene name: MSH5
Reference locus (S288C): YDL154W
Gene biotype: protein_coding
Description: Protein of the MutS family; forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans
Top 10 interactors (score): MLH1 (0.996); MLH3 (0.995); MND1 (0.991); SPO11 (0.99); MSH4 (0.99); MUS81 (0.984); HFM1 (0.98); MLH2 (0.961); RAD51 (0.958); SPO22 (0.955); PCH2 (0.954); PMS1 (0.943); CST9 (0.941); SGS1 (0.935); TOP3 (0.929); DMC1 (0.922); SPO16 (0.919); EXO1 (0.914); ZIP1 (0.885); HOP1 (0.867)
Homologues (species, bitscore): MSH5 (Homo sapiens, 254.2); Msh5 (Mus musculus, 245.7); MSH5 (Danio rerio, 222.6); msh5 (Xenopus tropicalis, 260.0); spel1 (Drosophila melanogaster, 168.3); msh-5 (Caenorhabditis elegans, 218.8); MSH5 (Arabidopsis thaliana, 236.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:162752-165457:+ | gene-YDL154W_AKU4011 | rna-NM_001180214.1_AKU4011 | cds-NP_010127.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:384321-387026:- | gene-YDL154W_BG1 | rna-NM_001180214.1_BG1 | cds-NP_010127.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:178800-181505:+ | gene-YDL154W_Bruggeman | rna-NM_001180214.1_Bruggeman | cds-NP_010127.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:177119-179824:+ | gene-YDL154W_CAT1 | rna-NM_001180214.1_CAT1 | cds-NP_010127.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:160783-163488:+ | gene-YDL154W_CBS1585 | rna-NM_001180214.1_CBS1585 | cds-NP_010127.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:177725-180430:+ | gene-YDL154W_CBS436 | rna-NM_001180214.1_CBS436 | cds-NP_010127.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:160036-162741:+ | gene-YDL154W_CBS6412 | rna-NM_001180214.1_CBS6412 | cds-NP_010127.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:179221-181926:+ | gene-YDL154W_CBS6413 | rna-NM_001180214.1_CBS6413 | cds-NP_010127.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:176986-179691:+ | gene-YDL154W_CENPK1137D | rna-NM_001180214.1_CENPK1137D | cds-NP_010127.1_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:173991-176696:+ | gene-YDL154W_EthanolRed | rna-NM_001180214.1_EthanolRed | cds-NP_010127.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:179523-182228:+ | gene-YDL154W_FaliES1 | rna-NM_001180214.1_FaliES1 | cds-NP_010127.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:37321-40026:- | gene-YDL154W_JAY291 | rna-NM_001180214.1_JAY291 | cds-NP_010127.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:177914-180619:+ | gene-YDL154W_MUCL30387 | rna-NM_001180214.1_MUCL30387 | cds-NP_010127.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:168775-171480:+ | gene-YDL154W_MUCL30388 | rna-NM_001180214.1_MUCL30388 | cds-NP_010127.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:161938-164643:+ | gene-YDL154W_MUCL39482 | rna-NM_001180214.1_MUCL39482 | cds-NP_010127.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:4747-7452:- | gene-YDL154W_MUCL42920 | rna-NM_001180214.1_MUCL42920 | cds-NP_010127.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:178257-180962:+ | gene-YDL154W_NCIM3186 | rna-NM_001180214.1_NCIM3186 | cds-NP_010127.1_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:161871-164576:+ | gene-YDL154W_NCYC1407 | rna-NM_001180214.1_NCYC1407 | cds-NP_010127.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:169112-171817:+ | gene-YDL154W_PE2H3 | rna-NM_001180214.1_PE2H3 | cds-NP_010127.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:169116-171821:+ | gene-YDL154W_PE2H4 | rna-NM_001180214.1_PE2H4 | cds-NP_010127.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:178334-181039:+ | gene-YDL154W_S288C | rna-NM_001180214.1_S288C | cds-NP_010127.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:43896-46601:+ | gene-YDL154W_SA1 | rna-NM_001180214.1_SA1 | cds-NP_010127.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:179284-181989:+ | gene-YDL154W_ThermosaccDry | rna-NM_001180214.1_ThermosaccDry | cds-NP_010127.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:179882-182587:+ | gene-YDL154W_VR1 | rna-NM_001180214.1_VR1 | cds-NP_010127.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:177411-180116:+ | gene-YDL154W_ZTW1 | rna-NM_001180214.1_ZTW1 | cds-NP_010127.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:179552-182263:+ | gene-YDL154W_Sparadoxus | rna-NM_001180214.1_Sparadoxus | cds-NP_010127.1_Sparadoxus | 86.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |