Gene name: MSH4
Reference locus (S288C): YFL003C
Gene biotype: protein_coding
Description: MutS protein homolog 4; Protein involved in meiotic recombination; required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein; Belongs to the DNA mismatch repair MutS family
Top 10 interactors (score): MLH1 (0.996); SPO11 (0.996); HFM1 (0.993); MLH3 (0.993); MUS81 (0.992); MND1 (0.991); MSH5 (0.99); SPO22 (0.989); PCH2 (0.977); CST9 (0.977); EXO1 (0.974); DMC1 (0.972); MLH2 (0.969); SGS1 (0.956); RAD51 (0.955); SPO16 (0.954); TOP3 (0.946); PMS1 (0.94); ZIP1 (0.901); HOP1 (0.883)
Homologues (species, bitscore): MSH4 (Homo sapiens, 332.4); Msh4 (Mus musculus, 338.6); msh4 (Danio rerio, 329.7); msh4 (Xenopus tropicalis, 318.5); spel1 (Drosophila melanogaster, 120.9); him-14 (Caenorhabditis elegans, 228.0); MSH4 (Arabidopsis thaliana, 263.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:130931-133567:- | gene-YFL003C_AKU4011 | rna-NM_001179963.1_AKU4011 | cds-NP_116652.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000079.1:16656-19292:- | gene-YFL003C_BG1 | rna-NM_001179963.1_BG1 | cds-NP_116652.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:130498-133134:- | gene-YFL003C_Bruggeman | rna-NM_001179963.1_Bruggeman | cds-NP_116652.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:136485-139121:- | gene-YFL003C_CAT1 | rna-NM_001179963.1_CAT1 | cds-NP_116652.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:131756-134392:- | gene-YFL003C_CBS1585 | rna-NM_001179963.1_CBS1585 | cds-NP_116652.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:106428-109064:- | gene-YFL003C_CBS436 | rna-NM_001179963.1_CBS436 | cds-NP_116652.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:131497-134133:- | gene-YFL003C_CBS6412 | rna-NM_001179963.1_CBS6412 | cds-NP_116652.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:134007-136643:- | gene-YFL003C_CBS6413 | rna-NM_001179963.1_CBS6413 | cds-NP_116652.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:130806-133442:- | gene-YFL003C_CENPK1137D | rna-NM_001179963.1_CENPK1137D | cds-NP_116652.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:129917-132553:- | gene-YFL003C_EthanolRed | rna-NM_001179963.1_EthanolRed | cds-NP_116652.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:131564-134200:- | gene-YFL003C_FaliES1 | rna-NM_001179963.1_FaliES1 | cds-NP_116652.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000450.1:16571-19207:- | gene-YFL003C_JAY291 | rna-NM_001179963.1_JAY291 | cds-NP_116652.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:132128-134764:- | gene-YFL003C_MUCL30387 | rna-NM_001179963.1_MUCL30387 | cds-NP_116652.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:130101-132737:- | gene-YFL003C_MUCL30388 | rna-NM_001179963.1_MUCL30388 | cds-NP_116652.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:130200-132836:- | gene-YFL003C_MUCL39482 | rna-NM_001179963.1_MUCL39482 | cds-NP_116652.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:129464-132100:- | gene-YFL003C_MUCL42920 | rna-NM_001179963.1_MUCL42920 | cds-NP_116652.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:134520-137156:- | gene-YFL003C_NCIM3186 | rna-NM_001179963.1_NCIM3186 | cds-NP_116652.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:131215-133851:- | gene-YFL003C_NCYC1407 | rna-NM_001179963.1_NCYC1407 | cds-NP_116652.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:151105-153741:- | gene-YFL003C_PE2H3 | rna-NM_001179963.1_PE2H3 | cds-NP_116652.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:150653-153289:- | gene-YFL003C_PE2H4 | rna-NM_001179963.1_PE2H4 | cds-NP_116652.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:134521-137157:- | gene-YFL003C_S288C | rna-NM_001179963.1_S288C | cds-NP_116652.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:180280-182916:+ | gene-YFL003C_SA1 | rna-NM_001179963.1_SA1 | cds-NP_116652.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:130724-133360:- | gene-YFL003C_ThermosaccDry | rna-NM_001179963.1_ThermosaccDry | cds-NP_116652.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:140615-143251:- | gene-YFL003C_VR1 | rna-NM_001179963.1_VR1 | cds-NP_116652.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:61173-63809:- | gene-YFL003C_ZTW1 | rna-NM_001179963.1_ZTW1 | cds-NP_116652.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:155263-157899:- | gene-YFL003C_Sparadoxus | rna-NM_001179963.1_Sparadoxus | cds-NP_116652.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |