MSH3 (YCR092C)


Gene profile

Gene name: MSH3
Reference locus (S288C): YCR092C
Gene biotype: protein_coding

Description: Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability; Belongs to the DNA mismatch repair MutS family. MSH3 subfamily

Top 10 interactors (score): MLH1 (0.999); PMS1 (0.999); MSH2 (0.999); MLH3 (0.997); MSH6 (0.994); RAD10 (0.989); EXO1 (0.985); RAD1 (0.981); POL30 (0.981); RAD14 (0.965); RAD27 (0.965); RAD52 (0.962); SLX1 (0.959); RAD2 (0.955); POL2 (0.953); OGG1 (0.949); MUS81 (0.948); POL3 (0.947); MLH2 (0.936); RAD51 (0.921)

Homologues (species, bitscore): MSH3 (Homo sapiens, 453.8); Msh3 (Mus musculus, 448.7); msh3 (Danio rerio, 415.2); msh3 (Xenopus tropicalis, 441.4); Msh6 (Drosophila melanogaster, 214.9); msh-6 (Caenorhabditis elegans, 235.7); MSH3 (Arabidopsis thaliana, 388.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:271704-274760:- gene-YCR092C_AKU4011 rna-NM_001178798.1_AKU4011 cds-NP_010016.2_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000067.1:130006-133062:- gene-YCR092C_BG1 rna-NM_001178798.1_BG1 cds-NP_010016.2_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:268516-271572:- gene-YCR092C_Bruggeman rna-NM_001178798.1_Bruggeman cds-NP_010016.2_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:278511-281567:- gene-YCR092C_CAT1 rna-NM_001178798.1_CAT1 cds-NP_010016.2_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:266451-269507:- gene-YCR092C_CBS1585 rna-NM_001178798.1_CBS1585 cds-NP_010016.2_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:277843-280899:- gene-YCR092C_CBS436 rna-NM_001178798.1_CBS436 cds-NP_010016.2_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:257598-260654:- gene-YCR092C_CBS6412 rna-NM_001178798.1_CBS6412 cds-NP_010016.2_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:272150-275206:- gene-YCR092C_CBS6413 rna-NM_001178798.1_CBS6413 cds-NP_010016.2_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:275992-279048:- gene-YCR092C_CENPK1137D rna-NM_001178798.1_CENPK1137D cds-NP_010016.2_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:267349-270405:- gene-YCR092C_EthanolRed rna-NM_001178798.1_EthanolRed cds-NP_010016.2_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:273449-276505:- gene-YCR092C_FaliES1 rna-NM_001178798.1_FaliES1 cds-NP_010016.2_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000323.1:13306-16362:+ gene-YCR092C_JAY291 rna-NM_001178798.1_JAY291 cds-NP_010016.2_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:265317-268373:- gene-YCR092C_MUCL30387 rna-NM_001178798.1_MUCL30387 cds-NP_010016.2_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:264138-267194:- gene-YCR092C_MUCL30388 rna-NM_001178798.1_MUCL30388 cds-NP_010016.2_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:273095-276151:- gene-YCR092C_MUCL39482 rna-NM_001178798.1_MUCL39482 cds-NP_010016.2_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:269306-272362:- gene-YCR092C_MUCL42920 rna-NM_001178798.1_MUCL42920 cds-NP_010016.2_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:276396-279452:- gene-YCR092C_NCIM3186 rna-NM_001178798.1_NCIM3186 cds-NP_010016.2_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:273738-276794:- gene-YCR092C_NCYC1407 rna-NM_001178798.1_NCYC1407 cds-NP_010016.2_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:288024-291080:- gene-YCR092C_PE2H3 rna-NM_001178798.1_PE2H3 cds-NP_010016.2_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:276576-279632:- gene-YCR092C_PE2H4 rna-NM_001178798.1_PE2H4 cds-NP_010016.2_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:276764-279820:- gene-YCR092C_S288C rna-NM_001178798.1_S288C cds-NP_010016.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000044.1:76752-79808:- gene-YCR092C_SA1 rna-NM_001178798.1_SA1 cds-NP_010016.2_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:273403-276459:- gene-YCR092C_ThermosaccDry rna-NM_001178798.1_ThermosaccDry cds-NP_010016.2_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:283564-286620:- gene-YCR092C_VR1 rna-NM_001178798.1_VR1 cds-NP_010016.2_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:270107-273163:- gene-YCR092C_ZTW1 rna-NM_001178798.1_ZTW1 cds-NP_010016.2_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:304480-307533:- gene-YCR092C_Sparadoxus rna-NM_001178798.1_Sparadoxus cds-NP_010016.2_Sparadoxus 87.9 99.9 Verified 1 1 1 False True False False False

Additional files