Gene name: MSG5
Reference locus (S288C): YNL053W
Gene biotype: protein_coding
Description: Tyrosine-protein phosphatase MSG5; Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p; MSG5 has a paralog, SDP1, that arose from the whole genome duplication; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily
Top 10 interactors (score): FUS3 (0.999); SLT2 (0.998); KSS1 (0.995); KDX1 (0.92); PTP2 (0.913); MKK1 (0.869); STE5 (0.862); PTP3 (0.853); PTC1 (0.835); HOG1 (0.82); BCK1 (0.8); STE7 (0.793); SST2 (0.772); CMP2 (0.761); CNA1 (0.758); GPA1 (0.753); PTP1 (0.742); HEK2 (0.72); STE20 (0.718); STE11 (0.715)
Homologues (species, bitscore): DUSP10 (Homo sapiens, 77.4); Ssh1 (Mus musculus, 77.4); si:dkey-175m17.7 (Danio rerio, 79.0); dusp10.2 (Xenopus tropicalis, 73.9); puc (Drosophila melanogaster, 72.4); vhp-1 (Caenorhabditis elegans, 71.6); MKP1 (Arabidopsis thaliana, 61.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:517742-519211:+ | gene-YNL053W_AKU4011 | rna-NM_001182892.3_AKU4011 | cds-NP_014345.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:421702-423171:+ | gene-YNL053W_BG1 | rna-NM_001182892.3_BG1 | cds-NP_014345.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:534853-536322:+ | gene-YNL053W_Bruggeman | rna-NM_001182892.3_Bruggeman | cds-NP_014345.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:571414-572883:+ | gene-YNL053W_CAT1 | rna-NM_001182892.3_CAT1 | cds-NP_014345.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:518412-519881:+ | gene-YNL053W_CBS1585 | rna-NM_001182892.3_CBS1585 | cds-NP_014345.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:586662-588131:+ | gene-YNL053W_CBS436 | rna-NM_001182892.3_CBS436 | cds-NP_014345.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:513505-514974:+ | gene-YNL053W_CBS6412 | rna-NM_001182892.3_CBS6412 | cds-NP_014345.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:514823-516292:+ | gene-YNL053W_CBS6413 | rna-NM_001182892.3_CBS6413 | cds-NP_014345.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:523528-524997:+ | gene-YNL053W_CENPK1137D | rna-NM_001182892.3_CENPK1137D | cds-NP_014345.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:520564-522033:+ | gene-YNL053W_EthanolRed | rna-NM_001182892.3_EthanolRed | cds-NP_014345.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:511089-512558:+ | gene-YNL053W_FaliES1 | rna-NM_001182892.3_FaliES1 | cds-NP_014345.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000040.1:26133-27602:+ | gene-YNL053W_JAY291 | rna-NM_001182892.3_JAY291 | cds-NP_014345.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:531187-532656:+ | gene-YNL053W_MUCL30387 | rna-NM_001182892.3_MUCL30387 | cds-NP_014345.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:560607-562076:+ | gene-YNL053W_MUCL30388 | rna-NM_001182892.3_MUCL30388 | cds-NP_014345.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:515828-517297:+ | gene-YNL053W_MUCL39482 | rna-NM_001182892.3_MUCL39482 | cds-NP_014345.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:519900-521369:+ | gene-YNL053W_MUCL42920 | rna-NM_001182892.3_MUCL42920 | cds-NP_014345.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:529911-531380:+ | gene-YNL053W_NCIM3186 | rna-NM_001182892.3_NCIM3186 | cds-NP_014345.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:517880-519349:+ | gene-YNL053W_NCYC1407 | rna-NM_001182892.3_NCYC1407 | cds-NP_014345.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:521049-522518:+ | gene-YNL053W_PE2H3 | rna-NM_001182892.3_PE2H3 | cds-NP_014345.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:516124-517593:+ | gene-YNL053W_PE2H4 | rna-NM_001182892.3_PE2H4 | cds-NP_014345.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:529942-531411:+ | gene-YNL053W_S288C | rna-NM_001182892.3_S288C | cds-NP_014345.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000024.1:108973-110442:+ | gene-YNL053W_SA1 | rna-NM_001182892.3_SA1 | cds-NP_014345.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:511964-513433:+ | gene-YNL053W_ThermosaccDry | rna-NM_001182892.3_ThermosaccDry | cds-NP_014345.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:531010-532479:+ | gene-YNL053W_VR1 | rna-NM_001182892.3_VR1 | cds-NP_014345.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:421284-422753:+ | gene-YNL053W_ZTW1 | rna-NM_001182892.3_ZTW1 | cds-NP_014345.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:527249-528721:+ | gene-YNL053W_Sparadoxus | rna-NM_001182892.3_Sparadoxus | cds-NP_014345.3_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |