Gene name: MSC2
Reference locus (S288C): YDR205W
Gene biotype: protein_coding
Description: Solute carrier family 30 (zinc transporter), member 5/7; Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Zrg17p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; localizes to ER and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids
Top 10 interactors (score): ZRG17 (0.999); YKE4 (0.988); ZRT3 (0.962); ATX2 (0.923); ZRT1 (0.92); ZRT2 (0.902); MMT1 (0.869); ZAP1 (0.784); FET4 (0.759); MMT2 (0.738); MCD4 (0.708); APE3 (0.691); TFA1 (0.664); DPH5 (0.65); APM1 (0.649); CUP1-1 (0.589); STE11 (0.581); CUP1-2 (0.581); ATC1 (0.571); CDC14 (0.569)
Homologues (species, bitscore): SLC30A5 (Homo sapiens, 193.4); Slc30a5 (Mus musculus, 198.7); slc30a5 (Danio rerio, 201.1); slc30a5 (Xenopus tropicalis, 199.9); ZnT86D (Drosophila melanogaster, 180.6); Y105E8A.3 (Caenorhabditis elegans, 189.9); AT2G04620 (Arabidopsis thaliana, 157.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:827874-830048:+ | gene-YDR205W_AKU4011 | rna-NM_001180513.3_AKU4011 | cds-NP_010491.4_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:295766-297940:- | gene-YDR205W_BG1 | rna-NM_001180513.3_BG1 | cds-NP_010491.4_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:860287-862461:+ | gene-YDR205W_Bruggeman | rna-NM_001180513.3_Bruggeman | cds-NP_010491.4_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:847559-849733:+ | gene-YDR205W_CAT1 | rna-NM_001180513.3_CAT1 | cds-NP_010491.4_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:818234-820408:+ | gene-YDR205W_CBS1585 | rna-NM_001180513.3_CBS1585 | cds-NP_010491.4_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:847243-849417:+ | gene-YDR205W_CBS436 | rna-NM_001180513.3_CBS436 | cds-NP_010491.4_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:815041-817215:+ | gene-YDR205W_CBS6412 | rna-NM_001180513.3_CBS6412 | cds-NP_010491.4_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:845585-847759:+ | gene-YDR205W_CBS6413 | rna-NM_001180513.3_CBS6413 | cds-NP_010491.4_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:858178-860352:+ | gene-YDR205W_CENPK1137D | rna-NM_001180513.3_CENPK1137D | cds-NP_010491.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:828623-830797:+ | gene-YDR205W_EthanolRed | rna-NM_001180513.3_EthanolRed | cds-NP_010491.4_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:836835-839009:+ | gene-YDR205W_FaliES1 | rna-NM_001180513.3_FaliES1 | cds-NP_010491.4_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:10337-12511:- | gene-YDR205W_JAY291 | rna-NM_001180513.3_JAY291 | cds-NP_010491.4_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:845940-848114:+ | gene-YDR205W_MUCL30387 | rna-NM_001180513.3_MUCL30387 | cds-NP_010491.4_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:834189-836363:+ | gene-YDR205W_MUCL30388 | rna-NM_001180513.3_MUCL30388 | cds-NP_010491.4_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:819681-821855:+ | gene-YDR205W_MUCL39482 | rna-NM_001180513.3_MUCL39482 | cds-NP_010491.4_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:758387-760561:+ | gene-YDR205W_MUCL42920 | rna-NM_001180513.3_MUCL42920 | cds-NP_010491.4_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:859269-861443:+ | gene-YDR205W_NCIM3186 | rna-NM_001180513.3_NCIM3186 | cds-NP_010491.4_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:822815-824989:+ | gene-YDR205W_NCYC1407 | rna-NM_001180513.3_NCYC1407 | cds-NP_010491.4_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:839572-841746:+ | gene-YDR205W_PE2H3 | rna-NM_001180513.3_PE2H3 | cds-NP_010491.4_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:838871-841045:+ | gene-YDR205W_PE2H4 | rna-NM_001180513.3_PE2H4 | cds-NP_010491.4_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:859346-861520:+ | gene-YDR205W_S288C | rna-NM_001180513.3_S288C | cds-NP_010491.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:205050-207224:+ | gene-YDR205W_SA1 | rna-NM_001180513.3_SA1 | cds-NP_010491.4_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:834990-837164:+ | gene-YDR205W_ThermosaccDry | rna-NM_001180513.3_ThermosaccDry | cds-NP_010491.4_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:850219-852393:+ | gene-YDR205W_VR1 | rna-NM_001180513.3_VR1 | cds-NP_010491.4_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:97710-99884:+ | gene-YDR205W_ZTW1 | rna-NM_001180513.3_ZTW1 | cds-NP_010491.4_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:839871-842051:+ | gene-YDR205W_Sparadoxus | rna-NM_001180513.3_Sparadoxus | cds-NP_010491.4_Sparadoxus | 87.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |