MRS6 (YOR370C)


Gene profile

Gene name: MRS6
Reference locus (S288C): YOR370C
Gene biotype: protein_coding

Description: Rab proteins geranylgeranyltransferase component A; Rab escort protein; forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p); sequence similarity to mammalian choroideraemia gene; relative distribution to the nucleus increases upon DNA replication stress

Top 10 interactors (score): YPT1 (0.995); BET2 (0.995); SEC4 (0.99); BET4 (0.986); YPT6 (0.983); YPT7 (0.982); VPS21 (0.981); YPT53 (0.979); YPT52 (0.977); SFP1 (0.975); GDI1 (0.974); YPT10 (0.969); VPS9 (0.965); BET5 (0.944); TRS23 (0.944); TRS33 (0.939); TRS20 (0.939); BET3 (0.937); TRS31 (0.936); MON1 (0.925)

Homologues (species, bitscore): GDI2 (Homo sapiens, 124.0); Gdi1 (Mus musculus, 125.2); gdi2 (Danio rerio, 125.6); ENSXETP00000020569 (Xenopus tropicalis, 127.9); Gdi (Drosophila melanogaster, 131.7); rep-1 (Caenorhabditis elegans, 117.5); REP (Arabidopsis thaliana, 146.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:1015783-1017594:- gene-YOR370C_AKU4011 rna-NM_001183790.1_AKU4011 cds-NP_015015.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000078.1:52944-54755:- gene-YOR370C_BG1 rna-NM_001183790.1_BG1 cds-NP_015015.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:1000590-1002401:- gene-YOR370C_Bruggeman rna-NM_001183790.1_Bruggeman cds-NP_015015.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:1001236-1003047:- gene-YOR370C_CAT1 rna-NM_001183790.1_CAT1 cds-NP_015015.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:1000193-1002004:- gene-YOR370C_CBS1585 rna-NM_001183790.1_CBS1585 cds-NP_015015.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:994999-996810:- gene-YOR370C_CBS436 rna-NM_001183790.1_CBS436 cds-NP_015015.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:229490-231301:- gene-YOR370C_CBS6412 rna-NM_001183790.1_CBS6412 cds-NP_015015.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:1004466-1006277:- gene-YOR370C_CBS6413 rna-NM_001183790.1_CBS6413 cds-NP_015015.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:1029005-1030816:- gene-YOR370C_CENPK1137D rna-NM_001183790.1_CENPK1137D cds-NP_015015.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:244502-246313:- gene-YOR370C_EthanolRed rna-NM_001183790.1_EthanolRed cds-NP_015015.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:997331-999142:- gene-YOR370C_FaliES1 rna-NM_001183790.1_FaliES1 cds-NP_015015.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000078.1:6534-8345:+ gene-YOR370C_JAY291 rna-NM_001183790.1_JAY291 cds-NP_015015.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:1009921-1011732:- gene-YOR370C_MUCL30387 rna-NM_001183790.1_MUCL30387 cds-NP_015015.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:1017944-1019755:- gene-YOR370C_MUCL30388 rna-NM_001183790.1_MUCL30388 cds-NP_015015.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:1006728-1008539:- gene-YOR370C_MUCL39482 rna-NM_001183790.1_MUCL39482 cds-NP_015015.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:1014340-1016151:- gene-YOR370C_MUCL42920 rna-NM_001183790.1_MUCL42920 cds-NP_015015.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:1029072-1030883:- gene-YOR370C_NCIM3186 rna-NM_001183790.1_NCIM3186 cds-NP_015015.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:1007736-1009547:- gene-YOR370C_NCYC1407 rna-NM_001183790.1_NCYC1407 cds-NP_015015.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:1003003-1004814:- gene-YOR370C_PE2H3 rna-NM_001183790.1_PE2H3 cds-NP_015015.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:1019354-1021165:- gene-YOR370C_PE2H4 rna-NM_001183790.1_PE2H4 cds-NP_015015.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:1029183-1030994:- gene-YOR370C_S288C rna-NM_001183790.1_S288C cds-NP_015015.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000016.1:133717-135528:- gene-YOR370C_SA1 rna-NM_001183790.1_SA1 cds-NP_015015.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:996501-998312:- gene-YOR370C_ThermosaccDry rna-NM_001183790.1_ThermosaccDry cds-NP_015015.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:1057985-1059796:- gene-YOR370C_VR1 rna-NM_001183790.1_VR1 cds-NP_015015.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:729222-731033:- gene-YOR370C_ZTW1 rna-NM_001183790.1_ZTW1 cds-NP_015015.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:1003282-1005093:- gene-YOR370C_Sparadoxus rna-NM_001183790.1_Sparadoxus cds-NP_015015.1_Sparadoxus 91.6 100.0 Verified 1 1 1 False True False False False

Additional files