Gene name: MRS4
Reference locus (S288C): YKR052C
Gene biotype: protein_coding
Description: Mitochondrial RNA-splicing protein MRS4; Iron transporter of the mitochondrial carrier family; mediates Fe2+ transport across the inner mitochondrial membrane; active under low-iron conditions; may transport other cations; protein abundance increases in response to DNA replication stress; MRS4 has a paralog, MRS3, that arose from the whole genome duplication
Top 10 interactors (score): YFH1 (0.973); CCC1 (0.969); SMF3 (0.946); ISU1 (0.899); ISU2 (0.894); MRS2 (0.888); ATM1 (0.87); FET3 (0.857); AFT1 (0.819); FTR1 (0.793); YAH1 (0.79); CCC2 (0.782); RIM2 (0.782); GRX5 (0.768); AFT2 (0.766); MRS3 (0.731); ARN1 (0.714); TIS11 (0.713); JAC1 (0.709); ISD11 (0.706)
Homologues (species, bitscore): SLC25A37 (Homo sapiens, 229.9); Slc25a37 (Mus musculus, 224.2); slc25a37 (Danio rerio, 220.3); slc25a37 (Xenopus tropicalis, 215.3); mfrn (Drosophila melanogaster, 197.2); mfn-1 (Caenorhabditis elegans, 201.4); AT1G07030 (Arabidopsis thaliana, 189.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:517847-518761:- | gene-YKR052C_AKU4011 | rna-NM_001179842.1_AKU4011 | cds-NP_012978.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:124765-125679:+ | gene-YKR052C_BG1 | rna-NM_001179842.1_BG1 | cds-NP_012978.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:540024-540938:- | gene-YKR052C_Bruggeman | rna-NM_001179842.1_Bruggeman | cds-NP_012978.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:536448-537362:- | gene-YKR052C_CAT1 | rna-NM_001179842.1_CAT1 | cds-NP_012978.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:530587-531501:- | gene-YKR052C_CBS1585 | rna-NM_001179842.1_CBS1585 | cds-NP_012978.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:529419-530333:- | gene-YKR052C_CBS436 | rna-NM_001179842.1_CBS436 | cds-NP_012978.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:514765-515679:- | gene-YKR052C_CBS6412 | rna-NM_001179842.1_CBS6412 | cds-NP_012978.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:530407-531321:- | gene-YKR052C_CBS6413 | rna-NM_001179842.1_CBS6413 | cds-NP_012978.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:532206-533120:- | gene-YKR052C_CENPK1137D | rna-NM_001179842.1_CENPK1137D | cds-NP_012978.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:528168-529082:- | gene-YKR052C_EthanolRed | rna-NM_001179842.1_EthanolRed | cds-NP_012978.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:531305-532219:- | gene-YKR052C_FaliES1 | rna-NM_001179842.1_FaliES1 | cds-NP_012978.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:21582-22496:+ | gene-YKR052C_JAY291 | rna-NM_001179842.1_JAY291 | cds-NP_012978.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:540422-541336:- | gene-YKR052C_MUCL30387 | rna-NM_001179842.1_MUCL30387 | cds-NP_012978.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:534784-535698:- | gene-YKR052C_MUCL30388 | rna-NM_001179842.1_MUCL30388 | cds-NP_012978.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:529915-530829:- | gene-YKR052C_MUCL39482 | rna-NM_001179842.1_MUCL39482 | cds-NP_012978.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:535938-536852:- | gene-YKR052C_MUCL42920 | rna-NM_001179842.1_MUCL42920 | cds-NP_012978.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:532539-533453:- | gene-YKR052C_NCIM3186 | rna-NM_001179842.1_NCIM3186 | cds-NP_012978.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:530129-531043:- | gene-YKR052C_NCYC1407 | rna-NM_001179842.1_NCYC1407 | cds-NP_012978.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:555495-556409:- | gene-YKR052C_PE2H3 | rna-NM_001179842.1_PE2H3 | cds-NP_012978.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:539890-540804:- | gene-YKR052C_PE2H4 | rna-NM_001179842.1_PE2H4 | cds-NP_012978.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:532550-533464:- | gene-YKR052C_S288C | rna-NM_001179842.1_S288C | cds-NP_012978.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000093.1:15651-16565:- | gene-YKR052C_SA1 | rna-NM_001179842.1_SA1 | cds-NP_012978.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:530544-531458:- | gene-YKR052C_ThermosaccDry | rna-NM_001179842.1_ThermosaccDry | cds-NP_012978.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:530563-531477:- | gene-YKR052C_VR1 | rna-NM_001179842.1_VR1 | cds-NP_012978.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:528533-529447:- | gene-YKR052C_ZTW1 | rna-NM_001179842.1_ZTW1 | cds-NP_012978.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:553918-554832:- | gene-YKR052C_Sparadoxus | rna-NM_001179842.1_Sparadoxus | cds-NP_012978.1_Sparadoxus | 93.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |