Gene name: MRPL3
Reference locus (S288C): YMR024W
Gene biotype: protein_coding
Description: Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily
Top 10 interactors (score): YML6 (0.999); RSM23 (0.999); IMG1 (0.999); MRPL10 (0.998); MRPS16 (0.998); MRPL16 (0.998); MRPL23 (0.998); MRPL51 (0.998); MRPL4 (0.998); MRP7 (0.998); MRPS28 (0.997); MRPL17 (0.997); RML2 (0.997); MRPS5 (0.997); MRP20 (0.997); MRPL8 (0.997); MRP17 (0.996); MRPS9 (0.996); MRPL32 (0.996); IMG2 (0.996)
Homologues (species, bitscore): mrpl44 (Xenopus tropicalis, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:371474-372646:+ | gene-YMR024W_AKU4011 | rna-NM_001182520.1_AKU4011 | cds-NP_013737.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:170209-171381:- | gene-YMR024W_BG1 | rna-NM_001182520.1_BG1 | cds-NP_013737.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:311413-312585:+ | gene-YMR024W_Bruggeman | rna-NM_001182520.1_Bruggeman | cds-NP_013737.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:313927-315099:+ | gene-YMR024W_CAT1 | rna-NM_001182520.1_CAT1 | cds-NP_013737.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:304413-305585:+ | gene-YMR024W_CBS1585 | rna-NM_001182520.1_CBS1585 | cds-NP_013737.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:309964-311136:+ | gene-YMR024W_CBS436 | rna-NM_001182520.1_CBS436 | cds-NP_013737.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:417817-418989:+ | gene-YMR024W_CBS6412 | rna-NM_001182520.1_CBS6412 | cds-NP_013737.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:303671-304843:+ | gene-YMR024W_CBS6413 | rna-NM_001182520.1_CBS6413 | cds-NP_013737.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:316606-317778:+ | gene-YMR024W_CENPK1137D | rna-NM_001182520.1_CENPK1137D | cds-NP_013737.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:304245-305417:+ | gene-YMR024W_EthanolRed | rna-NM_001182520.1_EthanolRed | cds-NP_013737.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:307428-308600:+ | gene-YMR024W_FaliES1 | rna-NM_001182520.1_FaliES1 | cds-NP_013737.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:128340-129512:- | gene-YMR024W_JAY291 | rna-NM_001182520.1_JAY291 | cds-NP_013737.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:309375-310547:+ | gene-YMR024W_MUCL30387 | rna-NM_001182520.1_MUCL30387 | cds-NP_013737.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:313799-314971:+ | gene-YMR024W_MUCL30388 | rna-NM_001182520.1_MUCL30388 | cds-NP_013737.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:304698-305870:+ | gene-YMR024W_MUCL39482 | rna-NM_001182520.1_MUCL39482 | cds-NP_013737.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:310514-311686:+ | gene-YMR024W_MUCL42920 | rna-NM_001182520.1_MUCL42920 | cds-NP_013737.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:321829-323001:+ | gene-YMR024W_NCIM3186 | rna-NM_001182520.1_NCIM3186 | cds-NP_013737.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:304615-305787:+ | gene-YMR024W_NCYC1407 | rna-NM_001182520.1_NCYC1407 | cds-NP_013737.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:310560-311732:+ | gene-YMR024W_PE2H3 | rna-NM_001182520.1_PE2H3 | cds-NP_013737.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:316655-317827:+ | gene-YMR024W_PE2H4 | rna-NM_001182520.1_PE2H4 | cds-NP_013737.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:321875-323047:+ | gene-YMR024W_S288C | rna-NM_001182520.1_S288C | cds-NP_013737.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:215217-216389:- | gene-YMR024W_SA1 | rna-NM_001182520.1_SA1 | cds-NP_013737.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:304497-305669:+ | gene-YMR024W_ThermosaccDry | rna-NM_001182520.1_ThermosaccDry | cds-NP_013737.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:309195-310367:+ | gene-YMR024W_VR1 | rna-NM_001182520.1_VR1 | cds-NP_013737.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:283514-284686:+ | gene-YMR024W_ZTW1 | rna-NM_001182520.1_ZTW1 | cds-NP_013737.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:317453-318624:+ | gene-YMR024W_Sparadoxus | rna-NM_001182520.1_Sparadoxus | cds-NP_013737.1_Sparadoxus | 91.4 | 99.9 | Verified | 1 | 1 | 0 | False | False | True | False | False |