Gene name: MRM2
Reference locus (S288C): YGL136C
Gene biotype: protein_coding
Description: Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family
Top 10 interactors (score): MRM1 (0.981); MTG2 (0.938); MTG1 (0.883); ESF2 (0.867); PUS2 (0.86); ENP1 (0.851); TRM732 (0.84); GCD10 (0.819); TUB4 (0.812); PUS1 (0.811); NCL1 (0.785); DEG1 (0.776); EBP2 (0.722); NOP2 (0.715); YGL138C (0.712); YMR147W (0.71); PUF6 (0.706); MRH4 (0.705); RRP12 (0.699); NOP14 (0.698)
Homologues (species, bitscore): FTSJ2 (Homo sapiens, 119.0); Ftsj2 (Mus musculus, 126.3); FTSJ2 (Danio rerio, 123.6); ftsj2 (Xenopus tropicalis, 109.0); CG11447 (Drosophila melanogaster, 80.9); H06I04.3 (Caenorhabditis elegans, 77.0); AT4G25730 (Arabidopsis thaliana, 70.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:255460-256422:- | gene-YGL136C_AKU4011 | rna-NM_001181001.1_AKU4011 | cds-NP_011379.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:148505-149467:+ | gene-YGL136C_BG1 | rna-NM_001181001.1_BG1 | cds-NP_011379.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:257912-258874:- | gene-YGL136C_Bruggeman | rna-NM_001181001.1_Bruggeman | cds-NP_011379.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:253500-254462:- | gene-YGL136C_CAT1 | rna-NM_001181001.1_CAT1 | cds-NP_011379.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:258842-259804:- | gene-YGL136C_CBS1585 | rna-NM_001181001.1_CBS1585 | cds-NP_011379.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:253452-254414:- | gene-YGL136C_CBS436 | rna-NM_001181001.1_CBS436 | cds-NP_011379.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:245052-246014:- | gene-YGL136C_CBS6412 | rna-NM_001181001.1_CBS6412 | cds-NP_011379.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:253398-254360:- | gene-YGL136C_CBS6413 | rna-NM_001181001.1_CBS6413 | cds-NP_011379.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:253156-254118:- | gene-YGL136C_CENPK1137D | rna-NM_001181001.1_CENPK1137D | cds-NP_011379.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:245632-246594:- | gene-YGL136C_EthanolRed | rna-NM_001181001.1_EthanolRed | cds-NP_011379.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:246878-247840:- | gene-YGL136C_FaliES1 | rna-NM_001181001.1_FaliES1 | cds-NP_011379.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:96704-97666:- | gene-YGL136C_JAY291 | rna-NM_001181001.1_JAY291 | cds-NP_011379.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:254882-255844:- | gene-YGL136C_MUCL30387 | rna-NM_001181001.1_MUCL30387 | cds-NP_011379.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:258000-258962:- | gene-YGL136C_MUCL30388 | rna-NM_001181001.1_MUCL30388 | cds-NP_011379.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:255623-256585:- | gene-YGL136C_MUCL39482 | rna-NM_001181001.1_MUCL39482 | cds-NP_011379.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:258874-259836:- | gene-YGL136C_MUCL42920 | rna-NM_001181001.1_MUCL42920 | cds-NP_011379.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:252897-253859:- | gene-YGL136C_NCIM3186 | rna-NM_001181001.1_NCIM3186 | cds-NP_011379.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:247114-248076:- | gene-YGL136C_NCYC1407 | rna-NM_001181001.1_NCYC1407 | cds-NP_011379.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:249003-249965:- | gene-YGL136C_PE2H3 | rna-NM_001181001.1_PE2H3 | cds-NP_011379.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:254001-254963:- | gene-YGL136C_PE2H4 | rna-NM_001181001.1_PE2H4 | cds-NP_011379.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:252897-253859:- | gene-YGL136C_S288C | rna-NM_001181001.1_S288C | cds-NP_011379.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000081.1:888-1850:+ | gene-YGL136C_SA1 | rna-NM_001181001.1_SA1 | cds-NP_011379.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:247107-248069:- | gene-YGL136C_ThermosaccDry | rna-NM_001181001.1_ThermosaccDry | cds-NP_011379.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:253917-254879:- | gene-YGL136C_VR1 | rna-NM_001181001.1_VR1 | cds-NP_011379.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:245184-246146:- | gene-YGL136C_ZTW1 | rna-NM_001181001.1_ZTW1 | cds-NP_011379.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:251253-252215:- | gene-YGL136C_Sparadoxus | rna-NM_001181001.1_Sparadoxus | cds-NP_011379.1_Sparadoxus | 90.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |