Gene name: MRK1
Reference locus (S288C): YDL079C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase MRK1; Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication
Top 10 interactors (score): PGM2 (0.889); ISF1 (0.886); KSP1 (0.832); YMR206W (0.791); HRR25 (0.778); BMH2 (0.777); BMH1 (0.777); MBR1 (0.774); TEP1 (0.768); DAS2 (0.756); URK1 (0.739); FUR1 (0.739); SST2 (0.736); RGS2 (0.736); YPK1 (0.693); KOG1 (0.686); GAC1 (0.686); ESS1 (0.68); HSC82 (0.68); HSP82 (0.68)
Homologues (species, bitscore): GSK3A (Homo sapiens, 342.8); Gsk3b (Mus musculus, 347.1); gsk3b (Danio rerio, 346.3); gsk3b (Xenopus tropicalis, 350.1); sgg (Drosophila melanogaster, 338.2); gsk-3 (Caenorhabditis elegans, 345.1); F2P16.21 (Arabidopsis thaliana, 357.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:297567-299362:- | gene-YDL079C_AKU4011 | rna-NM_001180138.1_AKU4011 | cds-NP_010204.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:250585-252382:+ | gene-YDL079C_BG1 | rna-NM_001180138.1_BG1 | cds-NP_010204.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:315234-317030:- | gene-YDL079C_Bruggeman | rna-NM_001180138.1_Bruggeman | cds-NP_010204.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:311724-313521:- | gene-YDL079C_CAT1 | rna-NM_001180138.1_CAT1 | cds-NP_010204.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:295839-297634:- | gene-YDL079C_CBS1585 | rna-NM_001180138.1_CBS1585 | cds-NP_010204.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:312502-314299:- | gene-YDL079C_CBS436 | rna-NM_001180138.1_CBS436 | cds-NP_010204.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:294266-296061:- | gene-YDL079C_CBS6412 | rna-NM_001180138.1_CBS6412 | cds-NP_010204.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:313892-315687:- | gene-YDL079C_CBS6413 | rna-NM_001180138.1_CBS6413 | cds-NP_010204.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:311774-313571:- | gene-YDL079C_CENPK1137D | rna-NM_001180138.1_CENPK1137D | cds-NP_010204.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:308601-310398:- | gene-YDL079C_EthanolRed | rna-NM_001180138.1_EthanolRed | cds-NP_010204.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:314573-316370:- | gene-YDL079C_FaliES1 | rna-NM_001180138.1_FaliES1 | cds-NP_010204.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:84624-86421:- | gene-YDL079C_JAY291 | rna-NM_001180138.1_JAY291 | cds-NP_010204.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:312749-314546:- | gene-YDL079C_MUCL30387 | rna-NM_001180138.1_MUCL30387 | cds-NP_010204.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:303775-305572:- | gene-YDL079C_MUCL30388 | rna-NM_001180138.1_MUCL30388 | cds-NP_010204.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:296944-298739:- | gene-YDL079C_MUCL39482 | rna-NM_001180138.1_MUCL39482 | cds-NP_010204.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:218952-220749:- | gene-YDL079C_MUCL42920 | rna-NM_001180138.1_MUCL42920 | cds-NP_010204.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:312874-314671:- | gene-YDL079C_NCIM3186 | rna-NM_001180138.1_NCIM3186 | cds-NP_010204.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:296958-298753:- | gene-YDL079C_NCYC1407 | rna-NM_001180138.1_NCYC1407 | cds-NP_010204.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:303742-305539:- | gene-YDL079C_PE2H3 | rna-NM_001180138.1_PE2H3 | cds-NP_010204.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:303739-305536:- | gene-YDL079C_PE2H4 | rna-NM_001180138.1_PE2H4 | cds-NP_010204.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:312951-314748:- | gene-YDL079C_S288C | rna-NM_001180138.1_S288C | cds-NP_010204.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:120173-121969:+ | gene-YDL079C_SA1 | rna-NM_001180138.1_SA1 | cds-NP_010204.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:314084-315881:- | gene-YDL079C_ThermosaccDry | rna-NM_001180138.1_ThermosaccDry | cds-NP_010204.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:316158-317955:- | gene-YDL079C_VR1 | rna-NM_001180138.1_VR1 | cds-NP_010204.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:311998-313795:- | gene-YDL079C_ZTW1 | rna-NM_001180138.1_ZTW1 | cds-NP_010204.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:314119-315915:- | gene-YDL079C_Sparadoxus | rna-NM_001180138.1_Sparadoxus | cds-NP_010204.1_Sparadoxus | 88.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |