Gene name: MRF1
Reference locus (S288C): YGL143C
Gene biotype: protein_coding
Description: Mitochondrial translation release factor; involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability
Top 10 interactors (score): PTH4 (0.988); MRPL8 (0.891); MRP7 (0.877); MRPS9 (0.874); MRPS16 (0.834); RPS3 (0.77); PUF3 (0.766); YNL122C (0.757); MRPL24 (0.752); IFM1 (0.752); COX2 (0.748); MRPL39 (0.744); MRP17 (0.741); MRPL9 (0.732); MTQ1 (0.73); RRF1 (0.726); IMG1 (0.725); RPL5 (0.725); YLR281C (0.72); RPL25 (0.703)
Homologues (species, bitscore): MTRF1L (Homo sapiens, 230.7); Mtrf1l (Mus musculus, 226.9); mtrf1l (Danio rerio, 247.7); mtrf1l (Xenopus tropicalis, 228.8); CG5705 (Drosophila melanogaster, 216.1); W03F8.3 (Caenorhabditis elegans, 175.3); AT2G47020 (Arabidopsis thaliana, 232.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:237304-238545:- | gene-YGL143C_AKU4011 | rna-NM_001181008.3_AKU4011 | cds-NP_011372.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:166406-167647:+ | gene-YGL143C_BG1 | rna-NM_001181008.3_BG1 | cds-NP_011372.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:239729-240970:- | gene-YGL143C_Bruggeman | rna-NM_001181008.3_Bruggeman | cds-NP_011372.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:235321-236562:- | gene-YGL143C_CAT1 | rna-NM_001181008.3_CAT1 | cds-NP_011372.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:240686-241927:- | gene-YGL143C_CBS1585 | rna-NM_001181008.3_CBS1585 | cds-NP_011372.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:235278-236519:- | gene-YGL143C_CBS436 | rna-NM_001181008.3_CBS436 | cds-NP_011372.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:226896-228137:- | gene-YGL143C_CBS6412 | rna-NM_001181008.3_CBS6412 | cds-NP_011372.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:235242-236483:- | gene-YGL143C_CBS6413 | rna-NM_001181008.3_CBS6413 | cds-NP_011372.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:234979-236220:- | gene-YGL143C_CENPK1137D | rna-NM_001181008.3_CENPK1137D | cds-NP_011372.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:227445-228686:- | gene-YGL143C_EthanolRed | rna-NM_001181008.3_EthanolRed | cds-NP_011372.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:228691-229932:- | gene-YGL143C_FaliES1 | rna-NM_001181008.3_FaliES1 | cds-NP_011372.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:78520-79761:- | gene-YGL143C_JAY291 | rna-NM_001181008.3_JAY291 | cds-NP_011372.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:236699-237940:- | gene-YGL143C_MUCL30387 | rna-NM_001181008.3_MUCL30387 | cds-NP_011372.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:239814-241055:- | gene-YGL143C_MUCL30388 | rna-NM_001181008.3_MUCL30388 | cds-NP_011372.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:237467-238708:- | gene-YGL143C_MUCL39482 | rna-NM_001181008.3_MUCL39482 | cds-NP_011372.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:240688-241929:- | gene-YGL143C_MUCL42920 | rna-NM_001181008.3_MUCL42920 | cds-NP_011372.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:234717-235958:- | gene-YGL143C_NCIM3186 | rna-NM_001181008.3_NCIM3186 | cds-NP_011372.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:228957-230198:- | gene-YGL143C_NCYC1407 | rna-NM_001181008.3_NCYC1407 | cds-NP_011372.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:230823-232064:- | gene-YGL143C_PE2H3 | rna-NM_001181008.3_PE2H3 | cds-NP_011372.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:235818-237059:- | gene-YGL143C_PE2H4 | rna-NM_001181008.3_PE2H4 | cds-NP_011372.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:234717-235958:- | gene-YGL143C_S288C | rna-NM_001181008.3_S288C | cds-NP_011372.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000081.1:18791-20032:+ | gene-YGL143C_SA1 | rna-NM_001181008.3_SA1 | cds-NP_011372.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:228920-230161:- | gene-YGL143C_ThermosaccDry | rna-NM_001181008.3_ThermosaccDry | cds-NP_011372.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:235737-236978:- | gene-YGL143C_VR1 | rna-NM_001181008.3_VR1 | cds-NP_011372.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:227027-228268:- | gene-YGL143C_ZTW1 | rna-NM_001181008.3_ZTW1 | cds-NP_011372.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:233084-234325:- | gene-YGL143C_Sparadoxus | rna-NM_001181008.3_Sparadoxus | cds-NP_011372.3_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |