MRD1 (YPR112C)


Gene profile

Gene name: MRD1
Reference locus (S288C): YPR112C
Gene biotype: protein_coding

Description: Multiple RNA-binding domain-containing protein 1; Essential conserved small ribosomal subunit (40s) synthesis factor; component of the 90S preribosome; required for production of 18S rRNA and small ribosomal subunit; contains five consensus RNA-binding domains and binds to the pre-rRNA at two sites within the 18S region

Top 10 interactors (score): UTP7 (0.999); NOP14 (0.999); NOP9 (0.999); ERB1 (0.999); UTP21 (0.999); NOC4 (0.999); PWP2 (0.999); KRI1 (0.999); TSR1 (0.999); ENP1 (0.999); RRP12 (0.999); NOC2 (0.999); UTP13 (0.999); BMS1 (0.999); BFR2 (0.999); RRP5 (0.999); ENP2 (0.999); DIP2 (0.999); KRE33 (0.999); ROK1 (0.999)

Homologues (species, bitscore): RBM19 (Homo sapiens, 389.8); Rbm19 (Mus musculus, 384.0); rbm19 (Danio rerio, 383.6); rbm19 (Xenopus tropicalis, 388.7); CG3335 (Drosophila melanogaster, 360.5); rbd-1 (Caenorhabditis elegans, 353.6); AT4G19610 (Arabidopsis thaliana, 384.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:721085-723748:- gene-YPR112C_AKU4011 rna-NM_001184209.1_AKU4011 cds-NP_015437.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:174090-176753:+ gene-YPR112C_BG1 rna-NM_001184209.1_BG1 cds-NP_015437.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:800197-802860:- gene-YPR112C_Bruggeman rna-NM_001184209.1_Bruggeman cds-NP_015437.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:843398-846061:- gene-YPR112C_CAT1 rna-NM_001184209.1_CAT1 cds-NP_015437.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:725342-728005:- gene-YPR112C_CBS1585 rna-NM_001184209.1_CBS1585 cds-NP_015437.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:739641-742304:- gene-YPR112C_CBS436 rna-NM_001184209.1_CBS436 cds-NP_015437.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:728065-730728:- gene-YPR112C_CBS6412 rna-NM_001184209.1_CBS6412 cds-NP_015437.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:722789-725452:- gene-YPR112C_CBS6413 rna-NM_001184209.1_CBS6413 cds-NP_015437.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:749241-751904:- gene-YPR112C_CENPK1137D rna-NM_001184209.1_CENPK1137D cds-NP_015437.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1047699-1050362:- gene-YPR112C_EthanolRed rna-NM_001184209.1_EthanolRed cds-NP_015437.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:727246-729909:- gene-YPR112C_FaliES1 rna-NM_001184209.1_FaliES1 cds-NP_015437.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000436.1:18010-20673:- gene-YPR112C_JAY291 rna-NM_001184209.1_JAY291 cds-NP_015437.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:740352-743015:- gene-YPR112C_MUCL30387 rna-NM_001184209.1_MUCL30387 cds-NP_015437.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:739047-741710:- gene-YPR112C_MUCL30388 rna-NM_001184209.1_MUCL30388 cds-NP_015437.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:717849-720512:- gene-YPR112C_MUCL39482 rna-NM_001184209.1_MUCL39482 cds-NP_015437.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:781392-784055:- gene-YPR112C_MUCL42920 rna-NM_001184209.1_MUCL42920 cds-NP_015437.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:749239-751902:- gene-YPR112C_NCIM3186 rna-NM_001184209.1_NCIM3186 cds-NP_015437.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:726443-729106:- gene-YPR112C_NCYC1407 rna-NM_001184209.1_NCYC1407 cds-NP_015437.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:732685-735348:- gene-YPR112C_PE2H3 rna-NM_001184209.1_PE2H3 cds-NP_015437.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:732333-734996:- gene-YPR112C_PE2H4 rna-NM_001184209.1_PE2H4 cds-NP_015437.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:749256-751919:- gene-YPR112C_S288C rna-NM_001184209.1_S288C cds-NP_015437.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000028.1:47370-50033:- gene-YPR112C_SA1 rna-NM_001184209.1_SA1 cds-NP_015437.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:726691-729354:- gene-YPR112C_ThermosaccDry rna-NM_001184209.1_ThermosaccDry cds-NP_015437.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:743352-746015:- gene-YPR112C_VR1 rna-NM_001184209.1_VR1 cds-NP_015437.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:725743-728406:- gene-YPR112C_ZTW1 rna-NM_001184209.1_ZTW1 cds-NP_015437.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:726696-729359:- gene-YPR112C_Sparadoxus rna-NM_001184209.1_Sparadoxus cds-NP_015437.1_Sparadoxus 89.0 99.8 Verified 1 1 1 False True False False False

Additional files