Gene name: MPT5
Reference locus (S288C): YGL178W
Gene biotype: protein_coding
Description: Suppressor protein MPT5; mRNA-binding protein of the PUF family; binds to specific mRNAs, often in the 3' UTR; has broad specificity and binds to more than 1000 mRNAs (16% of the transcriptome); recruits the CCR4-NOT deadenylase complex to mRNAs along with Dhh1p and Dcp1p to promote deadenylation, decapping, and decay; also interacts with the Caf20p translational initiation repressor, affecting its mRNA target specificity
Top 10 interactors (score): POP2 (0.977); CCR4 (0.963); DHH1 (0.953); PUF6 (0.942); CAF20 (0.896); VTS1 (0.88); CAF40 (0.839); PAB1 (0.829); HEK2 (0.82); SSD1 (0.8); PUB1 (0.795); SST2 (0.794); COX17 (0.793); PKC1 (0.789); CDC33 (0.769); CDC39 (0.754); NOT5 (0.727); LRG1 (0.706); DSF2 (0.697); MOT2 (0.695)
Homologues (species, bitscore): PUM2 (Homo sapiens, 161.8); Pum2 (Mus musculus, 161.4); pum1 (Danio rerio, 159.5); pum2 (Xenopus tropicalis, 161.4); pum (Drosophila melanogaster, 171.8); puf-9 (Caenorhabditis elegans, 149.1); PUM2 (Arabidopsis thaliana, 166.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:169921-173139:+ | gene-YGL178W_AKU4011 | rna-NM_001181043.1_AKU4011 | cds-NP_011337.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:237217-240470:- | gene-YGL178W_BG1 | rna-NM_001181043.1_BG1 | cds-NP_011337.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:172120-175338:+ | gene-YGL178W_Bruggeman | rna-NM_001181043.1_Bruggeman | cds-NP_011337.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:167990-171208:+ | gene-YGL178W_CAT1 | rna-NM_001181043.1_CAT1 | cds-NP_011337.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:173060-176278:+ | gene-YGL178W_CBS1585 | rna-NM_001181043.1_CBS1585 | cds-NP_011337.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:167980-171198:+ | gene-YGL178W_CBS436 | rna-NM_001181043.1_CBS436 | cds-NP_011337.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:159523-162741:+ | gene-YGL178W_CBS6412 | rna-NM_001181043.1_CBS6412 | cds-NP_011337.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:167372-170590:+ | gene-YGL178W_CBS6413 | rna-NM_001181043.1_CBS6413 | cds-NP_011337.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:167543-170762:+ | gene-YGL178W_CENPK1137D | rna-NM_001181043.1_CENPK1137D | cds-NP_011337.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:159728-162946:+ | gene-YGL178W_EthanolRed | rna-NM_001181043.1_EthanolRed | cds-NP_011337.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:160974-164192:+ | gene-YGL178W_FaliES1 | rna-NM_001181043.1_FaliES1 | cds-NP_011337.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:11214-14432:+ | gene-YGL178W_JAY291 | rna-NM_001181043.1_JAY291 | cds-NP_011337.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:169367-172585:+ | gene-YGL178W_MUCL30387 | rna-NM_001181043.1_MUCL30387 | cds-NP_011337.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:172454-175672:+ | gene-YGL178W_MUCL30388 | rna-NM_001181043.1_MUCL30388 | cds-NP_011337.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:170084-173302:+ | gene-YGL178W_MUCL39482 | rna-NM_001181043.1_MUCL39482 | cds-NP_011337.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:172675-175893:+ | gene-YGL178W_MUCL42920 | rna-NM_001181043.1_MUCL42920 | cds-NP_011337.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:167352-170571:+ | gene-YGL178W_NCIM3186 | rna-NM_001181043.1_NCIM3186 | cds-NP_011337.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:161549-164766:+ | gene-YGL178W_NCYC1407 | rna-NM_001181043.1_NCYC1407 | cds-NP_011337.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:163514-166732:+ | gene-YGL178W_PE2H3 | rna-NM_001181043.1_PE2H3 | cds-NP_011337.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:163062-166280:+ | gene-YGL178W_PE2H4 | rna-NM_001181043.1_PE2H4 | cds-NP_011337.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:167352-170571:+ | gene-YGL178W_S288C | rna-NM_001181043.1_S288C | cds-NP_011337.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:27118-30390:+ | gene-YGL178W_SA1 | rna-NM_001181043.1_SA1 | cds-NP_011337.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:161203-164421:+ | gene-YGL178W_ThermosaccDry | rna-NM_001181043.1_ThermosaccDry | cds-NP_011337.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:168416-171634:+ | gene-YGL178W_VR1 | rna-NM_001181043.1_VR1 | cds-NP_011337.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:159641-162872:+ | gene-YGL178W_ZTW1 | rna-NM_001181043.1_ZTW1 | cds-NP_011337.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:166497-169730:+ | gene-YGL178W_Sparadoxus | rna-NM_001181043.1_Sparadoxus | cds-NP_011337.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |